Association between levobupivacaine and pancuronium. Interference in neuromuscular transmission and blockade in rats [PDF]
PURPOSE: To evaluate the effects of levobupivacaine on neuromuscular transmission and neuromuscular blockade produced by pancuronium in vitro. METHODS: Thirty rats were distributed into groups (n = 5) according to the drug used alone or in combination:
Vanessa Henriques Carvalho +5 more
doaj +7 more sources
Background: The utility of Neuromuscular monitoring (NMT) has not been studied in Indian scenario till date. We did a survey to evaluate the knowledge, attitude, practices of NMT among Indian anesthesiologists. Methods: A questionnaire-based google form
Sonal Goyal, Bhavna Gupta
doaj +1 more source
Neuromuscular blockers and their reversal: have we finally found the on-off switches?
Background A nondepolarizing neuromuscular blocking agent (NMBA) with a succinylcholine-like quick onset and offset has been the holy grail of the science of neuromuscular blockade.
Shagun Bhatia Shah +3 more
doaj +1 more source
Masseter Muscle Rigidity and Nondepolarizing Neuromuscular Blocking Agents [PDF]
Masseter muscle rigidity has been identified as a possible risk factor for malignant hyperthermia (MH) and is usually noted in children receiving intravenously administered succinylcholine chloride after mask induction with halothane. Nondepolarizing muscle relaxants are considered safe for persons susceptible to MH.
A, Albrecht, D J, Wedel, G A, Gronert
openaire +2 more sources
Chronic exposure to dexamethasone may not affect sugammadex reversal of rocuronium-induced neuromuscular blockade: an in vivo study on rats [PDF]
Background Chronic glucocorticoid exposure is associated with resistance to nondepolarizing neuromuscular blocking agents. Therefore, we hypothesized that sugammadex-induced recovery would occur more rapidly in subjects exposed to chronic dexamethasone ...
Ha Yeon Park +6 more
doaj +1 more source
Effects of adenosine receptor agonist on the rocuroniuminduced neuromuscular block and sugammadex-induced recovery [PDF]
Background Several types of receptors are found at neuromuscular presynaptic membranes. Presynaptic inhibitory A1 and facilitatory A2A receptors mediate different modulatory functions on acetylcholine release. This study investigated whether adenosine A1
Yong Beom Kim +7 more
doaj +1 more source
Pharmacodynamic interactions between muscle relaxants and other medications in practice of anesthesia [PDF]
Knowledge of drug interactions is an essential element of medical practice. Along with the increasing occurrence of multimorbidity and the associated multi-drug use, the number of possible combinations of preparations is constantly rising.
Paweł Radkowski, Rafał Marek Okoński
doaj +1 more source
Factors that affect the onset of action of non-depolarizing neuromuscular blocking agents [PDF]
Neuromuscular blockade plays an important role in the safe management of patient airways, surgical field improvement, and respiratory care. Rapid-sequence induction of anesthesia is indispensable to emergency surgery and obstetric anesthesia, and its ...
Yong Byum Kim +2 more
doaj +1 more source
Background: Quantitative train-of-four (TOF) monitoring remains essential in optimizing anesthetic outcomes by assessing the depth and recovery from neuromuscular blockade. Despite this, residual neuromuscular blockade, defined as a TOF ratio
Kwaku Owusu-Bediako +3 more
doaj +1 more source
A fresh look at paralytics in the critically ill: real promise and real concern. [PDF]
Neuromuscular blocking agents (NMBAs), or "paralytics," often are deployed in the sickest patients in the intensive care unit (ICU) when usual care fails.
Kenyon, Nicholas J +2 more
core +2 more sources

