Results 81 to 90 of about 6,009,896 (230)

Biomarcadores na encefalopatia séptica: revisão sistemática dos estudos clínicos Biomarkers in septic encephalopathy: a systematic review of clinical studies

open access: yesRevista Brasileira de Terapia Intensiva, 2013
OBJETIVO: O objetivo deste estudo foi revisar sistematicamente a importância da enolase específica neuronal e S100B para diagnóstico e monitorização da encefalopatia séptica.
Paula Veriato Zenaide   +1 more
doaj  

Base line characteristics stratified by neuron-specific enolase (NSE) -quartiles in 685 included patients.

open access: yes, 2017
Base line characteristics stratified by neuron-specific enolase (NSE) -quartiles in 685 included patients.
Michael Wanscher (706395)   +20 more
core   +1 more source

Carbon dots in electrochemiluminescence: Mechanisms, interface engineering, and bioanalytical applications

open access: yesResponsive Materials, EarlyView.
Carbon dots are emerging as versatile electrochemiluminescent nanomaterials whose structure, surface states, and interfacial design jointly determine ECL pathways and performance. This review highlights how mechanistic understanding and materials engineering enable programmable CD‐ECL systems for bioanalysis, imaging, and future intelligent analytical ...
Yuhan Zhao, Zixuan Chen, Jun‐Jie Zhu
wiley   +1 more source

Multifunctional roles of γ-enolase in the central nervous system: more than a neuronal marker

open access: yesCell & Bioscience
Enolase, a multifunctional protein with diverse isoforms, has generally been recognized for its primary roles in glycolysis and gluconeogenesis. The shift in isoform expression from α-enolase to neuron-specific γ-enolase extends beyond its enzymatic role.
Selena Horvat, Janko Kos, Anja Pišlar
doaj   +1 more source

Targeting the CD47–SIRPα phagocytic checkpoint in cancer: Biology, translational opportunities, and next‐generation therapeutic strategies

open access: yesSmart Molecules, EarlyView.
The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou   +4 more
wiley   +1 more source

Changes neuron-specific enolase and protein S100 in the acute period of tick-borne infections in children

open access: yesБюллетень сибирской медицины, 2010
We evaluated clinical and laboratory findings in 86 patients of 4—16 years old. Data showed that in all forms of tick-borne infections S100 concentration increased.
G. Yu. Galiyeva   +2 more
doaj   +1 more source

Electrochemical aptasensors for ultrasensitive multiplexed detection: Towards a new era of precision diagnostics and environmental monitoring

open access: yesVIEW, EarlyView.
Electrochemical aptasensors are emerging as powerful platforms for precision diagnostics and environmental monitoring, owing to their high selectivity, programmability and compatibility with miniaturised systems. However, their broader application is constrained by limited signal intensity and challenges in reliable multiplexed detection.
Azadeh Abdi   +5 more
wiley   +1 more source

Predictive values of neuron-specific enolase (NSE) with a low false-positive rate.

open access: yes, 2017
Predictive values of neuron-specific enolase (NSE) with a low false-positive rate.
Michael Wanscher (706395)   +20 more
core   +1 more source

From patient to tumor organoid: Culture protocol choice controls glioblastoma tumor architecture and identity

open access: yesBrain Pathology, EarlyView.
How glioblastoma organoids are made shapes what they become. Fragment‐based cultures preserve extracellular matrix networks, cellular diversity, and primary tumor identity, whereas dissociation‐based cultures shift toward growth‐adapted states and simplified microenvironments. Abstract Patient‐derived tumor organoids are widely used in cancer research,
Jana Slovackova   +11 more
wiley   +1 more source

Shared dysregulation of complement and phosphorylation pathways in the cerebrospinal fluid of encephalitis, Aicardi–Goutières syndrome, and autism

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Abstract Aim To identify shared and disorder‐specific molecular alterations across encephalitis, Aicardi–Goutières syndrome (AGS), and autism spectrum disorder (ASD) using cerebrospinal fluid (CSF) proteomics. Method In this cross‐sectional case–control study, mass‐spectrometry‐based proteomics was performed on archived CSF samples collected between ...
Omar H. Shadid   +8 more
wiley   +1 more source

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