Results 241 to 250 of about 5,020,863 (306)

How is Nanoarchitectonics Shaping Extracellular Vesicle Research?

Advanced Healthcare Materials, EarlyView.
The convergence of nanoarchitectonics and extracellular vesicle biology is reshaping next‐generation nanomedicine by enabling rationally designed nanostructures for enhanced EVs detection, engineering, and therapy. ABSTRACT Extracellular vesicles (EVs) have gained recognition as crucial mediators of cell‐to‐cell communication, holding immense potential
Madushani Dahanayake, Md Shahriar A. Hossain, Chia‐Hung Liu, Carlos Salomon, Yusuke Yamauchi, Mostafa Kamal Masud   +5 more
wiley   +1 more source

Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development

Advanced Healthcare Materials, EarlyView.
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans, Abdulwahhab Khedr, Panagiotis G. Georgiou, Nehir Arik, Ozlem Sen, Steve P. Rannard, Tom O. McDonald, Christos Tapeinos   +7 more
wiley   +1 more source

A lightweight data-driven spiking neuronal network model of Drosophila olfactory nervous system with dedicated hardware support. [PDF]

Front Neurosci
Nanami T, Yamada D, Someya M, Hige T, Kazama H, Kohno T.   +5 more
europepmc   +1 more source

Photovoltaic Stimulation of Mouse and Pig Retina With Pyrolytic Carbon Microelectrodes Integrated on High‐Density Silicon Solar Cell Arrays

Advanced Healthcare Materials, EarlyView.
In this study, we fabricate photovoltaic retinal implants with pyrolytic carbon electrodes and test their ability to stimulate mouse and pig retinas when illuminated with near‐infrared light. We find increased spiking activity in both animal models compared to spontaneous activity and TTX controls and analyze the spike amplitude, latency and frequency.
Akihiro Matsumoto, Pratik Kusumanchi, Jesper Guldsmed Madsen, Asbjørn Cortnum Jørgensen, Gisele Alves dos Reis Benatto, Sune Thorsteinsson, Peter Behrensdorff Poulsen, Keisuke Yonehara, Toke Bek, Stephan Sylvest Keller, Rasmus Schmidt Davidsen   +10 more
wiley   +1 more source

Cholangioscopy-based convoluted neuronal network vs. confocal laser endomicroscopy in identification of neoplastic biliary strictures. [PDF]

Endosc Int Open
Robles-Medranda C, Baquerizo-Burgos J, Puga-Tejada M, Cunto D, Egas-Izquierdo M, Mendez JC, Arevalo-Mora M, Alcivar Vasquez J, Lukashok H, Tabacelia D.   +9 more
europepmc   +1 more source

The selfish network: how the brain preserves behavioral function through shifts in neuronal network state. [PDF]

Trends Neurosci
Stroh A, Schweiger S, Ramirez JM, Tüscher O.   +3 more
europepmc   +1 more source

Tau^P301L disengages from the proteosome core complex and neurogranin coincident with enhanced neuronal network excitability. [PDF]

Cell Death Dis
Hole KL, Zhu B, Huggon L, Brown JT, Mason JM, Williams RJ.   +5 more
europepmc   +1 more source

A Neuronal Network-Based Score Predicting Survival in Patients Undergoing Aortic Valve Intervention: The ABC-AS Score. [PDF]

J Clin Med
Barbieri F, Pfeifer BE, Senoner T, Dobner S, Spitaler P, Semsroth S, Lambert T, Zweiker D, Neururer SB, Scherr D, Schmidt A, Feuchtner GM, Hoppe UC, Adukauskaite A, Reinthaler M, Landmesser U, Müller S, Steinwender C, Dichtl W.   +18 more
europepmc   +1 more source

Astrocytes Regulate Neuronal Network Burst Frequency Through NMDA Receptors in a Species- and Donor-Specific Manner. [PDF]

Biol Psychiatry Glob Open Sci
Räsänen N, Tiihonen J, Koskuvi M, Lehtonen Š, Jalkanen N, Karmila N, Weert I, Vaurio O, Ojansuu I, Lähteenvuo M, Pietiläinen O, Koistinaho J.   +11 more
europepmc   +1 more source