Results 1 to 10 of about 11,357 (201)

Masseter Muscle Rigidity and Nondepolarizing Neuromuscular Blocking Agents [PDF]

Mayo Clinic Proceedings, 1997
Masseter muscle rigidity has been identified as a possible risk factor for malignant hyperthermia (MH) and is usually noted in children receiving intravenously administered succinylcholine chloride after mask induction with halothane. Nondepolarizing muscle relaxants are considered safe for persons susceptible to MH.
Gerald A. Gronert, Alison Albrecht, Denise J. Wedel   +2 more
semanticscholar   +5 more sources

Interaction Between Nondepolarizing Neuromuscular Blocking Agents and Inhalational Anesthetics

Anesthesia & Analgesia, 1989
Although many studies have presented data based on administration of nondepolarizing neuromuscular blocking agents to patients given inhalation anesthesia for 30-45 min, no data exist on the interaction in a clinical situation where the relaxant is administered immediately after the start of anesthesia.
Jantine M. Ket, Joseph Swen, Jo Hermans, Omar M. Rashkovsky, Sandor Agoston, Henk W. J. Koot   +5 more
semanticscholar   +6 more sources

The dose response effect of long-acting nondepolarizing neuromuscular blocking agents in children [PDF]

Canadian Anaesthetists’ Society Journal, 1984
Cumulative dose-response curves were constructed for pancuronium, metocurine, d-tubocurarine and gallamine in 56 children anaesthetized with thiopentone, N2O/O2 and narcotic. The dose response curves of the four relaxants did not deviate significantly from parallelism.
Nishan G. Goudsouzian, Jeevendra J. A. Martyn, Letty M. P. Liu, Hassan H. Ali   +3 more
semanticscholar   +6 more sources

Pharmacological Characteristics of the Inhibition of Nondepolarizing Neuromuscular Blocking Agents at Human Adult Muscle Nicotinic Acetylcholine Receptor [PDF]

Anesthesiology, 2009
Background Nondepolarizing neuromuscular blocking agents (NMBAs) are classic competitive-inhibitors at the muscle nicotinic acetylcholine receptor (nAChR). Although the fetal subtype muscle nAChR has been extensively studied at a molecular level, less is known about the interaction between nondepolarizing NMBAs and the human ...
Lars Eriksson, Malin Jonsson Fagerlund, Michael Dabrowski   +2 more
semanticscholar   +6 more sources

Effects of Neostigmine Reversal of Nondepolarizing Neuromuscular Blocking Agents on Postoperative Respiratory Outcomes [PDF]

Anesthesiology, 2014
AbstractBackground:We tested the hypothesis that neostigmine reversal of neuromuscular blockade reduced the incidence of signs and symptoms of postoperative respiratory failure.Methods:We enrolled 3,000 patients in this prospective, observer-blinded, observational study.
Sasaki, Nobuo, Meyer, Matthew J, Malviya, Sanjana A, Stanislaus, Anne B, MacDonald, Teresa, Doran, Mary E, Igumenshcheva, Arina, Hoang, Alan H, Eikermann, Matthias   +8 more
semanticscholar   +7 more sources

Increased Sensitivity to Depolarizing and Nondepolarizing Neuromuscular Blocking Agents in Young Rat Hemidiaphragms [PDF]

Anesthesiology, 2001
Background Newborn neuromuscular junctions are more sensitive to d-tubocurarine than more mature preparations. It is unclear whether the same modifications occur with newer nondepolarizing agents and depolarizing agent succinylcholine.
Richard Robitaille, François Donati, L. Philippe Fortier   +2 more
semanticscholar   +5 more sources

Pediatric Anesthetic Management of a Patient With an ALG-13 Gene Mutation, a Rare Congenital Disorder of Glycosylation. [PDF]

Clin Case Rep
ABSTRACT Congenital disorders of glycosylation are rare and present a challenge in management due to interactions with intraoperative medications. We present safe and successful anesthetic management of a pediatric patient with an ALG‐13 gene mutation.
Thakkar E, Iasiello JA, Cai SR, Hutton A.   +3 more
europepmc   +2 more sources

Chronic exposure to dexamethasone may not affect sugammadex reversal of rocuronium-induced neuromuscular blockade: an in vivo study on rats [PDF]

Anesthesia and Pain Medicine, 2023
Background Chronic glucocorticoid exposure is associated with resistance to nondepolarizing neuromuscular blocking agents. Therefore, we hypothesized that sugammadex-induced recovery would occur more rapidly in subjects exposed to chronic dexamethasone ...
Ha Yeon Park, Hey Ran Choi, Yong Beom Kim, Seok Kyeong Oh, Taehoon Kim, Hong Seuk Yang, Junyong In   +6 more
doaj   +2 more sources

A Review of Muscle Relaxants in Anesthesia in Patients with Neuromuscular Disorders Including Guillain-Barré Syndrome, Myasthenia Gravis, Duchenne Muscular Dystrophy, Charcot-Marie-Tooth Disease, and Inflammatory Myopathies. [PDF]

Med Sci Monit
Anesthesia management in neuromuscular diseases (NMDs) is a complex challenge, requiring careful preoperative evaluation, tailored treatment strategies, and vigilant perioperative monitoring.
Radkowski P, Oniszczuk H, Opolska J, Podlińska I, Pawluczuk M, Onichimowski D.   +5 more
europepmc   +2 more sources

Intubating conditions during rapid sequence induction with either rocuronium or suxamethonium in elderly patients. A randomised study. [PDF]

Acta Anaesthesiol Scand
Abstract Background During rapid sequence induction, either rocuronium 1.0 mg kg−1 or suxamethonium 1.0 mg kg−1 can be administered to facilitate endotracheal intubation. We hypothezised that rocuronium provided a larger proportion of excellent intubating conditions compared to suxamethonium in elderly patients.
Vested M, Creutzburg A, Meyhoff CS, Rovsing ML, Nielsen T, Rosa F, Aasvang EK, Mollerup H, Fuchs-Buder T, Rasmussen LS.   +9 more
europepmc   +2 more sources