Clinical Pharmacology &Therapeutics, EarlyView.The Joint Heads of Medicines Agencies and European Medicines Agency's (HMA/EMA) big data initiative paves the way for better integration of real‐world data, including data from patient registries, into regulatory decisions on medicines. This article focuses on the outcome of a two‐day multistakeholder workshop organized by EMA in 2024, which explored ...
Kelly Plueschke +24 more
wiley +1 more source
Neuromuscular monitoring: useless, optional or mandatory? [PDF]
, 1998 François Donati
openalex +1 more source
A comparative study of different induction techniques (Propofol-Placebo, Propofol-Ephedrine and Propofol- Placebo-Crystalloid) on intubating conditions after rocuronium administration [PDF]
, 2007 This was a prospective randomized double blind controlled study to compare intubating conditions at 60 seconds with rocuronium 0.6 mg/kg by using three different induction techniques: propofol-placebo (PP), propofol-ephedrine (PE) and propofol ...
Karis Misiran,, Muhd Helmi Azmi,
core
Drug Testing and Analysis, EarlyView.The metabolism and urinary elimination of two substances recently classified as prohibited substances in sport was conducted, yielding suitable target analytes for efficient doping controls employing routinely applied chromatographic‐mass spectrometric test methods.
Luisa Euler +4 more
wiley +1 more source
Use of sugammadex in patients with neuromuscular disorders: a systematic review of case reports
BMC Anesthesiology, 2019 Background Sugammadex is a modified gamma-cyclodextrin that acts by selectively encapsulating free amino-steroidal neuromuscular relaxants. Several case reports have been published on the use of sugammadex in patients with neuromuscular disorders that ...
Usha Gurunathan +2 more
doaj +1 more source
A Shape-Based Functional Index for Objective Assessment of Pediatric Motor Function [PDF]
arXivClinical assessments for neuromuscular disorders, such as Spinal Muscular Atrophy (SMA) and Duchenne Muscular Dystrophy (DMD), continue to rely on subjective measures to monitor treatment response and disease progression. We introduce a novel method using wearable sensors to objectively assess motor function during daily activities in 19 patients with ...
arxiv
Influence of surgery and rehabilitation conditioning on psychophysiological fitness [PDF]
, 2008 The purpose of this study was to assess changes in psychophysiological fitness following reconstructive knee surgery and early phase (2.5 months) physical rehabilitation. Nine patients (7 male, 2 female; mean age, 29.9 years) electing to undergo anterior
Bailey, A +4 more
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Immune Checkpoint Inhibitors and Cardiovascular Adverse Events
ESC Heart Failure, EarlyView.Abstract In the last years, we assisted to a tremendous increase in therapeutic options for the management of cancers, with immunotherapy at the forefront of this innovation. Immune checkpoint inhibitors (ICIs) have been developed to enhance the activity of the immune system against cancer cells (1) and the number of approvals for ICIs has rapidly ...
Maria Luisa De Perna +4 more
wiley +1 more source
Effect of MTU length on child-adult difference in neuromuscular fatigue [PDF]
Medicine & Science in Sports & exercise, ACSM, In press, 2019 Purpose The purpose of this study was to compare the development and etiology of neuromuscular fatigue of the knee extensor muscles (KE) at different muscle-tendon unit (MTU) lengths during repeated maximal voluntary isometric contractions (MVIC) between boys and men.Methods Twenty-two pre-pubertal boys (9-11 years) and 22 men (18-30 years) performed ...
arxiv
Comparison of succinylcholine with two doses of rocuronium using a new method of monitoring neuromuscular block at the laryngeal muscles by surface laryngeal electromyography [PDF]
, 2000 Thomas M. Hemmerling +4 more
openalex +1 more source