Results 141 to 150 of about 585,120 (318)

Neuron With Sliding-Mode Control For Nonlinear Systems [PDF]

, 2012
[[abstract]]In this paper, we present a sliding-mode control scheme for nonlinear systems which integrates an auto-tuning single neuron. The single neuron with an adaptive SMC controller is used to achieve adaptation.
陳永欽;Chen, Yeong-Chin
core  

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Gut transit and gut microbiome changes occur prior to the onset of motor impairment in a mouse model of Machado-Joseph disease

Neurobiology of Disease
We previously identified microbial shifts prior to the onset of motor and neurological symptoms within a mouse model of the fatal neurodegenerative disease Machado-Joseph disease (MJD).
Vasilisa Zvyagina, Andrea Kuriakose, Ignacio Simó, Julia Y. Kam, Prapti Chakraborty, Katherine J. Robinson, Anastasiya Potapenko, Maxinne Watchon, Ian T. Paulsen, Hasinika K.A.H. Gamage, Angela S. Laird   +10 more
doaj   +1 more source

Spintronic FitzHugh–Nagumo spiking neuron device for spiking neural networks [PDF]

Spintronic-based neuron devices for neural network hardware are gaining increasing attention. However, the majority of these devices are designed to replicate a highly simplified neuronal model known as the leaky integrate-and-fire (LIF) neuron.
Meng Tang, Daniel N. Rahimi, Setti, Gianluca, Rahimi, Daniel N., Divyanshu, Divyanshu, Gianluca Setti, Divyanshu Divyanshu, Lone, Aijaz H, Tang, Meng, Amara, Selma, Aijaz H. Lone, Selma Amara   +11 more
core   +1 more source

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Dissection and Whole-Mount Immunofluorescent Staining of Mouse Hind Paw Muscles for Neuromuscular Junction Analysis

Bio-Protocol
The neuromuscular junction (NMJ) is a peripheral synaptic connection between a lower motor neuron and skeletal muscle fibre that enables muscle contraction in response to neuronal stimulation.
Rebecca Simkin, Elena Rhymes, Qiuhan Lang, Nicol Birsa, James Sleigh   +4 more
doaj   +1 more source

Statistical modelling of neuron degeneration [PDF]

, 2013
SUMMARY: Parkinson’s disease, Huntington’s disease, Amyotrophic lateral sclerosis (ALS) and Alzheimer’s disease are all examples of neurodegenerative disorders that result from the premature death of nerve cells or neurons.
Henderson, Robert, Pettitt, Tony, McCombe, Pam, Ridall, Gareth   +3 more
core  

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Impact of photon noise on the reliability of a motion-sensitive neuron in the fly's visual system [PDF]

, 2003
Grewe J, Kretzberg J, Warzecha A-K, Egelhaaf M. Impact of photon noise on the reliability of a motion-sensitive neuron in the fly's visual system. The journal of neuroscience.
Grewe, Jan, Egelhaaf, Martin ; https://orcid.org/, Warzecha, Anne-Kathrin, Kretzberg, Jutta   +3 more
core   +1 more source