Results 101 to 110 of about 24,763 (225)

Early Versus Late Wake‐Up Call After Out‐Of‐Hospital Cardiac Arrest: Protocol for a Multicenter Randomized Comparison Within the Danish Out‐of‐Hospital Cardiac Arrest (DANOHCA) Trial

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 6, July 2026.
ABSTRACT Background Survivors of out‐of‐hospital cardiac arrest (OHCA) who remain comatose after return of spontaneous circulation are routinely sedated and mechanically ventilated during early post‐resuscitation care. Although prolonged sedation has traditionally been considered necessary, contemporary normothermia‐based temperature control allows ...
Anders Morten Grejs, Jesper Kjaergaard, Jo Bønding Andreasen, Bodil Steen Rasmussen, Christian Hassager, Martin Abild Stengaard Meyer, Lars Peter Kloster Andersen, Henrik Schmidt, Simon Moelstroem, Sören Möller, Christhopher Torp, Steffen Christensen, Jacob Eifer Moeller   +12 more
wiley   +1 more source

Release of erythropoietin and neuron-specific enolase after breath holding in competing free divers

, 2015
Free diving is associated with extreme hypoxia. This study evaluated the combined effect of maximal static breath holding and underwater swimming on plasma biomarkers of tissue hypoxemia: erythropoietin, neuron-specific enolase and S100B, C-reactive ...
Olsen, Niels Vidiendal, Kjeld, Thomas, Gøtze, Jens Peter, Jattu, T, Secher, Niels H., Nielsen, Henrik   +5 more
core   +1 more source

Rapid generation of prion disease models using AAV‐delivered PrP variants in knockout mice

Brain Pathology, Volume 36, Issue 4, July 2026.
We developed a rapid AAV‐based system to generate prion disease models in weeks rather than months. Following systemic AAV9P31 delivery of modified PrP to knockout mice, we achieved brain‐wide expression and successful propagation of both classical (RML) and atypical (GSS‐A117V) prion strains.
Maitena San‐Juan‐Ansoleaga, Eva Fernández‐Muñoz, Jorge M. Charco, Enric Vidal, Diego Herrero‐Martínez, Josu Galarza‐Ahumada, Cristina Sampedro‐Torres‐Quevedo, Samanta Giler, Mariví Geijo, Gloria González‐Aseguinolaza, Hasier Eraña, Joaquín Castilla   +11 more
wiley   +1 more source

Neuron Specific Enolase and Serum Electrolytes in Comatose Patients

Background: Coma is a profound state of unconsciousness in which the patient cannot be roused by external stimuli. The metabolic fingerprint of comatose patients is essential to identify the underlying molecular pathways and to use as a basis for ...
Beden, Murtada Wafi
core   +1 more source

S-100 protein and neuron-specific enolase in cerebrospinal fluid and serum: markers of cell damage in human central nervous system.

, 1987
The development of a radioimmunoassay for S-100 protein is described. This method was used in combination with a recently developed radioimmunoassay for neuron-specific enolase in cerebrospinal fluid and serum from 47 patients with cerebral infarction ...
I Mendel-Hartvig, H G Hårdemark, J Gustafsson, T Esscher, L Persson, G Rundström, S Påhlman   +6 more
core   +1 more source

Multi‐Omics Landscape of Paraspinal Muscles in Spinal Muscular Atrophy With Scoliosis

Journal of Cellular and Molecular Medicine, Volume 30, Issue 13, July 2026.
ABSTRACT Most spinal muscular atrophy (SMA) patients develop severe scoliosis by late adolescence. Given that the paraspinal muscles—particularly the multifidus—are indispensable for maintaining spinal stability, their site‐specific multi‐omics characteristics in SMA remain insufficiently defined. Herein, integrated multi‐omics sequencing was performed
Zhen Wang, Junduo Zhao, Xu'an Huang, Weiyun Chen, Jianxiong Shen   +4 more
wiley   +1 more source

Mechanisms and integrative machine learning approaches to blood–brain barrier biomarker profiling for personalized ischemic stroke management

Physiological Reports, Volume 14, Issue 13, July 2026.
Abstract Ischemic stroke remains a leading cause of death and disability worldwide, with blood–brain barrier (BBB) disruption playing a central role in vasogenic edema, neuroinflammation, hemorrhagic transformation, and secondary neuronal injury. The BBB is a specialized neurovascular unit composed of endothelial tight junctions, pericytes, astrocytes,
John Nzobokela, Lweendo Muchaili, Joy Kaluba Mangimela, Annet Kirabo, Sepiso K. Masenga   +4 more
wiley   +1 more source

Molecular–clinical characteristics and treatment outcomes in 163 metastatic colorectal neuroendocrine carcinomas with a comparison to colorectal adenocarcinomas

International Journal of Cancer, Volume 158, Issue 12, Page 3217-3231, 15 June 2026.
What's new? Colorectal neuroendocrine carcinoma (CR‐NEC) is a rare digestive neuroendocrine neoplasm that frequently exhibits an adenocarcinoma component. Nonetheless, the underlying biology of CR‐NEC remains poorly understood. This study examined molecular and clinical features and palliative chemotherapy outcomes of metastatic CR‐NEC, with comparison
Siren Morken, Seppo W. Langer, Geir Olav Hjortland, Anna Sundlöv, Eva Hofsli, Morten Ladekarl, Elizaveta Tabaksblat, Lene Weber Vestermark, Johanna Svensson, Ulrich Knigge, Luís Nunes, Bengt Glimelius, Per Pfeiffer, Kristine Aasebø, Jörg Assmus, Erik Vassella, Inger Marie Bowitz Lothe, Anne Couvelard, Aurel Perren, Stian Knappskog, Halfdan Sorbye   +20 more
wiley   +1 more source

Clinical and prognostic significance of tumor markers cytokeratin 19 fragment, carcinoembryonic antigen, and neuron-specific enolase in lung cancer

, 2005
OBJECTIVE: To evaluate the clinical and prognostic significance of the tumor markers cytokeratin 19 fragment, carcinoembryonic antigen and neuron-specific enolase in lung cancer patients.
Malakauskas, Kęstutis, Fischer, Jürgen Richard, Muley, Thomas, Žemaitis, Marius, Sakalauskas, Raimundas, Lahm, Harald   +5 more
core  

Neuron-specific enolase and S100B protein in children with carbon monoxide poisoning: children are not just small adults

, 2013
Introduction: The aim of this study was to evaluate the role of S100B protein and neuron-specific enolase (NSE) in children with carbon monoxide (CO ...
Akelma, Fatma Kavak, Ozdemir, Osman, Razi, Cem Hasan, ABACI, AYHAN, Kislal, Fatih Mehmet, Akin, Okhan, Celik, Aydin, Akelma, Ahmet Zulfikar   +7 more
core   +1 more source