Results 301 to 310 of about 3,364,352 (377)

Mammalian TatD DNase domain containing 1 (TATDN1) is a proteostasis‐responsive gene with roles in ventricular structure and neuromuscular function

open access: yesThe FEBS Journal, EarlyView.
Twin‐arginine translocation D (TatD) homologs are found across all kingdoms, with debated roles in DNA degradation and protein quality control in unicellular organisms. We characterize TATDN1, the mammalian TatD orthologue, as a proteostatic stress‐responsive cytosolic protein dispensable for DNA degradation.
Gisel Barés   +19 more
wiley   +1 more source

Phosphoproteomic analysis reveals the diversity of signaling behind ErbB‐inhibitor‐induced phenotypes

open access: yesThe FEBS Journal, EarlyView.
Whole‐organism phosphoproteomics after ErbB inhibitor treatment was assessed in zebrafish embryos. Differential signaling was uncovered after treatments with more selective ErbB inhibitors and pan‐ErbB inhibitors, despite similar neurological and myocardial phenotypes.
Katri Vaparanta   +10 more
wiley   +1 more source

Neuromuscular monitoring and incidence of postoperative residual neuromuscular blockade: a prospective observational study. [PDF]

open access: yesJ Anesth Analg Crit Care
Piersanti A   +5 more
europepmc   +1 more source

Application of an artificial intelligence–assisted electronic stethoscope for evaluating swallowing function decline across age groups and sex in Japan

open access: yesGeriatrics &Gerontology International, EarlyView.
Pharyngeal clearance time measured by a neck‐worn electronic stethoscope (NWES) became significantly prolonged in older adults, suggesting the potential of the NWES as a noninvasive, quantitative tool for assessing age‐related changes in swallowing function. Aim This preliminary investigation examined whether pharyngeal clearance time (PCT) measured by
Koichiro Matsuo   +6 more
wiley   +1 more source

Real‐World Unmet Needs of Patients With Haemophilia A and Haemophilia B With or Without Inhibitors: End‐of‐Study Results From the explorer6 Non‐Interventional Study

open access: yesHaemophilia, EarlyView.
ABSTRACT Introduction Haemophilia is associated with high disease and treatment burdens. Prospective evaluation of data from patients with haemophilia helps understand and define unmet needs, optimise treatment and improve healthcare outcomes. Aim To present end‐of‐study data from explorer6 (NCT03741881), a prospective, non‐interventional study across ...
Allison P. Wheeler   +14 more
wiley   +1 more source

Risk factors for administration of additional neuromuscular block reversal in adults undergoing general anaesthesia: a single centre retrospective case-control study. [PDF]

open access: yesBMC Anesthesiol
Vishneski SR   +9 more
europepmc   +1 more source

Patient positioning on the operating table and patient safety: A systematic review and meta‐analysis

open access: yesJournal of Advanced Nursing, EarlyView.
Abstract Aim To identify occurrence of harmful incidents related to patient positioning on operating table. Design Systematic review and meta‐analysis. Data Sources Eight databases including Ovid, Medline, Embase, CINAHL, the Cochrane Library, Epistemonikos, Scopus, Web of Science and Google Scholar were systematically searched from the inception of ...
Signe Berit Bentsen   +5 more
wiley   +1 more source

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