Results 71 to 80 of about 6,009,896 (230)

Data‐Independent Acquisition Mass Spectrometry in Tumor Classification and Cancer Biomarker Research

Mass Spectrometry Reviews, EarlyView.
Abstract Cancer treatment is far from optimal also because current classification systems do not reflect the complex molecular status of the tumor and its phenotype in sufficient detail. To construct molecular tumor classifiers, omics tools provide complex molecular data reflecting many aspects from genotype to phenotype.
Jan Simonik, Petr Lapcik, Pavla Bouchalova, Pavel Bouchal   +3 more
wiley   +1 more source

Hubungan Kadar Neuron-Specific Enolase Serum dengan Mortalitas pada Sepsis Neonatorum

Sari Pediatri, 2016
Latar belakang. Sepsis neonatorum menyebabkan respons inflamasi berlebih sehingga terjadi kerusakan sawar darah otak, disfungsi serebrovaskular dan oksigenasi, gangguan neurotransmiter, degenerasi sel neuron, edema serebral yang berakhir pada kematian ...
Ricky Hartanto, Nurhayati Masloman, Johnny Rompis, Rocky Wilar   +3 more
doaj   +1 more source

Neuron-Specific Enolase Evaluation in Patients with Neuroblastoma

Tumor Biology, 1998
Neuron-specific enolase (NSE) may be of interest for the prognostic evaluation and follow-up surveillance in patients with neuroblastoma. We evaluated NSE levels in 80 patients with neuroblastoma. The marker correlated with stage (in stage 1 patients, the median NSE level was 9.9 ng/ml, in stage 2, 45.1 ng/ml, in stage 3, 49 ng/ml, in stage 4, 93.9 ng ...
S, Massaron, E, Seregni, R, Luksch, M, Casanova, C, Botti, L, Ferrari, A, Martinetti, S N, Molteni, F F, Bellani, E, Bombardieri   +9 more
openaire   +2 more sources

Proteomics of Nitrotyrosine: Integrating Mass Spectrometry and Immunodetection in Redox‐Driven Pathology

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Nitrooxidative stress, driven by excess reactive nitrogen species like peroxynitrite, contributes to the pathogenesis of many chronic diseases. Among its molecular footprints, 3‐nitrotyrosine (3NT) has emerged as a biologically relevant marker of protein nitration.
Brîndușa Alina Petre
wiley   +1 more source

Development and analytical performance evaluation of an automated chemiluminescent immunoassay for pro-gastrin releasing peptide (ProGRP) [PDF]

, 2009
Background: Pro-gastrin releasing peptide ( ProGRP) concentrations in blood play an important role in the diagnosis and treatment of patients with small cell lung cancer (SCLC).
Patil, Rahul D., Dowell, Barry L., Iizuka, Masayuki, Yamaguchi, Ken, Chan, Sabrina S., Kinukawa, Hideki, Chan, Daniel W., Hofmann, Karin, Stieber, Petra, Sakurai, Yousuke, Yoshimura, Toru, Matsuoka, Yoshiharu, Sokoll, Lori, Scheuer, Cornelia, Saegusa, Haruhisa, Fujita, Kenju, Beligere, Gangamani S., Elliott, Debra   +17 more
core   +1 more source

Ion Activation Methods for Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Mass spectrometry (MS) has emerged as a premier method used to characterize the sequences of proteins. Top‐down proteomics aims to capture the multiple sources of structural diversity reflected in proteins, such as those that arise from alternative RNA splicing events or the addition of post‐translational modifications. Tandem MS (i.e., MS/MS)
Jada N. Walker, Jennifer S. Brodbelt
wiley   +1 more source

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág, Krisztián Márk Karvaly, Alexandra Molnár, Mirjam Balbisi, Júlia Németh, Lilla Turiák   +5 more
wiley   +1 more source

Neuron specific enolase as a possible indicator of neuron damage in children with acute meningitis

Zaporožskij Medicinskij Žurnal, 2018
Acute meningitis in children is a common cause of complications and leads to developmental disabilities. That is the reason why it is important to look for possible markers that indicate nerve tissue damage for early diagnosis, their prevention and ...
L. V. Pypa, R. V. Svistilnik, G. S. Moskovko, Yu. M. Lysytsia, , M. M. Murhina   +4 more
doaj   +1 more source

A bioinformatics approach to the development of immunoassays for specified risk material in canned meat products [PDF]

, 2009
A bioinformatics approach to developing antibodies to specific proteins has been evaluated for the production of antibodies to heat-processed specified risk tissues from ruminants (brain and eye tissue).
Danks, C., Hemetsberger, C., Stones, R., Baumgartner, S., Lubbe, W., Reece, P., Smits, N.G.E., Bremer, M.G.E.G., Tomkies, V.   +8 more
core   +1 more source

Harnessing Aggregation‐Induced Emission for Advanced Disease Diagnosis: Mechanisms, Strategies and Future Perspectives

Medicine Bulletin, EarlyView.
The figure was created in BioRender.com. ABSTRACT Accurate and early diagnosis remains a key challenge in modern disease management. Conventional diagnostic methods often suffer from limitations in sensitivity, spatial resolution, and practical usability.
Zizhuo Du, Li Song, Xingrui Chen, Jun Jing, Yingchen Wang, Yue Jiang, Jiahui Gao, Dan Li, Feiran Xie, Peihong Xiao, Ben Zhong Tang   +10 more
wiley   +1 more source