Results 131 to 140 of about 245,637 (381)

Rigidity and flexibility in protein-protein interaction networks: a case study on neuromuscular disorders [PDF]

arXiv, 2014
Mutations in proteins can have deleterious effects on a protein's stability and function, which ultimately causes particular diseases. Genetically inherited muscular dystrophies (MDs) include several genetic diseases, which cause increasing weakness in muscles and disability to perform muscular functions progressively.
arxiv  

Mechanical Stress Induced NOX2 Promotes Endothelial Dysfunction in Ventilator‐Induced Lung Injury: Potential Treatment with Quercetin

Advanced Science, EarlyView.
Abnormal mechanical stretch induced by mechanical ventilation (MV) disrupts endothelial junctions via the NOX2/ROS/CaMKII/ERK1/2 axis both in human aortic endothelial cells (HAECs) in vitro and in ventilator‐induced lung injury (VILI) in mice. Quercetin, an antioxidant predicted to bind to NOX2, can effectively prevent mechanical stretch‐induced ...
Tao Jiang, Yabing Zhang, Zhiye Guo, He Ren, Weiyi Hu, Qingping Yao, Yunlong Huo, Yingxin Qi, Kai Huang   +8 more
wiley   +1 more source

Hippocampal subfield and anterior-posterior segment volumes in patients with sporadic amyotrophic lateral sclerosis

NeuroImage: Clinical, 2021
Neuroimaging studies of hippocampal volumes in patients with amyotrophic lateral sclerosis (ALS) have reported inconsistent results. Our aims were to demonstrate that such discrepancies are largely due to atrophy of different regions of the hippocampus ...
Shuangwu Liu, Qingguo Ren, Gaolang Gong, Yuan Sun, Bing Zhao, Xiaotian Ma, Na Zhang, Suyu Zhong, Yan Lin, Wenqing Wang, Rui Zheng, Xiaolin Yu, Yan Yun, Dong Zhang, Kai Shao, Pengfei Lin, Ying Yuan, Tingjun Dai, Yongqing Zhang, Ling Li, Wei Li, Yuying Zhao, Peiyan Shan, Xiangshui Meng, Chuanzhu Yan   +24 more
doaj  

Treatment of Neuromuscular Diseases Advences in Neurology Volume 17 [PDF]

, 1978
J. A. Simpson
openalex   +1 more source

Motor Unit Number Estimation via Sequential Monte Carlo [PDF]

arXiv, 2018
A change in the number of motor units that operate a particular muscle is an important indicator for the progress of a neuromuscular disease and the efficacy of a therapy. Inference for realistic statistical models of the typical data produced when testing muscle function is difficult, and estimating the number of motor units from these data is an ...
arxiv  

Wireless Technologies for Wearable Electronics: A Review

Advanced Electronic Materials, EarlyView.
This review discusses recent advancements in wireless wearable electronics, focusing on communication technologies and power solutions. It covers key design considerations, explores wireless protocols from short‐ to long‐range networks, and examines powering methods such as integrated sources and energy harvesting.
Choong Yeon Kim, Juhyun Lee, Eun Young Jeong, Yeji Jang, Heesoo Kim, Bohyung Choi, Donggi Han, Youngjun Oh, Jae‐Woong Jeong   +8 more
wiley   +1 more source

Molecular genetics of neurological and neuromuscular disease [PDF]

, 1988
S Bundey
openalex   +1 more source

Splicing therapy for neuromuscular disease

Molecular and Cellular Neuroscience, 2013
Duchenne muscular dystrophy (DMD) and spinal muscular atrophy (SMA) are two of the most common inherited neuromuscular diseases in humans. Both conditions are fatal and no clinically available treatments are able to significantly alter disease course in either case.
Douglas, Andrew G.L., Wood, Matthew J.A.
openaire   +6 more sources

Risk Factors and Predictive Models for Sarcopenia in Older Adults

AGING MEDICINE, EarlyView.
Independent risk factors for sarcopenia identified by Lasso regression and logistic regression in the study were BMI, prealbumin, albumin/globulin ratio (A/G ratio), serum creatinine, and phosphorus. These factors were used to construct a nomogram model and a decision tree model. Both models showed effectiveness in predicting sarcopenia in older adults,
Shiyuan Zhang, Xue Yang, Nina An, Meng Lv, Lanyu Yang, Rui Liu, Song Hu, Weiguo Chen, Wenjing Feng, Yongjun Mao   +9 more
wiley   +1 more source

Lysosomal dysfunction and overload of nucleosides in thymidine phosphorylase deficiency of MNGIE

Journal of Translational Medicine
Inherited deficiency of thymidine phosphorylase (TP), encoded by TYMP, leads to a rare disease with multiple mitochondrial DNA (mtDNA) abnormalities, mitochondrial neurogastrointestinal encephalomyopathy (MNGIE).
Jixiang Du, Fuchen Liu, Xihan Liu, Dandan Zhao, Dongdong Wang, Hongsheng Sun, Chuanzhu Yan, Yuying Zhao   +7 more
doaj   +1 more source