Vascular Calcification: Mechanisms, Models, and Therapies
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu +5 more
wiley +1 more source
The effect of dexmedetomidine on rocuronium-induced neuromuscular blockade and its reversal by sugammadex. [PDF]
Fedor M +3 more
europepmc +1 more source
Immunomodulation of the Prostate Tumor Microenvironment Following Inorganic Arsenic Exposure
ABSTRACT The tumor microenvironment (TME) influences prostate cancer (PCa) progression through stromal and immune interactions. Adipose‐derived mesenchymal stromal cells (ASCs) modulate immune tone, while inorganic arsenic (iAs), a widespread toxicant, is linked to immune suppression and carcinogenesis.
Joseph J. Shearer +4 more
wiley +1 more source
Succinylcholine and neuromuscular blockade monitoring [PDF]
A, Sabate, M, Koo, D, Lopez
openaire +2 more sources
Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley +1 more source
Guideline-Concordant Sedative and Analgesia Use in Critically Ill Patients Receiving Sustained Neuromuscular Blockade. [PDF]
Feeney ME +4 more
europepmc +1 more source
Abstract Background Hospitalized patients often experience poor sleep, which is associated with worse health outcomes, increased rates of delirium, and readmissions. Objective To improve overnight sleep for clinically stable general neurology patients at a single academic center.
Noor F. Shaik +19 more
wiley +1 more source
From optimization of surgical conditions to modulation of systemic inflammation: revisiting the implications of deep neuromuscular blockade. [PDF]
Lee S.
europepmc +1 more source
ABSTRACT Lung injury is a common complication in critical sepsis. PRMT5 is implicated in endothelial inflammation and lung diseases, but its role in sepsis‐associated lung injury remains unclear. This study collected clinical sepsis samples and detected the mRNA expression of PRMT5.
Bo Wang, Zhen Ge, Fei‐Xiang Chen
wiley +1 more source
Breaking the block: Sugammadex as the last resort for refractory vecuronium-induced neuromuscular blockade in a patient receiving hydroxychloroquine. [PDF]
Verma S, Sarkar S.
europepmc +1 more source

