Results 131 to 140 of about 9,500,261 (386)

Improving translational studies: lessons from rare neuromuscular diseases [PDF]

, 2015
Animal models play a key role in the development of novel treatments for human disease. This is particularly true for rare diseases – defined as disorders that affect less than 1 in 2000 people in the human population – for which, very often, there are ...
Wells, D J
core   +3 more sources

Soft and Strong: Elastic Conductors with Bio‐Inspired Self‐Protection

Advanced Materials, EarlyView.
A general reverse‐engineering approach is demonstrated for designing functional yarns that uses woven fabric architecture as a structural framework. The fabric‐based stretchable conductive yarns combine flexibility, high elasticity, low stiffness, self‐protection, and weavability with conventional textile processes. By fine‐tuning the number of elastic
Chenglong Zhang, Xiulun Yin, Chris Zhou, Xin Lu, Siying Wu, Ying Li, Addie Bahi, Sukhneet Kaur Dhillon, Orlando J. Rojas, Jinhua Jiang, Nanliang Chen, Frank K. Ko, John D. W. Madden   +12 more
wiley   +1 more source

From Doubt to Diagnosis: Canadian Patient Perspectives on a Limb‐Girdle Muscular Dystrophy Diagnosis

Health Expectations
Introduction Limb‐girdle muscular dystrophies (LGMDs) encompass a rare and genetically diverse set of disorders, posing challenges in diagnosis due to the absence of distinct pathological features, leading to frequent misdiagnoses and inadequate symptom ...
Homira Osman, Zainab Adamji, Gerald Pfeffer, Jodi Warman‐Chardon, Pryamvada Varma, Jenna Keindel, Stacey Lintern   +6 more
doaj   +1 more source

Optic atrophy 1 mediates muscle differentiation by promoting a metabolic switch via the supercomplex assembly factor SCAF1

iScience
Summary: Myogenic differentiation is integral for the regeneration of skeletal muscle following tissue damage. Though high-energy post-mitotic muscle relies predominantly on mitochondrial respiration, the importance of mitochondrial remodeling in ...
Matthew Triolo, Nicole Baker, Soniya Agarwal, Nikita Larionov, Tina Podinić, Mireille Khacho   +5 more
doaj   +1 more source

Next generation sequencing in a large cohort of patients presenting with neuromuscular disease before or at birth

Orphanet Journal of Rare Diseases, 2015
BackgroundFetal akinesia/hypokinesia, arthrogryposis and severe congenital myopathies are heterogeneous conditions usually presenting before or at birth.
E. Todd, K. Yau, R. Ong, J. Slee, G. McGillivray, C. Barnett, G. Haliloglu, B. Talim, Z. Akcoren, A. Kariminejad, A. Cairns, N. Clarke, M. Freckmann, N. Romero, Denise Williams, C. Sewry, A. Colley, M. Ryan, C. Kiraly-Borri, P. Sivadorai, R. Allcock, D. Beeson, S. Maxwell, M. Davis, N. Laing, G. Ravenscroft   +25 more
semanticscholar   +1 more source

Review of Multifunctional Neural Probe

Advanced Materials Interfaces, EarlyView.
Modern multifunctional neural probes for brain‐machine interfaces extend beyond basic electrical functions to incorporate chemical and optical modalities. This review explores recent advances in multifunctional probes developed for neural signal acquisition and stimulation, highlighting how these innovations enhance the precision of brain activity ...
Ziqi Jia, Yong Kyu Yoon
wiley   +1 more source

Critical Illness Neuromuscular Disease

Pediatric Neurology Briefs, 1995
Four children with critical illness neuromuscular disease following prolonged dependency on a ventilator are reported from the Departments of Neurology and Pediatrics, West Virginia University Health Sciences Center, Morgantown, and the Department of ...
J Gordon Millichap
doaj   +1 more source

Treatment of Neuromuscular Diseases Advences in Neurology Volume 17 [PDF]

, 1978
J. A. Simpson
openalex   +1 more source

Advanced Materials in Responsible Electronics: Innovations for Sustainability, Health, and Circularity

Advanced Materials Technologies, EarlyView.
Contemporary electronic devices produce significant waste, harming ecosystems. Innovation in design, consumption, materials, and end‐of‐life management is crucial. This review explores advanced materials for sustainable and responsible electronics, highlighting their potential to reduce environmental and health hazards while improving device ...
Rawan Omar, Jiawei Yang, Tan‐Phat Huynh, Kiran Gulia, Sooyun Caroline Tavolacci, Weiwei Wu, Yan Wang, Hossam Haick   +7 more
wiley   +1 more source

Splicing therapy for neuromuscular disease

Molecular and Cellular Neuroscience, 2013
Duchenne muscular dystrophy (DMD) and spinal muscular atrophy (SMA) are two of the most common inherited neuromuscular diseases in humans. Both conditions are fatal and no clinically available treatments are able to significantly alter disease course in either case.
Douglas, Andrew G.L., Wood, Matthew J.A.
openaire   +6 more sources