Results 301 to 310 of about 95,633 (353)
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International Anesthesiology Clinics, 1988
Clearly, many aspects of the action of neuromuscular blockers remain poorly understood at the molecular level. In the case of competitive blockers, blockade of EPPs by competitive binding to the ACh receptor site accounts for the most clinically important aspect of blockade.
C J, Lingle, J H, Steinbach
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Clearly, many aspects of the action of neuromuscular blockers remain poorly understood at the molecular level. In the case of competitive blockers, blockade of EPPs by competitive binding to the ACh receptor site accounts for the most clinically important aspect of blockade.
C J, Lingle, J H, Steinbach
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Veterinary Clinics of North America: Equine Practice, 2002
In summary, with proper vigilance, neuromuscular blocking agents can be used safely in anesthetized equine patients to optimize conditions for certain surgical procedures. By appropriate use of neuromuscular monitoring techniques and reversal agents, residual blockade and muscle weakness should be avoided, allowing the horse to recover to standing ...
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In summary, with proper vigilance, neuromuscular blocking agents can be used safely in anesthetized equine patients to optimize conditions for certain surgical procedures. By appropriate use of neuromuscular monitoring techniques and reversal agents, residual blockade and muscle weakness should be avoided, allowing the horse to recover to standing ...
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2016
Many drugs used for induction or maintenance of anaesthesia provide a degree of skeletal muscle relaxation, but in general this is only mild to moderate at a surgical plane of anaesthesia. This chapter looks at different ways to achieve more profound muscle relaxation, neuromuscular blocking agents (NMBAs) and their mechanism, monitoring the ...
Renu Agarwal, Priya Mathur
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Many drugs used for induction or maintenance of anaesthesia provide a degree of skeletal muscle relaxation, but in general this is only mild to moderate at a surgical plane of anaesthesia. This chapter looks at different ways to achieve more profound muscle relaxation, neuromuscular blocking agents (NMBAs) and their mechanism, monitoring the ...
Renu Agarwal, Priya Mathur
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Critical Care Medicine, 1993
On logical grounds, the term “neuromuscular-blocking agent” might be applied to any drug, the primary action of which is to interrupt neuromuscular transmission. This chapter discusses those drugs of which the primary site of action is the postjunctional motor endplate cholinoceptors and drugs that are used as muscle relaxants in anaesthetic practice ...
Pam Dulin, Cheryl Williams
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On logical grounds, the term “neuromuscular-blocking agent” might be applied to any drug, the primary action of which is to interrupt neuromuscular transmission. This chapter discusses those drugs of which the primary site of action is the postjunctional motor endplate cholinoceptors and drugs that are used as muscle relaxants in anaesthetic practice ...
Pam Dulin, Cheryl Williams
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Neuromuscular Blocking Agents and Neuromuscular Diseases
2000Acquired neuromuscular diseases or congenital disorders either affect the neuromuscular transmission or the muscle itself. When the neuromuscular transmission is involved, two pathophysiological mechanisms must be distinguished: the abnormality of the nicotinic receptor at the endplate (myasthenia gravis, upregulation of the receptor) and the ...
Benoît Plaud, François Donati
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2010
Neuromuscular blocking agents have, perhaps, the most fascinating history among the drugs used in anesthesiology and intensive care. For centuries, South American aborigines had used curare to hunt animals before Claude Bernard showed in 1850 that these drugs act peripherally, blocking conduction where motor nerves meet the muscle.1 These historical ...
Gerardo Rodríguez +2 more
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Neuromuscular blocking agents have, perhaps, the most fascinating history among the drugs used in anesthesiology and intensive care. For centuries, South American aborigines had used curare to hunt animals before Claude Bernard showed in 1850 that these drugs act peripherally, blocking conduction where motor nerves meet the muscle.1 These historical ...
Gerardo Rodríguez +2 more
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Reactions Weekly, 2012
The effect of different antiepileptic drugs on the pharmacokinetics of various neuromuscular blocking agents including atracurium, cisatracurium, doxacurium, mivacurium, pancuronium, pipecuronium, rapacuronium, rocuronium and vecuronium are described. Also, potential pharmacodynamic interactions are highlighted.
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The effect of different antiepileptic drugs on the pharmacokinetics of various neuromuscular blocking agents including atracurium, cisatracurium, doxacurium, mivacurium, pancuronium, pipecuronium, rapacuronium, rocuronium and vecuronium are described. Also, potential pharmacodynamic interactions are highlighted.
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2017
Neuromuscular blockade is used in the operating room and in the intensive care unit. While in the operating room, almost every patient undergoing general anesthesia receives neuromuscular blocking agents, in the intensive care unit setting, curarization is reserved only to some patients.
Bignami E., Saglietti F.
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Neuromuscular blockade is used in the operating room and in the intensive care unit. While in the operating room, almost every patient undergoing general anesthesia receives neuromuscular blocking agents, in the intensive care unit setting, curarization is reserved only to some patients.
Bignami E., Saglietti F.
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Journal of Pharmacy Practice, 1994
Neuromuscular blocking (NMB) agents are frequently used in the operating room (OR) as well as the intensive care units. The number of NMB agents available for use in these areas continues to increase. The clinician currently has 10 agents from which to choose, with another (rocuronium) soon to be available.
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Neuromuscular blocking (NMB) agents are frequently used in the operating room (OR) as well as the intensive care units. The number of NMB agents available for use in these areas continues to increase. The clinician currently has 10 agents from which to choose, with another (rocuronium) soon to be available.
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Isomeric Carborane Neuromuscular Blocking Agents
ChemMedChem, 2019AbstractWe synthesized a family of neuromuscular blocking agents (NMB) based on decamethonium, but containing a carborane cluster in the methylene chain between the two quaternary ammonium groups. The carborane cluster isomers o‐NMB, m‐NMB, and p‐NMB were tested in animals for neuromuscular block and compared with agents used clinically: rocuronium and
Lalit N. Goswami +8 more
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