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Veterinary Clinics of North America: Equine Practice, 2002
In summary, with proper vigilance, neuromuscular blocking agents can be used safely in anesthetized equine patients to optimize conditions for certain surgical procedures. By appropriate use of neuromuscular monitoring techniques and reversal agents, residual blockade and muscle weakness should be avoided, allowing the horse to recover to standing ...
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In summary, with proper vigilance, neuromuscular blocking agents can be used safely in anesthetized equine patients to optimize conditions for certain surgical procedures. By appropriate use of neuromuscular monitoring techniques and reversal agents, residual blockade and muscle weakness should be avoided, allowing the horse to recover to standing ...
openaire +4 more sources
American Journal of Nursing, 1997
O nene afternoon at her 150bed community hospital, Marcia Czabo, RN, a new nurse manager for the intensive care unit, was conducting a quality improvement survey of stock medications in the medication room. She quickly made two alarming discoveries: She found pancuronium located in the stock box where heparin flush solutions should have been, and ...
Robert Guanci, Linda L. Lilley
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O nene afternoon at her 150bed community hospital, Marcia Czabo, RN, a new nurse manager for the intensive care unit, was conducting a quality improvement survey of stock medications in the medication room. She quickly made two alarming discoveries: She found pancuronium located in the stock box where heparin flush solutions should have been, and ...
Robert Guanci, Linda L. Lilley
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Journal of Medicinal Chemistry, 2022
Broad-spectrum agents for the reversal of residual curarization induced by neuromuscular blocking agents are of great significance. Here, we report a highly water-soluble cucurbit[8]uril (CB[8]) derivative as a broad-spectrum neuromuscular block reversal
Hong-Kun Liu +13 more
semanticscholar +1 more source
Broad-spectrum agents for the reversal of residual curarization induced by neuromuscular blocking agents are of great significance. Here, we report a highly water-soluble cucurbit[8]uril (CB[8]) derivative as a broad-spectrum neuromuscular block reversal
Hong-Kun Liu +13 more
semanticscholar +1 more source
2010
Neuromuscular blocking agents have, perhaps, the most fascinating history among the drugs used in anesthesiology and intensive care. For centuries, South American aborigines had used curare to hunt animals before Claude Bernard showed in 1850 that these drugs act peripherally, blocking conduction where motor nerves meet the muscle.1 These historical ...
Rafael Ortega +2 more
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Neuromuscular blocking agents have, perhaps, the most fascinating history among the drugs used in anesthesiology and intensive care. For centuries, South American aborigines had used curare to hunt animals before Claude Bernard showed in 1850 that these drugs act peripherally, blocking conduction where motor nerves meet the muscle.1 These historical ...
Rafael Ortega +2 more
openaire +2 more sources
Critical Care Medicine, 1993
On logical grounds, the term “neuromuscular-blocking agent” might be applied to any drug, the primary action of which is to interrupt neuromuscular transmission. This chapter discusses those drugs of which the primary site of action is the postjunctional motor endplate cholinoceptors and drugs that are used as muscle relaxants in anaesthetic practice ...
Cheryl J. Williams, Pam Dulin
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On logical grounds, the term “neuromuscular-blocking agent” might be applied to any drug, the primary action of which is to interrupt neuromuscular transmission. This chapter discusses those drugs of which the primary site of action is the postjunctional motor endplate cholinoceptors and drugs that are used as muscle relaxants in anaesthetic practice ...
Cheryl J. Williams, Pam Dulin
openaire +2 more sources
2016
Many drugs used for induction or maintenance of anaesthesia provide a degree of skeletal muscle relaxation, but in general this is only mild to moderate at a surgical plane of anaesthesia. This chapter looks at different ways to achieve more profound muscle relaxation, neuromuscular blocking agents (NMBAs) and their mechanism, monitoring the ...
Derek Flaherty, Adam Auckburally
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Many drugs used for induction or maintenance of anaesthesia provide a degree of skeletal muscle relaxation, but in general this is only mild to moderate at a surgical plane of anaesthesia. This chapter looks at different ways to achieve more profound muscle relaxation, neuromuscular blocking agents (NMBAs) and their mechanism, monitoring the ...
Derek Flaherty, Adam Auckburally
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2017
Neuromuscular blockade is used in the operating room and in the intensive care unit. While in the operating room, almost every patient undergoing general anesthesia receives neuromuscular blocking agents, in the intensive care unit setting, curarization is reserved only to some patients.
Bignami E., Saglietti F.
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Neuromuscular blockade is used in the operating room and in the intensive care unit. While in the operating room, almost every patient undergoing general anesthesia receives neuromuscular blocking agents, in the intensive care unit setting, curarization is reserved only to some patients.
Bignami E., Saglietti F.
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Neuromuscular Blocking Agents and Neuromuscular Diseases
2000Acquired neuromuscular diseases or congenital disorders either affect the neuromuscular transmission or the muscle itself. When the neuromuscular transmission is involved, two pathophysiological mechanisms must be distinguished: the abnormality of the nicotinic receptor at the endplate (myasthenia gravis, upregulation of the receptor) and the ...
Benoit Plaud, François Donati
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Neuromuscular blocking agents and reversal agents
Anaesthesia & Intensive Care Medicine, 2005Abstract The neuromuscular blocking agents in routine clinical use may be classed as depolarizing or nondepolarizing. Suxamethonium is the only example of the depolarizing group and is an agonist at the neuromuscular receptor. It has the most rapid onset and the shortest duration of action, though it has a number of important unwanted side-effects ...
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Fatal anaphylaxis with neuromuscular blocking agents: a risk factor and management analysis.
Allergy. European Journal of Allergy and Clinical Immunology, 2014BACKGROUND Anaphylactic reactions to neuromuscular blocking agents (NMBAs) can be severe and even fatal. Our aim was to evaluate mortality rate in France from anaphylactic reactions to NMBAs, to identify risk factors for a fatal outcome, and to describe ...
M. Reitter +7 more
semanticscholar +1 more source