Results 1 to 10 of about 1,612 (159)
Pediatric Anesthetic Management of a Patient With an ALG-13 Gene Mutation, a Rare Congenital Disorder of Glycosylation. [PDF]
ABSTRACT Congenital disorders of glycosylation are rare and present a challenge in management due to interactions with intraoperative medications. We present safe and successful anesthetic management of a pediatric patient with an ALG‐13 gene mutation.
Thakkar E+3 more
europepmc +2 more sources
Intubating conditions during rapid sequence induction with either rocuronium or suxamethonium in elderly patients. A randomised study. [PDF]
Abstract Background During rapid sequence induction, either rocuronium 1.0 mg kg−1 or suxamethonium 1.0 mg kg−1 can be administered to facilitate endotracheal intubation. We hypothezised that rocuronium provided a larger proportion of excellent intubating conditions compared to suxamethonium in elderly patients.
Vested M+9 more
europepmc +2 more sources
Masseter Muscle Rigidity and Nondepolarizing Neuromuscular Blocking Agents [PDF]
Masseter muscle rigidity has been identified as a possible risk factor for malignant hyperthermia (MH) and is usually noted in children receiving intravenously administered succinylcholine chloride after mask induction with halothane. Nondepolarizing muscle relaxants are considered safe for persons susceptible to MH.
Gerald A. Gronert+2 more
openaire +3 more sources
Neuromuscular Blockade Monitoring: Having It but Knowing When Not to Trust It [PDF]
Butyrylcholinesterase (BChE) is an enzyme involved in the degradation of depolarizing and non-depolarizing neuromuscular blocking agents (NMBA), such as succinylcholine and mivacurium, respectively. Its deficiency is inherited or acquired, and results in
Campos, Matilde+3 more
core +1 more source
Key Clinical Message The perioperative control of ammonia, reduction of stress, and administration of drugs tolerated in type 1 citrullinemia and Brugada pattern allowed the successful and uneventful management of general anesthesia in the study patient.
Fabio Dell’Olio+8 more
wiley +1 more source
Key Clinical Message Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a genetic disorder in which catecholamine release during exercise or emotional stress cause fatal tachyarrhythmias. In this paper, we discuss methods to minimize the sympathetic stimulation that can occur during the perioperative period in patients undergoing left ...
Kyung‐Hwa Kwak+4 more
wiley +1 more source
A novel RYR1 variant in an infant with a unique fetal presentation of central core disease
Abstract Ryanodine receptor type 1‐related disorder (RYR1‐RD) is the most common subgroup of congenital myopathies with a wide phenotypic spectrum ranging from mild hypotonia to lethal fetal akinesia. Genetic testing for myopathies is imperative as the diagnosis informs counseling regarding prognosis and recurrence risk, treatment options, monitoring ...
Elizabeth K. Baker+6 more
wiley +1 more source
This consensus statement summarizes the most important recommendations concerning anaesthesia in patients with neuromuscular disorders. Abstract Background and purpose Patients with neuromuscular conditions are at increased risk of suffering perioperative complications related to anaesthesia.
Luuk R. van den Bersselaar+21 more
wiley +1 more source
A fresh look at paralytics in the critically ill: real promise and real concern. [PDF]
Neuromuscular blocking agents (NMBAs), or "paralytics," often are deployed in the sickest patients in the intensive care unit (ICU) when usual care fails.
Kenyon, Nicholas J+2 more
core +2 more sources
Abstract Background The prevalence and risk factors for residual neuromuscular blockade in children remain poorly characterized. We hypothesize that specific patient and anesthetic risk factors may be associated with the administration of additional reversal in children following initial reversal of rocuronium with neostigmine.
Susan R. Vishneski+8 more
wiley +1 more source