Results 351 to 360 of about 1,846,055 (403)
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Brain Research, 1999
Although chronic neuropathic pain disorders are more prevalent in the senescent population, little is known about how the aging process alters the thermal hyperalgesic sensitivity to peripheral nerve injury. In this study, neuropathic pain was induced in young, mature and aged FBNF1 hybrid rats via unilateral ligation of the left sciatic nerve.
J C, Novak +5 more
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Although chronic neuropathic pain disorders are more prevalent in the senescent population, little is known about how the aging process alters the thermal hyperalgesic sensitivity to peripheral nerve injury. In this study, neuropathic pain was induced in young, mature and aged FBNF1 hybrid rats via unilateral ligation of the left sciatic nerve.
J C, Novak +5 more
openaire +2 more sources
Current Treatment Options in Neurology, 2015
Neuropathic pain is notoriously variable in its severity and impact on patients, as well as in its response to treatment. Certain therapies for neuropathic pain have better evidence for their use; however, it is apparent that although some therapies provide relief for only a minority of patients, the relief may be significant.
Matthew T, Mendlik, Tanya J, Uritsky
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Neuropathic pain is notoriously variable in its severity and impact on patients, as well as in its response to treatment. Certain therapies for neuropathic pain have better evidence for their use; however, it is apparent that although some therapies provide relief for only a minority of patients, the relief may be significant.
Matthew T, Mendlik, Tanya J, Uritsky
openaire +2 more sources
Microglia and neuropathic pain
Glia, 2009AbstractIn contrast to physiological pain, pathological pain is not dependent on the presence of tissue‐damaging stimuli. One type of pathological pain—neuropathic pain—is often a consequence of nerve injury or of diseases such as diabetes, AIDS, or cancer.
Kazuhide, Inoue, Makoto, Tsuda
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Medical Clinics of North America, 2016
Neuropathic pain (NP) arises from injuries or diseases affecting the somatosensory component of the nervous system at any level of the peripheral or central nervous system. NP is diagnosed based on common neurologic signs and symptoms. NP is best treated with a combination of multiple therapeutic approaches, and treatments include conservative ...
Robert Carter Wellford, Jones +2 more
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Neuropathic pain (NP) arises from injuries or diseases affecting the somatosensory component of the nervous system at any level of the peripheral or central nervous system. NP is diagnosed based on common neurologic signs and symptoms. NP is best treated with a combination of multiple therapeutic approaches, and treatments include conservative ...
Robert Carter Wellford, Jones +2 more
openaire +2 more sources
The management of neuropathic pain
Neurosurgery Clinics of North America, 2004Although the definitive treatment for neuropathic pain remains elusive, scientific investigation continues to provide the field with better and better therapies. As our understanding of the neurophysiologic mechanisms of pain improves, pharmaceutic therapies have become more effective even as side effects are minimized.
Jacob, Schwarz, Neal, Naff
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Role of the immune system in neuropathic pain
Scandinavian Journal of Pain, 2019Background Acute pain is a warning mechanism that exists to prevent tissue damage, however pain can outlast its protective purpose and persist beyond injury, becoming chronic.
M. Malcangio
semanticscholar +1 more source
Venlafaxine and Neuropathic Pain
Pharmacology, 2013The possible mechanisms involved in the antinociceptive effect of venlafaxine (VFX), a selective serotonin and noradrenaline reuptake inhibitor, after a single administration and chronic treatment were investigated in a diabetic neuropathic pain (DNP) model.
Krystyna, Cegielska-Perun +4 more
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Pain-resolving immune mechanisms in neuropathic pain
Nature Reviews Neurology, 2023Nathan T. Fiore +4 more
semanticscholar +1 more source
Current Pain and Headache Reports, 2005
Whether opioids are effective for neuropathic pain has been a matter of controversy for decades. Within limits, it is clear that opioids in general are effective for neuropathic pain. Furthermore, there is no evidence that opioids are any less effective for neuropathic pain than for non-neuropathic pain, no evidence that opioids are less effective for ...
Nathaniel, Katz, Christine, Benoit
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Whether opioids are effective for neuropathic pain has been a matter of controversy for decades. Within limits, it is clear that opioids in general are effective for neuropathic pain. Furthermore, there is no evidence that opioids are any less effective for neuropathic pain than for non-neuropathic pain, no evidence that opioids are less effective for ...
Nathaniel, Katz, Christine, Benoit
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Pathophysiology of neuropathic pain
Pain Management Nursing, 2004Neuropathic pain is caused by damage to the nervous system. Unlike physiologic pain (also known as nociceptive pain), neuropathic pain is not self-limited and is not as easily treated. The etiologic causes of neuropathic pain are many and varied in their scope.
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