Results 121 to 130 of about 2,639,581 (370)
Iron and glutathione at the crossroad of redox metabolism in neurons
Neurons, as non-dividing cells, encounter a myriad of stressful conditions throughout their lifespan. In particular, there is increasing evidence that iron progressively accumulates in the brain with age and that iron-induced oxidative stress is the ...
PAULA ARACENA +3 more
doaj
The Condition of the Vasomotor Neurons in Shock [PDF]
W. T. Porter, William C. Quinby
openalex +1 more source
The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel +8 more
wiley +1 more source
CIRCADIAN GATING OF GLUCOCORTICOID RECEPTOR IN BRAIN CELLS
Katharina Haury +2 more
doaj +1 more source
Emerging Roles of Long Non-Coding RNAs as Drivers of Brain Evolution
Mammalian genomes encode tens of thousands of long-noncoding RNAs (lncRNAs), which are capable of interactions with DNA, RNA and protein molecules, thereby enabling a variety of transcriptional and post-transcriptional regulatory activities.
Geraldine Zimmer-Bensch
doaj +1 more source
Microtubules: The neuronic system of the neurons?
20 pages LATEX, no figures; Invited talk by D.V.N.
Mavromatos, N. E., Nanopoulos, D. V.
openaire +2 more sources
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti +8 more
wiley +1 more source
Excitation Dropout: Encouraging Plasticity in Deep Neural Networks
We propose a guided dropout regularizer for deep networks based on the evidence of a network prediction defined as the firing of neurons in specific paths.
Bargal, Sarah Adel +5 more
core
CA1-projecting subiculum neurons facilitate object-place learning. [PDF]
Recent anatomical evidence suggests a functionally significant back-projection pathway from the subiculum to the CA1. Here we show that the afferent circuitry of CA1-projecting subicular neurons is biased by inputs from CA1 inhibitory neurons and the ...
Chen, Lujia +12 more
core +1 more source

