Results 21 to 30 of about 1,162 (153)
Neuromuscular blockers and their reversal: have we finally found the on-off switches?
Ain Shams Journal of Anesthesiology, 2021 Background A nondepolarizing neuromuscular blocking agent (NMBA) with a succinylcholine-like quick onset and offset has been the holy grail of the science of neuromuscular blockade.
Shagun Bhatia Shah +3 more
doaj +1 more source
Chronic exposure to dexamethasone may not affect sugammadex reversal of rocuronium-induced neuromuscular blockade: an in vivo study on rats [PDF]
Anesthesia and Pain Medicine, 2023 Background Chronic glucocorticoid exposure is associated with resistance to nondepolarizing neuromuscular blocking agents. Therefore, we hypothesized that sugammadex-induced recovery would occur more rapidly in subjects exposed to chronic dexamethasone ...
Ha Yeon Park +6 more
doaj +1 more source
Effects of adenosine receptor agonist on the rocuroniuminduced neuromuscular block and sugammadex-induced recovery [PDF]
Korean Journal of Anesthesiology, 2018 Background Several types of receptors are found at neuromuscular presynaptic membranes. Presynaptic inhibitory A1 and facilitatory A2A receptors mediate different modulatory functions on acetylcholine release. This study investigated whether adenosine A1
Yong Beom Kim +7 more
doaj +1 more source
Clinical Case Reports, Volume 11, Issue 8, August 2023., 2023 Key Clinical Message The perioperative control of ammonia, reduction of stress, and administration of drugs tolerated in type 1 citrullinemia and Brugada pattern allowed the successful and uneventful management of general anesthesia in the study patient.
Fabio Dell’Olio +8 more
wiley +1 more source
Pharmacodynamic interactions between muscle relaxants and other medications in practice of anesthesia [PDF]
Farmacja Polska, 2023 Knowledge of drug interactions is an essential element of medical practice. Along with the increasing occurrence of multimorbidity and the associated multi-drug use, the number of possible combinations of preparations is constantly rising.
Paweł Radkowski, Rafał Marek Okoński
doaj +1 more source
Clinical Case Reports, Volume 11, Issue 7, July 2023., 2023 Key Clinical Message Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a genetic disorder in which catecholamine release during exercise or emotional stress cause fatal tachyarrhythmias. In this paper, we discuss methods to minimize the sympathetic stimulation that can occur during the perioperative period in patients undergoing left ...
Kyung‐Hwa Kwak +4 more
wiley +1 more source
Saudi Journal of Anaesthesia, 2022 Background: Quantitative train-of-four (TOF) monitoring remains essential in optimizing anesthetic outcomes by assessing the depth and recovery from neuromuscular blockade. Despite this, residual neuromuscular blockade, defined as a TOF ratio
Kwaku Owusu-Bediako +3 more
doaj +1 more source
A novel RYR1 variant in an infant with a unique fetal presentation of central core disease
American Journal of Medical Genetics Part A, Volume 191, Issue 6, Page 1646-1651, June 2023., 2023 Abstract Ryanodine receptor type 1‐related disorder (RYR1‐RD) is the most common subgroup of congenital myopathies with a wide phenotypic spectrum ranging from mild hypotonia to lethal fetal akinesia. Genetic testing for myopathies is imperative as the diagnosis informs counseling regarding prognosis and recurrence risk, treatment options, monitoring ...
Elizabeth K. Baker +6 more
wiley +1 more source
Factors that affect the onset of action of non-depolarizing neuromuscular blocking agents [PDF]
Korean Journal of Anesthesiology, 2017 Neuromuscular blockade plays an important role in the safe management of patient airways, surgical field improvement, and respiratory care. Rapid-sequence induction of anesthesia is indispensable to emergency surgery and obstetric anesthesia, and its ...
Yong Byum Kim +2 more
doaj +1 more source
Journal of Anaesthesiology Clinical Pharmacology, 2013 Evaluation of the degree of neuromuscular blockade by the surgeon using clinical criteria alone is unreliable. We report a case of prolonged neuromuscular blockade lasting 5.5 h, where an additional intra-operative dose of neuromuscular relaxant was ...
James J Lamberg, Joseph F Answine
doaj +1 more source