Results 311 to 320 of about 245,637 (381)

Function of the Normal Neuromuscular Junction in Young Children

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims The repetitive nerve stimulation (RNS) test is fundamental to test the functional integrity of the neuromuscular junction. RNS data are scarce for newborns and young children, limiting early diagnostic efforts to identify children with neuromuscular diseases. Here, we performed RNS in young children.
Márk Kozák, Katalin Szatmári, Erzsébet Németh, Béla Fülesdi, Attila Nagy, Attila Tóth, Judit Boczán   +6 more
wiley   +1 more source

Modeling neuromuscular diseases

Mathematical Modelling, 1986
openaire   +2 more sources

Multi‐Frequency Electrical Impedance Myography as a Predictor of Muscle Function in Older Adults

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims This study examined the potential of multi‐frequency electrical impedance myography (EIM) to predict hand grip strength (HGS) variability among adults, including a large proportion of older adults, with and without sarcopenia.
Niladri Kumar Mahato, Buket Sonbas Cobb, Seward B. Rutkove, W. David Arnold, Brian C. Clark   +4 more
wiley   +1 more source

MGBase: A Global, Observational Registry for Collaborative Research in Myasthenia Gravis

Muscle &Nerve, EarlyView.
ABSTRACT Introduction/Aims Patient registries are valuable tools for outcomes research in rare diseases such as myasthenia gravis (MG). Existing MG registries are limited by factors including a lack of geographical scope. MGBase has been designed as a global, observational registry aimed at studying clinical practice outcomes in MG.
Katherine A. Buzzard, Anneke Van der Walt, Helmut Butzkueven, Wen Wen Zhang, Carolina Barnett‐Tapia, Gary Cutter, Jeannine M. Heckmann, Pamela Farr, Carolyn Tran, Charlotte Sartori, Dusko Stupar, Rein More, Linda Sim, Alison Le, Qingxiao Tang, Stephen W. Reddel, the MGBase Study Group, Stefan Blum, Gabvor Lovas, Pamela McCombe, Elisabeth Chroni, Belinda Cruse, Raed Alroughani, John Tzartos, Enrique Gomex‐Figueroa, Cavit Boz, Guntis Karelis, Allan Kermode, Nicholas Crump   +28 more
wiley   +1 more source

Targeting gut microbiota as a therapeutic approach for neurodegenerative diseases

Neuroprotection, EarlyView.
The abstract depicts the gut‐brain axis, illustrating the bidirectional communication between the gastrointestinal tract and the central nervous system. Probiotics can induce the production of neurotrophins, neurotransmitters, SCFAs, and contribute to increased antioxidant levels, which can benefit brain health. In contrast, antibiotics can disrupt the
Tobiloba S. Olajide, Omamuyovwi M. Ijomone   +1 more
wiley   +1 more source

Patterns of Direct Oral Anticoagulant Use in Pediatric Patients: Results From a Multicenter National Database

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Direct oral anticoagulants (DOACs) have quickly gained favor due to oral availability, favorable risk profile, and reduced lab monitoring. This study aims to evaluate trends in DOAC use among pediatric patients with new venous thrombotic events (VTE) and factors associated with their selection.
Molly Mack, Frederico Xavier, Meghan McCormick   +2 more
wiley   +1 more source

Whole Genome Sequencing in Prenatal Diagnostics: The Danish Approach to Guideline Formation and Implementation Within Public Healthcare

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective To describe the implementation of whole genome sequencing (WGS) in prenatal diagnostics and outline the national guideline system facilitating this. Methods Clinical guidelines for WGS in prenatal diagnostics were developed and implemented by the Danish Fetal Medicine Society.
Ida Vogel, Lotte Andreasen, Marie Balslev‐Harder, Naja Becher, Anja Ernst, Kasper Gadsbøll, Tina Duelund Hjortshøj, Marie Skov Hvidbjerg, Martin Larsen, Stina Lou, Ida Charlotte Bay Lund, Lars Henning Pedersen, Laura Kirstine Sønderberg Roos, Lene Sperling, Lone Sunde, Pernille Mathiesen Tørring, Cathrine Vedel, Olav Bjørn Petersen   +17 more
wiley   +1 more source

Guideline for the diagnosis, treatment, and prevention of respiratory syncytial virus infection in children in China

Pediatric Investigation, EarlyView.
ABSTRACT Respiratory syncytial virus (RSV) is one of the most common respiratory pathogens in children under 5 years of age worldwide and it seriously threatens children's health. In recent years, great progress has been made in the field of RSV‐related diseases.
Committee of Pediatrics, China Medical Education Association, Subspecialty Group of Respiratory Diseases, Society of Pediatrics, Chinese Medical Association, Pediatric Respiratory Work Committee, Society of Pulmonologists, Chinese Medical Doctor Association, Committee of Pediatrics, Chinese Research Hospital Association, Pediatric Professional Committee of China Non‐public Medical Institution Association, Professional Committee of Children's Health and Pharmaceutical Research, China Association of Traditional Chinese Medicine, Children's Safe Medication Branch of China Medical News and Information Association, Pediatric Expert Committee of China Primary Health Care Foundation, Global Pediatric Respiratory Alliance, Beijing Hairun Charity Foundation   +16 more
wiley   +1 more source

Effect of creatine monohydrate on motor function in children with facioscapulohumeral muscular dystrophy: A multicenter, randomized, double‐blind placebo‐controlled crossover trial

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, EarlyView.
Abstract Background Facioscapulohumeral muscular dystrophy (FSHD) is a rare, progressive muscle disease with no available disease‐modifying therapy. Creatine monohydrate (CrM) has been shown to improve muscle strength in individuals with muscular dystrophies but has not been tested in young people with FSHD.
Ian R. Woodcock, Katy de Valle, Anita Cairns, Zoe E. Davidson, Michael Kean, Nisha Varma, Anneke Grobler, David Metz, Kate Carroll, Nuran Dilek, Chad Heatwole, Monique M. Ryan, Martin B. Delatycki, Eppie M. Yiu   +13 more
wiley   +1 more source