The dose response effect of long-acting nondepolarizing neuromuscular blocking agents in children [PDF]
Canadian Anaesthetists’ Society Journal, 1984 Cumulative dose-response curves were constructed for pancuronium, metocurine, d-tubocurarine and gallamine in 56 children anaesthetized with thiopentone, N2O/O2 and narcotic. The dose response curves of the four relaxants did not deviate significantly from parallelism.
Nishan G. Goudsouzian +3 more
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Association between levobupivacaine and pancuronium. Interference in neuromuscular transmission and blockade in rats [PDF]
Acta Cirúrgica Brasileira, 2016 PURPOSE: To evaluate the effects of levobupivacaine on neuromuscular transmission and neuromuscular blockade produced by pancuronium in vitro. METHODS: Thirty rats were distributed into groups (n = 5) according to the drug used alone or in combination:
Vanessa Henriques Carvalho +5 more
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Increased Sensitivity to Depolarizing and Nondepolarizing Neuromuscular Blocking Agents in Young Rat Hemidiaphragms [PDF]
Anesthesiology, 2001 Background Newborn neuromuscular junctions are more sensitive to d-tubocurarine than more mature preparations. It is unclear whether the same modifications occur with newer nondepolarizing agents and depolarizing agent succinylcholine.
Louis‐Philippe Fortier +2 more
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Pharmacological Characteristics of the Inhibition of Nondepolarizing Neuromuscular Blocking Agents at Human Adult Muscle Nicotinic Acetylcholine Receptor [PDF]
Anesthesiology, 2009 Background Nondepolarizing neuromuscular blocking agents (NMBAs) are classic competitive-inhibitors at the muscle nicotinic acetylcholine receptor (nAChR). Although the fetal subtype muscle nAChR has been extensively studied at a molecular level, less is known about the interaction between nondepolarizing NMBAs and the human ...
Malin Jonsson Fagerlund +2 more
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Effects of Neostigmine Reversal of Nondepolarizing Neuromuscular Blocking Agents on Postoperative Respiratory Outcomes [PDF]
Anesthesiology, 2014 AbstractBackground:We tested the hypothesis that neostigmine reversal of neuromuscular blockade reduced the incidence of signs and symptoms of postoperative respiratory failure.Methods:We enrolled 3,000 patients in this prospective, observer-blinded, observational study.
Nobuo Sasaki +8 more
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Preclinical Pharmacology in the Rhesus Monkey of CW 1759-50, a New Ultra-short Acting Nondepolarizing Neuromuscular Blocking Agent, Degraded and Antagonized by L-Cysteine [PDF]
Anesthesiology, 2018 Abstract Editor’s Perspective What We Already Know about This Topic What This Article Tells Us That Is New Background Structure–activity studies were performed to identify a new neuromuscular blocking agent retaining ...
John J. Savarese +8 more
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Nondepolarizing Neuromuscular Blocking Agents Exacerbate Inflammation Response by Antagonizing α7 Nicotinic Acetylcholine Receptors [PDF]
Journal of Anesthesia and Translational Medicine, 2022 Yang Hu +5 more
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Effectiveness versus Efficacy of Calabadion and Sugammadex for Nondepolarizing Neuromuscular Blocking Agent Reversal [PDF]
Anesthesiology, 2016 Grace Lim, Douglas Landsittel
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Neostigmine: How Much Is Necessary for Patients Who Receive a Nondepolarizing Neuromuscular Blocking Agent? [PDF]
Anesthesiology, 2009 Cynthia A. Lien
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