Results 271 to 280 of about 211,725 (313)
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Neuronal plasticity and Parkinson disease
Molecular and Chemical Neuropathology, 1995The data reviewed here demonstrate a capacity for neuronal plasticity in the aged human brain, even when affected by neurodegenerative disorders. However, given their location and environment, these morphological changes may have beneficial or deleterious consequences.
P, Anglade +3 more
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Lipid Peroxides and Neuronal Plasticity
1999Long-term potentiation (LTP) of synaptic transmission is a well defined form of neuronal plasticity. The induction of LTP at perforant path-dentate granule cell and Schaffer collateral-CA1 pyramidal cell synapses of the hippocampus is known to require influx of Ca2+ through postsynaptic N-methy1-D-aspartate (NMDA) receptors, while the expression of LTP
M, Nishiyama +7 more
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Calcineurin regulation of neuronal plasticity
Biochemical and Biophysical Research Communications, 2003From the most basic of nervous systems to the intricate circuits found within the human brain, a fundamental requirement of neuronal function is that it be malleable, altering its output based upon experience. A host of cellular proteins are recruited for this purpose, which themselves are regulated by protein phosphorylation.
Rachel D, Groth +2 more
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Neuronal Modulation and Plasticity in Vitro
1994Publisher Summary This chapter emphasizes on the contribution that in vitro studies that have made in determining the influence of trophic factors and physical environment on neuronal survival and phenotypic plasticity. It also considers the control of neurite extension and growth cone activity in finding pathways and establishing synaptic ...
R A, Smith, Z G, Jiang
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Neuron–astrocyte communication and synaptic plasticity
Current Opinion in Neurobiology, 2010By forming close contacts with synapses, astrocytes secrete neuroactive substances and remove neurotransmitters, thus influencing the processing of information by the nervous system. Here, we review recent work on astrocytes and their roles in regulating neuronal function and synaptic plasticity.
Paixao, S., Klein, R.
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Postsynaptic actin and neuronal plasticity
Current Opinion in Neurobiology, 1999In the adult brain, actin is concentrated in dendritic spines where it can produce rapid changes in their shape. Through various synaptic junction proteins, this postsynaptic actin is linked to neurotransmitter receptors, influencing their function and, in turn, being influenced by them.
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Microglia in neuronal plasticity: Influence of stress
Neuropharmacology, 2015The central nervous system (CNS) has previously been regarded as an immune-privileged site with the absence of immune cell responses but this dogma was not entirely true. Microglia are the brain innate immune cells and recent findings indicate that they participate both in CNS disease and infection as well as facilitate normal CNS function.
Delpech, Jean-Christophe +5 more
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Diabetes and the plasticity of sensory neurons
Neuroscience Letters, 2015Diabetes mellitus targets sensory neurons during the development of peripheral neuropathy. While polyneuropathy is often routinely considered as another 'microvascular' complication of diabetes mellitus, this concept may no longer address the complexities and unique qualities of direct neuronal involvement. The list of altered molecules and pathways in
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Astrocyte–neuron interplay in maladaptive plasticity
Neuroscience & Biobehavioral Reviews, 2014The complexity of neuronal networks cannot only be explained by neuronal activity so neurobiological research in the last decade has focused on different components of the central nervous system: the glia. Glial cells are fundamental elements for development and maintenance of physiological brain work.
PAPA, Michele +4 more
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Establishment and plasticity of neuronal polarity
Journal of Neuroscience Research, 1999A fundamental feature of neurons is that they possess a polarized morphology, typified by a single long axon and several short dendrites. This cellular polarity forms the basis for directionalized rapid signaling, and for bi-directional trophic signaling, in neuronal circuits. While a catalog of structural, molecular, and functional differences between
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