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Neuromuscular Blocking Agents in ARDS
New England Journal of Medicine, 2010In this issue of the Journal, Papazian and colleagues1 present intriguing results of their study examining neuromuscular blockade in patients with severe, early acute respiratory distress syndrome (ARDS). The investigators randomly assigned 340 patients to receive the neuromuscular blocking agent cisatracurium or placebo for a period of 48 hours.
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Neuromuscular Blockers and Reversal Agents
DeckerMed Anesthesiology, 2019Neuromuscular blocking drugs, which include depolarizing and nondepolarizing drugs, are used to facilitate intubation and provide skeletal muscle relaxation during surgery and in the intensive care unit. The agents differ in their mechanism, duration of action, side-effect profile, and metabolism.
Jennifer J Yang+3 more
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Neuromuscular blocking and reversal agents
Anaesthesia & Intensive Care Medicine, 2008Abstract The neuromuscular junction consists of the motor nerve terminal, the synaptic cleft and post-synaptic nicotinic receptors on the motor end-plate of striated muscle. Neuromuscular blocking drugs are categorized into depolarizing and non-depolarizing agents.
Khorat Farooq, Jennifer M. Hunter
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