Results 141 to 150 of about 2,597,556 (387)

A Novel CHMP2B Splicing Variant in Atypical Presentation of Familial Frontotemporal Lobar Degeneration

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT C‐truncating variants in the charged multivesicular body protein 2B (CHMP2B) gene are a rare cause of frontotemporal lobar degeneration (FTLD), previously identified only in Denmark, Belgium, and China. We report a novel CHMP2B splice‐site variant (c.35‐1G>A) associated with familial FTLD in Spain. The cases were two monozygotic male twins who
Sara Rubio‐Guerra   +17 more
wiley   +1 more source

Microglial identity and inflammatory responses are controlled by the combined effects of neurons and astrocytes

open access: yesCell Reports, 2021
Summary: Microglia, brain-resident macrophages, require instruction from the CNS microenvironment to maintain their identity and morphology and regulate inflammatory responses, although what mediates this is unclear.
Paul S. Baxter   +6 more
doaj  

The Condition of the Vasomotor Neurons in Shock [PDF]

open access: green, 1903
W. T. Porter, William C. Quinby
openalex   +1 more source

Super Neurons

open access: yesIEEE Transactions on Emerging Topics in Computational Intelligence
Self-Organized Operational Neural Networks (Self-ONNs) have recently been proposed as new-generation neural network models with nonlinear learning units, i.e., the generative neurons that yield an elegant level of diversity; however, like its predecessor, conventional Convolutional Neural Networks (CNNs), they still have a common drawback: localized ...
Serkan Kiranyaz   +7 more
openaire   +4 more sources

Microtubules: The neuronic system of the neurons?

open access: yes, 1997
20 pages LATEX, no figures; Invited talk by D.V.N.
Mavromatos, N. E., Nanopoulos, D. V.
openaire   +2 more sources

KIF5A p.Pro986Leu Risk Variant and Accelerated Progression of Amyotrophic Lateral Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study explored the impact of KIF5A rs113247976 (p.Pro986Leu), a risk allele for amyotrophic lateral sclerosis (ALS), on phenotypic variability in two Italian ALS cohorts (discovery, n = 865; replication, n = 1174). The minor allele (T) frequency was 0.015.
Arianna Manini   +24 more
wiley   +1 more source

CNS Mitochondria‐Derived Vesicle in Blood: Potential Biomarkers for Brain Mitochondria Dysfunction

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial dysfunction is a hallmark of neurodegenerative diseases like Alzheimer's (AD) and Parkinson's (PD). Our goal was to develop practical, noninvasive methods to assess mitochondrial status through the detection of mitochondria‐derived vesicles (MDVs).
Qi Liu   +12 more
wiley   +1 more source

Signal transduction and gene expression regulated by calcium release from internal stores in excitable cells

open access: yesBiological Research, 2004
Calcium regulation of several transcription factors involves different calcium-dependent signaling cascades and engages cytoplasmic as well as nuclear calcium signals.
MARÍA ANGÉLICA CARRASCO   +3 more
doaj  

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