Results 151 to 160 of about 141,892 (193)
Some of the next articles are maybe not open access.
Nature Reviews Neurology, 2014
Pruritus, also known as itch, is a very common, unpleasant sensation that elicits an urge to scratch. Its origin is not always in the skin, and neuropathic itch that is caused by neuronal or glial damage is common, but poorly understood by both dermatologists and neurologists.
Laurent Misery +2 more
exaly +3 more sources
Pruritus, also known as itch, is a very common, unpleasant sensation that elicits an urge to scratch. Its origin is not always in the skin, and neuropathic itch that is caused by neuronal or glial damage is common, but poorly understood by both dermatologists and neurologists.
Laurent Misery +2 more
exaly +3 more sources
Pain, 2019
Abstract Neuropathic itch is clinically important but has received much less attention as compared to neuropathic pain. In the past decade, itch-specific pathways have been characterized on a cellular and molecular level, but their exact role in the pathophysiology of neuropathic itch is still unclear.
Steinhoff M. +4 more
openaire +3 more sources
Abstract Neuropathic itch is clinically important but has received much less attention as compared to neuropathic pain. In the past decade, itch-specific pathways have been characterized on a cellular and molecular level, but their exact role in the pathophysiology of neuropathic itch is still unclear.
Steinhoff M. +4 more
openaire +3 more sources
The Lancet, 1974
Abstract Some patients with cauda equina lesions have urethral obstruction at the membranous level despite flaccidity of the pelvic-floor muscles. Our experience with two recent cases suggests that this problem may not be a mechanical one, as hitherto assumed, but due to contraction of the smooth muscle of the urethra which is activated by the ...
B J, Abel +3 more
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Abstract Some patients with cauda equina lesions have urethral obstruction at the membranous level despite flaccidity of the pelvic-floor muscles. Our experience with two recent cases suggests that this problem may not be a mechanical one, as hitherto assumed, but due to contraction of the smooth muscle of the urethra which is activated by the ...
B J, Abel +3 more
openaire +2 more sources
Hospital Medicine, 2000
Neuropathic pain is a distressing, poorly understood and under-treated condition. In this review we seek to examine the definition and classification of neuropathic pain, summarize clinically important underlying mechanisms, outline current management strategies and look at future directions for research and therapy.
T E, Smith, M S, Chong
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Neuropathic pain is a distressing, poorly understood and under-treated condition. In this review we seek to examine the definition and classification of neuropathic pain, summarize clinically important underlying mechanisms, outline current management strategies and look at future directions for research and therapy.
T E, Smith, M S, Chong
openaire +2 more sources
Current Opinion in Neurology, 2001
Damage to peripheral nerves triggers a cascade of events in axotomized sensory neurones that are generally believed to be responsible for the generation of neuropathic pain. Recent data in animal models show that alterations in the properties of undamaged neurones that project into a damaged nerve can also play an important role.
M, Koltzenburg, J, Scadding
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Damage to peripheral nerves triggers a cascade of events in axotomized sensory neurones that are generally believed to be responsible for the generation of neuropathic pain. Recent data in animal models show that alterations in the properties of undamaged neurones that project into a damaged nerve can also play an important role.
M, Koltzenburg, J, Scadding
openaire +2 more sources
2013
Neuropathic pain is a clinical entity that presents unique diagnostic and therapeutic challenges. This chapter addresses the classification, epidemiology, pathophysiology, diagnosis, and treatment of neuropathic pain syndrome. Neuropathic pain can be distinguished from nociceptive pain based on clinical signs and symptoms.
Eric, Kerstman +4 more
openaire +2 more sources
Neuropathic pain is a clinical entity that presents unique diagnostic and therapeutic challenges. This chapter addresses the classification, epidemiology, pathophysiology, diagnosis, and treatment of neuropathic pain syndrome. Neuropathic pain can be distinguished from nociceptive pain based on clinical signs and symptoms.
Eric, Kerstman +4 more
openaire +2 more sources
Understanding Neuropathic Pain
CNS Spectrums, 2005AbstractNeuropathic pain is defined as a chronic pain condition that occurs or persists after a primary lesion or dysfunction of the peripheral or central nervous system. Traumatic injury of peripheral nerves also increases the excitability of nociceptors in and around nerve trunks and involves components released from nerve terminals (neurogenic ...
Zieglgänsberger, W. +2 more
openaire +3 more sources
Outflow Obstruction in Neuropathic Bladder Dysfunction: The Neuropathic Urethra
British Journal of Urology, 1978Summary— Urethral pressure profiles were recorded in a series of patients with traumatic lesions of the spinal cord producing vesico‐urethral dysfunction. Patients were classified into groups depending upon the relationship of the lesion to the sympathetic outflow to the bladder and urethra from the spinal cord.
G S, Sunder, K F, Parsons, N O, Gibbon
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Food and Chemical Toxicology, 2015
The present study explores the role of simvastatin in vincristine-induced neuropathic pain, which was induced by administering vincristine (100 µg/kg i.p.) for 10 days (two 5 day cycles with 2 days pause). Pain was assessed by determining mechanical hyperalgesia, mechanical dynamic allodynia, heat hyperalgesia and cold allodynia.
Shrutya, Bhalla +2 more
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The present study explores the role of simvastatin in vincristine-induced neuropathic pain, which was induced by administering vincristine (100 µg/kg i.p.) for 10 days (two 5 day cycles with 2 days pause). Pain was assessed by determining mechanical hyperalgesia, mechanical dynamic allodynia, heat hyperalgesia and cold allodynia.
Shrutya, Bhalla +2 more
openaire +2 more sources
Epidemiology of Neuropathic Pain
Pain Management, 2010Epidemiology is an essential clinical tool in designing and evaluating management and prevention strategies, and is particularly relevant to neuropathic pain. Despite its relevance to neuropathic pain however, there is a paucity of accurate information on its prevalence, distribution and determinants, for several reasons.
Blair H, Smith, Nicola, Torrance
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