Results 31 to 40 of about 2,225,985 (280)

Positive Spikes with Neuronal Migration Disorders

open access: yesPediatric Neurology Briefs, 1997
Five of fifteen children with histologically proven neuronal migration disorders (NMD) and refractory localization-related epilepsy had surface positive spikes or sharp waves or both on scalp EEG performed preoperatively in a study at The Hospital for ...
J Gordon Millichap
doaj   +2 more sources

Nucleokinesis in Neuronal Migration [PDF]

open access: yesNeuron, 2005
Neuronal migration is a critical phase of nervous system development and can be divided into two distinct phases: extension of the leading process and movement of the cell body and nucleus (nucleokinesis). Nucleokinesis appears to require many of the same cytoskeletal and signaling molecules used in cell mitosis.
Tsai, Li-Huei, Gleeson, Joseph G.
openaire   +2 more sources

Neuronal migration and ventral subtype identity in the telencephalon depend on SOX1 [PDF]

open access: yes, 2005
Little is known about the molecular mechanisms and intrinsic factors that are responsible for the emergence of neuronal subtype identity. Several transcription factors that are expressed mainly in precursors of the ventral telencephalon have been shown ...
Karagogeos, D.   +9 more
core   +4 more sources

Guiding Neuronal Cell Migrations [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2010
Neuronal migration is, along with axon guidance, one of the fundamental mechanisms underlying the wiring of the brain. As other organs, the nervous system has acquired the ability to grow both in size and complexity by using migration as a strategy to position cell types from different origins into specific coordinates, allowing for the generation of ...
Marín Parra, Óscar   +3 more
openaire   +3 more sources

Responsible Genes for Neuronal Migration in the Chromosome 17p13.3: Beyond Pafah1b1(Lis1), Crk and Ywhae(14-3-3ε)

open access: yesBrain Sciences, 2021
The 17p13.3 chromosome region is often deleted or duplicated in humans, resulting in severe neurodevelopmental disorders such as Miller–Dieker syndrome (MDS) and 17p13.3 duplication syndrome.
Xiaonan Liu   +3 more
doaj   +1 more source

Neuronal migration

open access: yesMechanisms of Development, 2001
Like other motile cells, neurons migrate in three schematic steps, namely leading edge extension, nuclear translocation or nucleokinesis, and retraction of the trailing process. In addition, neurons are ordered into architectonic patterns at the end of migration. Leading edge extension can proceed at the extremity of the axon, by growth cone formation,
Lambert De Rouvroit, Catherine   +1 more
openaire   +3 more sources

Loss of BAF Complex in Developing Cortex Perturbs Radial Neuronal Migration in a WNT Signaling-Dependent Manner

open access: yesFrontiers in Molecular Neuroscience, 2021
Radial neuronal migration is a key neurodevelopmental event indispensable for proper cortical laminar organization. Cortical neurons mainly use glial fiber guides, cell adhesion dynamics, and cytoskeletal remodeling, among other discrete processes, to ...
Godwin Sokpor   +17 more
doaj   +1 more source

Microtubules and motor proteins support zebrafish neuronal migration by directing cargo [PDF]

open access: yes, 2020
Neuronal migration during development is necessary to form an ordered and functional brain. Postmitotic neurons require microtubules and dynein to move, but the mechanisms by which they contribute to migration are not fully characterized. Using tegmental
Tobias P. Ring   +11 more
core   +2 more sources

Mutations in ARX result in several defects involving GABAergic neurons [PDF]

open access: yes, 2010
Genetic investigations of X-linked mental retardation have demonstrated the implication of ARX in a wide spectrum of disorders extending from phenotypes with severe neuronal migration defects, such as lissencephaly, to mild or moderate forms of mental ...
Friocourt, G.   +3 more
core   +1 more source

Neuronal Migration During Development of the Cerebellum

open access: yesFrontiers in Cellular Neuroscience, 2018
Neuronal migration is a fundamental process in central nervous system (CNS) development. The assembly of functioning neuronal circuits relies on neuronal migration occurring in the appropriate spatio-temporal pattern.
Maryam Rahimi-Balaei   +5 more
doaj   +1 more source

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