Emerging considerations in the reversal of neuromuscular blockade and residual block [PDF]
Incomplete recovery following reversal of neuromuscular blockade can present as a clinical problem in surgical patients. Emerging pharmacologic solutions may prevent such adverse outcomes in the future.
CHRISTOPHER J. JANKOWSKI+2 more
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Central venous catheters (CVCs) are often used intraoperatively for large volume resuscitation and the administration of vasoactive medications. Many of these catheters are impregnated with antimicrobials to prevent infection but independent reports of anaphylaxis directly following catheter placement have been increasing. Here, we report the case of a
Yusuf Ali+4 more
wiley +1 more source
Impact of anesthesia drugs on digestive motility measurements in humans: A systematic review
Abstract Background and Purpose Measurement of gastro‐intestinal motility is increasingly performed under general anesthesia during endoscopic or surgical procedures. The aim of the present study was to review the impact of different anesthetic agents on digestive motility measurements in humans.
Domitille Renard+3 more
wiley +1 more source
A comparison of the differential effects of atracurium and/or lidocaine on succinylcholine-induced postoperative myalgia [PDF]
It is well documented that the administration of succinylcholine (SCh), also known as suxamethonium, with general anesthesia causes muscle fasciculations, which may cause severe postoperative myalgia.
Campbell, Tonya Lynn DeWitt
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Using General Anesthesia plus Muscle Relaxant in a Patient with Spinal Muscular Atrophy Type IV: A Case Report [PDF]
Spinal muscular atrophy (SMA) is a rare genetic disease characterized by degeneration of spinal cord motor neurons, which results in hypotonia and muscle weakness. Patients with type IV SMA often have onset of weakness from adulthood.
Liu, Xiu-Fen, Ma, Daqing, Wang, Dong-Xin
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Aims Residual neuromuscular blockade has been linked to pulmonary complications in the postoperative period. This study aimed to determine whether sugammadex was associated with a lower risk of postoperative pulmonary complications (PPCs) compared with neostigmine.
Aolin Ren+8 more
wiley +1 more source
In the Surgical Patient Requiring Neuromuscular Blockade, Is There an Increased Incidence of Postoperative Adverse Respiratory Events with Rocuronium or Vecuronium? [PDF]
It is estimated that up to 45% of surgical patients will have postoperative residual neuromuscular blockade (NMB) upon arrival to the postanesthesia care unit (PACU), and incomplete recovery can impair upper airway function and contribute to adverse ...
Boos, Martha Claudine
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Open-Globe Eye Injuries and Choice of Muscle Relaxant: A Review of the Evidence [PDF]
A goal of treatment of open-globe eye injuries is preventing rises in intraocular pressure and the resulting loss of vitreous humor fluid from the eye globe.
Benoit, BSN, RRNA, Joelle+1 more
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Peripheral nervous system and neuromuscular disorders in the emergency department: A review
Abstract Introduction Acute presentations and emergencies in neuromuscular disorders (NMDs) often challenge clinical acumen. The objective of this review is to refine the reader's approach to history taking, clinical localization and early diagnosis, as well as emergency management of neuromuscular emergencies.
Ajith Sivadasan+3 more
wiley +1 more source
Abstract The rapid reversal of deep neuromuscular blockade (NMB) is important but remains challenging. This study aimed to evaluate the efficacy and safety of adamgammadex versus sugammadex in reversing deep rocuronium‐induced NMB. This multicenter, randomized, phase IIb study included 80 patients aged 18–64 years, American Society of Anesthesiologists
Yanhua Zhao+10 more
wiley +1 more source