Results 181 to 190 of about 127,268 (310)

The neuropharmacology of baclofen [PDF]

open access: yes, 1988
AI Shapovalov   +104 more
core   +1 more source

Intermediate filaments link glutamate–aspartate transporter deficiency to cochlear synaptopathy

open access: yesThe FEBS Journal, EarlyView.
In a healthy ear, GLAST transporters in supporting cells clear excess glutamate to protect auditory connections. When GLAST is missing, glutamate accumulates and leads to the destruction of structural scaffolding within the postsynaptic nerve endings. This internal collapse causes a loss of synapses that are essential for hearing, ultimately resulting ...
Paul Emmerich Krumpoeck   +1 more
wiley   +1 more source

Novel optimization of multi‐mechanistic approaches for the acute treatment of a migraine attack: A review

open access: yesHeadache: The Journal of Head and Face Pain, EarlyView.
Abstract Objective To highlight key factors required to optimize multi‐mechanistic approaches with oral combination treatments for the acute management of a migraine attack. Background Given the complex multi‐factorial nature of migraine, combining treatments with different mechanisms of action should improve outcomes compared to monotherapies, but ...
Stephen Silberstein, Alan M. Rapoport
wiley   +1 more source

Neuroimmune interactions in cardiovascular homeostasis and disease. [PDF]

open access: yesAm J Physiol Cell Physiol
Toumpourleka M, Stavrakis S.
europepmc   +1 more source

Exploring the microbiota–skin–brain axis: Chicory extract biotransformed into a postbiotic neurocosmetic enhancer of social and sensory experience

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Application of CHICORY EXTRACT by a consumer has the ability to evoke positive emotional responses in individuals who come into tactile contact with the treated skin. Abstract Objective Measuring the influence of cosmetic ingredients on the microbiota‐skin‐brain axis is a difficult challenge.
Stefan Hettwer   +4 more
wiley   +1 more source

Giants in the cold: Morphological evidence for vascular heat retention in the viscera but not the skeletal muscle of the basking shark (Cetorhinus maximus)

open access: yesJournal of Fish Biology, EarlyView.
Abstract Fewer than 50 of the over 30,000 extant species of fishes have developed anatomical specializations facilitating endothermy in specific body regions. The plankton‐feeding basking shark (Cetorhinus maximus), traditionally classified as an ectotherm, was recently shown to have regionally endothermic traits such as centralized red muscle (RM ...
C. Antonia Klöcker   +9 more
wiley   +1 more source

Control of feeding behavior by modified retrograde AAV to the gastrointestinal tract nerve afferents. [PDF]

open access: yesSci Rep
Marongiu R   +11 more
europepmc   +1 more source

Fish welfare in a changing world: New developments and current challenges

open access: yesJournal of Fish Biology, EarlyView.
Abstract The welfare of non‐human animals is central to ethical discussions on animal use, with increasing attention to fish welfare across research, aquaria, aquaculture, and fisheries. This paper reviews current theoretical approaches to animal welfare and recent advances in defining and assessing fish welfare since the seminal paper by Huntingford ...
Sonia Rey Planellas   +16 more
wiley   +1 more source

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