Results 21 to 30 of about 2,312,065 (203)
Scientific Reports, 2021 Horse racing is a popular and financially important industry worldwide and researchers and horse owners are interested in genetic and training influences that maximise athletic performance.
Victoria O’Hara +5 more
doaj +1 more source
Biomedicines, 2022 The complement system plays a key role in myasthenia gravis (MG). Anti-complement drugs are emerging as effective therapies to treat anti-acetylcholine receptor (AChR) antibody-positive MG patients, though their usage is still limited by the high costs ...
Nicola Iacomino +11 more
doaj +1 more source
BDNF-dependent modulation of axonal transport is selectively impaired in ALS
Acta Neuropathologica Communications, 2022 Axonal transport ensures long-range delivery of essential cargoes between proximal and distal compartments, and is needed for neuronal development, function, and survival.
Andrew P. Tosolini +5 more
doaj +1 more source
Genetic neuromuscular disease [PDF]
Journal of Neurology, Neurosurgery & Psychiatry, 2002 The clinical practice of neuromuscular disease is currently undergoing enormous change as a direct result of the wealth of recent molecular genetic discoveries. Indeed, the majority of gene discoveries in the area of neurological disease relate to neuromuscular disorders.
Mary M, Reilly, Michael G, Hanna
openaire +2 more sources
Neurology and Therapy, 2023 Background We have aimed to assess whether muscle thickness ultrasound (US) shows differences between patients with chronic inflammatory demyelinating polyneuropathy (CIDP), chronic axonal polyneuropathy (CAP), and other neuromuscular (NM) diseases ...
Sara A. Alnajjar +5 more
doaj +1 more source
Myotonic Dystrophy Type 2 and Autoimmune Diseases
, 2023 s of the 17th International Congress on Neuromuscular Diseases (ICNMD 2022): S209 (eP02.06.02672 ...
Ivanović, V. +9 more
core +1 more source
BMC Neurology, 2020 Background Myasthenia gravis is an autoimmune disease mediated by antibodies against proteins associated with the postsynaptic membrane of the neuromuscular junction. Several drugs may trigger an exacerbation of the disease.
Velina Nedkova-Hristova +2 more
doaj +1 more source
The Neuromuscular Junction: Roles in Aging and Neuromuscular Disease [PDF]
International Journal of Molecular Sciences, 2021 The neuromuscular junction (NMJ) is a specialized synapse that bridges the motor neuron and the skeletal muscle fiber and is crucial for conversion of electrical impulses originating in the motor neuron to action potentials in the muscle fiber. The consideration of contributing factors to skeletal muscle injury, muscular dystrophy and sarcopenia cannot
Shama R. Iyer +2 more
openaire +2 more sources
Hyperkalemic Periodic Paralysis: Case Report with a SCNA4 Gene Mutation and Literature Review
Case Reports in Genetics, 2020 Hyperkalemic periodic paralysis is a rare musculoskeletal disorder characterized by episodic muscle weakness associated with hyperkalemia. It is a channelopathy associated with point mutations in the SCNA4 gene, with an autosomal dominant pattern of ...
Manuela Quiroga-Carrillo +3 more
doaj +1 more source
Long-term treatment with subcutaneous immunoglobulin in multifocal motor neuropathy
Scientific Reports, 2021 Multifocal motor neuropathy (MMN) is a rare disease with a prevalence of less than 1 per 100,000 people. Intravenous immunoglobulin (IVIG) therapy, performed for a long-term period, has been demonstrated able to improve the clinical picture of MMN ...
Luca Gentile +6 more
doaj +1 more source