Results 121 to 130 of about 2,639,581 (370)

Iron and glutathione at the crossroad of redox metabolism in neurons

open access: yesBiological Research, 2006
Neurons, as non-dividing cells, encounter a myriad of stressful conditions throughout their lifespan. In particular, there is increasing evidence that iron progressively accumulates in the brain with age and that iron-induced oxidative stress is the ...
PAULA ARACENA   +3 more
doaj  

The Condition of the Vasomotor Neurons in Shock [PDF]

open access: green, 1903
W. T. Porter, William C. Quinby
openalex   +1 more source

The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells

open access: yesFEBS Open Bio, EarlyView.
We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel   +8 more
wiley   +1 more source

CIRCADIAN GATING OF GLUCOCORTICOID RECEPTOR IN BRAIN CELLS

open access: yesIBRO Neuroscience Reports, 2023
Katharina Haury   +2 more
doaj   +1 more source

Emerging Roles of Long Non-Coding RNAs as Drivers of Brain Evolution

open access: yesCells, 2019
Mammalian genomes encode tens of thousands of long-noncoding RNAs (lncRNAs), which are capable of interactions with DNA, RNA and protein molecules, thereby enabling a variety of transcriptional and post-transcriptional regulatory activities.
Geraldine Zimmer-Bensch
doaj   +1 more source

Microtubules: The neuronic system of the neurons?

open access: yes, 1997
20 pages LATEX, no figures; Invited talk by D.V.N.
Mavromatos, N. E., Nanopoulos, D. V.
openaire   +2 more sources

Short‐term actions of epigalocatechin‐3‐gallate in the liver: a mechanistic insight into hypoglycemic and potential toxic effects

open access: yesFEBS Open Bio, EarlyView.
Epigallocatechin‐3‐gallate (EGCG) acutely inhibited gluconeogenesis and enhanced glycolysis, glycogenolysis, and fatty acid oxidation in perfused rat livers. Mechanistic assays revealed mitochondrial uncoupling, inhibition of pyruvate carboxylation and glucose‐6‐phosphatase, shift of NADH/NAD+ ratios toward oxidation, and loss of membrane integrity ...
Carla Indianara Bonetti   +8 more
wiley   +1 more source

Excitation Dropout: Encouraging Plasticity in Deep Neural Networks

open access: yes, 2019
We propose a guided dropout regularizer for deep networks based on the evidence of a network prediction defined as the firing of neurons in specific paths.
Bargal, Sarah Adel   +5 more
core  

CA1-projecting subiculum neurons facilitate object-place learning. [PDF]

open access: yes, 2019
Recent anatomical evidence suggests a functionally significant back-projection pathway from the subiculum to the CA1. Here we show that the afferent circuitry of CA1-projecting subicular neurons is biased by inputs from CA1 inhibitory neurons and the ...
Chen, Lujia   +12 more
core   +1 more source

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