Results 131 to 140 of about 1,818,525 (389)

Selective enhancement of fear extinction by inhibiting neuronal adenylyl cyclase 1 (AC1) in aged mice

open access: yesMolecular Brain
Adenylyl cyclase 1 (AC1) is a selective subtype of ACs, which is selectively expressed in neurons. The activation of AC1 is activity-dependent, and AC1 plays an important role in cortical excitation that contributes to chronic pain and related emotional ...
Wantong Shi   +5 more
doaj   +1 more source

The Condition of the Vasomotor Neurons in Shock [PDF]

open access: green, 1903
W. T. Porter, William C. Quinby
openalex   +1 more source

KIF5A p.Pro986Leu Risk Variant and Accelerated Progression of Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study explored the impact of KIF5A rs113247976 (p.Pro986Leu), a risk allele for amyotrophic lateral sclerosis (ALS), on phenotypic variability in two Italian ALS cohorts (discovery, n = 865; replication, n = 1174). The minor allele (T) frequency was 0.015.
Arianna Manini   +24 more
wiley   +1 more source

Microtubules: The neuronic system of the neurons?

open access: yes, 1997
20 pages LATEX, no figures; Invited talk by D.V.N.
Mavromatos, N. E., Nanopoulos, D. V.
openaire   +2 more sources

CNS Mitochondria‐Derived Vesicle in Blood: Potential Biomarkers for Brain Mitochondria Dysfunction

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial dysfunction is a hallmark of neurodegenerative diseases like Alzheimer's (AD) and Parkinson's (PD). Our goal was to develop practical, noninvasive methods to assess mitochondrial status through the detection of mitochondria‐derived vesicles (MDVs).
Qi Liu   +12 more
wiley   +1 more source

Real-time visualization of oxidative stress-mediated neurodegeneration of individual spinal motor neurons in vivo

open access: yesRedox Biology, 2018
Generation of reactive oxygen species (ROS) has been shown to be important for many physiological processes, ranging from cell differentiation to apoptosis. With the development of the genetically encoded photosensitiser KillerRed (KR) it is now possible
Isabel Formella   +8 more
doaj  

Super Neurons

open access: yesIEEE Transactions on Emerging Topics in Computational Intelligence
Self-Organized Operational Neural Networks (Self-ONNs) have recently been proposed as new-generation neural network models with nonlinear learning units, i.e., the generative neurons that yield an elegant level of diversity; however, like its predecessor, conventional Convolutional Neural Networks (CNNs), they still have a common drawback: localized ...
Serkan Kiranyaz   +7 more
openaire   +4 more sources

A PANoptosis‐Based Signature for Survival and Immune Predication in Glioblastoma Multiforme

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PANoptosis is a concept of total cell death characterized by pyroptosis, apoptosis, and necroptosis. We aimed to explore the clinical significance of PANoptosis‐related genes (PARGs) in glioblastoma multiforme (GBM). Methods Expression profiles of GBM were downloaded from the XENA database as a training dataset to construct a ...
Jun Yang   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy