Results 51 to 60 of about 17,596 (164)

Intubating conditions during rapid sequence induction with either rocuronium or suxamethonium in elderly patients. A randomised study

Acta Anaesthesiologica Scandinavica, Volume 69, Issue 3, March 2025.
Abstract Background During rapid sequence induction, either rocuronium 1.0 mg kg−1 or suxamethonium 1.0 mg kg−1 can be administered to facilitate endotracheal intubation. We hypothezised that rocuronium provided a larger proportion of excellent intubating conditions compared to suxamethonium in elderly patients.
Matias Vested, Andreas Creutzburg, Christian S. Meyhoff, Marie Louise Rovsing, Tatiana Nielsen, Fabio Rosa, Eske K Aasvang, Hannah Mollerup, Thomas Fuchs‐Buder, Lars Simon Rasmussen   +9 more
wiley   +1 more source

Lack of a Hyperkalemic Response in Emergency Department Patients Receiving Succinylcholine [PDF]

, 1995
Objective: To determine whether serum potassium (K) levels increase significantly following succinylcholine (SCh)-assisted intubation in ED patients. Methods: A prospective. noncontrolled, consecutive case series design was used to evaluate the change in
Antognini, Bourke, Brooke, Delphin, Dronen, Groncrt, Henderson, Iwatsuki, Khan, Kopriva, Linter, Mane, Morris, O'Connor, Roberts, Schaner, Schneider, Schwartz, Smith, Stevenson, Sullivan, Thomas, Tolmie, Tong, Yentis   +24 more
core   +1 more source

Pediatric Anesthetic Management of a Patient With an ALG‐13 Gene Mutation, a Rare Congenital Disorder of Glycosylation

Clinical Case Reports, Volume 13, Issue 1, January 2025.
ABSTRACT Congenital disorders of glycosylation are rare and present a challenge in management due to interactions with intraoperative medications. We present safe and successful anesthetic management of a pediatric patient with an ALG‐13 gene mutation.
Esha Thakkar, John A. Iasiello, Sunny R. Cai, Adrienne Hutton   +3 more
wiley   +1 more source

Influence Of Stimulus Frequency On Blockade Induced By Pancuronium And Rocuronium: Study On Rats Phrenic Nerve-diaphragm Preparation. [PDF]

, 2015
To evaluate the influence of two stimulation frequencies on the installation of neuromuscular blockade produced by pancuronium and rocuronium on the rat diaphragm.
Araujo, Daniele Ribeiro de, Braga, Angélica de Fátima de Assunção, Braga, Franklin Sarmento da Silva, Mantovani, Mario, Munoz, Derli Conceição, Potério, Glória Maria Braga   +5 more
core  

Hypofibrinogenemia Following an Anaphylactic Shock Caused by a Neuromuscular Blocking Agent—Case Report

Case Reports in Critical Care, Volume 2025, Issue 1, 2025.
Anaphylaxis, the most severe form of allergic reaction, has a prevalence of 1/5000–1/20,000 following general anesthesia. Numerous substances used in anesthesia, such as induction agents and muscle relaxants, can potentially trigger anaphylactic reactions.
Michael Iarossi, Caroline van de Wyngaert, Véronique Hamoir, Geoffroy Vanderweerden, Cedric Hermans, Chiara Lazzeri   +5 more
wiley   +1 more source

Caffeine Acts as an Agonist of Siglec‐6, Inhibits MRGPRX2‐Triggered Mast Cell Degranulation and Anaphylactoid Reactions

Mediators of Inflammation, Volume 2025, Issue 1, 2025.
Background: Mast cells (MCs) are effectors of anaphylactoid reactions. Mas‐related G‐protein‐coupled receptor X2 (MRGPRX2) receptor mediates the direct activation of MCs in anaphylactoid disease. Siglec‐6 negatively regulates MC activation and is a promising target in the development of antianaphylactoid reaction drugs.
Yuanyuan Ding, Na Wang, Chenrui Zhao, Hongfen Du, Yujuan Yuan, Tao Zhang, Hongli An, Yasumasa Kato   +7 more
wiley   +1 more source

Impact of anesthesia drugs on digestive motility measurements in humans: A systematic review

Neurogastroenterology &Motility, Volume 36, Issue 9, September 2024.
Abstract Background and Purpose Measurement of gastro‐intestinal motility is increasingly performed under general anesthesia during endoscopic or surgical procedures. The aim of the present study was to review the impact of different anesthetic agents on digestive motility measurements in humans.
Domitille Renard, Thomas Clavier, Guillaume Gourcerol, Charlotte Desprez   +3 more
wiley   +1 more source

Rocuronium has a suppressive effect on platelet function via the p2y12 receptor pathway in vitro that is not reversed by sugammadex [PDF]

, 2020
Rocuronium is an aminosteroid nondepolarizing neuromuscular blocker that is widely used for anesthesia and intensive care. In this study, we investigated the effect of rocuronium on human platelet functions in vitro. The effects of rocuronium on platelet
Fukuda, Kazuhiko, Kawamoto, Shuji, Murata, Yutaka   +2 more
core   +1 more source

Association between reversal agents (sugammadex vs. neostigmine) for neuromuscular block and postoperative pulmonary complications: A retrospective analysis

British Journal of Clinical Pharmacology, Volume 90, Issue 7, Page 1667-1676, July 2024.
Aims Residual neuromuscular blockade has been linked to pulmonary complications in the postoperative period. This study aimed to determine whether sugammadex was associated with a lower risk of postoperative pulmonary complications (PPCs) compared with neostigmine.
Aolin Ren, Meihan Fan, Zhen Gu, Xiao Liang, Liuhang Xu, Chengjun Liu, Dutian Wang, Hanxuan Chang, Minmin Zhu   +8 more
wiley   +1 more source

Peripheral nervous system and neuromuscular disorders in the emergency department: A review

Academic Emergency Medicine, Volume 31, Issue 4, Page 386-397, April 2024.
Abstract Introduction Acute presentations and emergencies in neuromuscular disorders (NMDs) often challenge clinical acumen. The objective of this review is to refine the reader's approach to history taking, clinical localization and early diagnosis, as well as emergency management of neuromuscular emergencies.
Ajith Sivadasan, Miguel A. Cortel‐LeBlanc, Achelle Cortel‐LeBlanc, Hans Katzberg   +3 more
wiley   +1 more source