Results 171 to 180 of about 97,051 (285)

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

open access: yesBritish Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli   +7 more
wiley   +1 more source

AD-related plasma biomarkers in centenarians: links to cognition and neuropathology. [PDF]

open access: yesAlzheimers Dement
Lorenz LMC   +13 more
europepmc   +1 more source

Epidemiology of progressive intellectual and neurological deterioration in UK children

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
This study of PIND in UK children was carried out via the British Paediatric Surveillance Unit from 1997 to 2024. It identified six cases of vCJD. 2367 children had other diagnoses explain their deterioration. There were 259 other diseases in the diagnosed group.
Christopher M. Verity   +3 more
wiley   +1 more source

Beyond diabetes and obesity: GLP‐1 receptor agonists in disrupting the vicious cycle of metabolic dysfunction and neuroinflammation

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Neurodegenerative diseases, including debilitating conditions like Alzheimer's and Parkinson's, are characterized by progressive neuronal loss, a process fundamentally driven by persistent chronic neuroinflammation and central metabolic dysfunction.
Renata Spezani   +1 more
wiley   +1 more source

Dysregulated calcium signaling in the aged primate association cortices: vulnerability to Alzheimer’s disease neuropathology [PDF]

open access: gold
Amy F.T. Arnsten   +6 more
openalex   +1 more source

Early detection of type 2 diabetes mellitus‐associated cognitive dysfunction: The potential of amide proton transfer‐weighted imaging

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Type 2 diabetes mellitus (T2DM) may lead to diabetes‐associated cognitive dysfunction (DACD). We aimed to develop an amide proton transfer‐weighted (APTw) magnetic resonance imaging (MRI) biomarker to assist early identification of T2DM with DACD. Materials and Methods The study included 27 T2DM patients, comprising 19 with mild cognitive
Ju‐wei Shao   +5 more
wiley   +1 more source

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