Results 191 to 200 of about 115,701 (249)

Changes in Nighttime Sleep Duration and Their Association With Cognitive Decline and Dementia Risk

Journal of Sleep Research, EarlyView.
ABSTRACT This study investigates changes in nighttime sleep duration in relation to cognitive decline and risk of incident dementia. A total of 3057 participants from the Swedish population study ‘Good Aging in Skåne’ (Mage = 68.4) with normal baseline sleep duration (6–8 h) were followed up to 20 years (Myears = 8.39). Self‐reported change was defined
Marieclaire Overton, Sölve Elmståhl, Rani Basna   +2 more
wiley   +1 more source

Purpose in life and blood-based biomarkers of brain health. [PDF]

J Gerontol B Psychol Sci Soc Sci
Sutin AR, Luchetti M, Stephan Y, Terracciano A.   +3 more
europepmc   +1 more source

Neurite Imaging Reveals Widespread Alterations in Grey Matter Neurite Morphology in Obstructive Sleep Apnoea

Journal of Sleep Research, EarlyView.
ABSTRACT Obstructive sleep apnoea (OSA) is a common chronic multisystem disorder, and cortical structural alterations have been detected via conventional neuroimaging techniques. Recent advances in diffusion‐weighted imaging have yielded novel techniques for investigating neural microstructure, which may potentially offer supplementary insights into ...
Liping Qi, Qiu Chu, Ya‐Jie Liu, Rong‐Hua Li, Ling Wen, Yong‐Zhong Lin   +5 more
wiley   +1 more source

Publisher Correction: Activity-dependent ribosome profiling reveals the landscape of canonical and non-canonical translation in brain tissue. [PDF]

Nat Commun
Suryawanshi N, Uchida H, Endo R, Sato K, Satoh D, Tsumagari K, Imami K, Mikuni T, Tanaka M.   +8 more
europepmc   +1 more source

From senescence and inflammaging to systemic comorbidities: Drivers of aging‐associated periodontitis

Periodontology 2000, EarlyView.
Abstract Background Aging is accompanied by a chronic low‐grade inflammatory process, known as inflammaging, as well as immunosenescence, an age‐related decline and dysregulation of immune function, and cellular senescence, a process in which cells enter a state of irreversible growth arrest while actively releasing pro‐inflammatory factors.
James Cheng, Chew Tin Zar Aung, Samuel F. Suslavich, Sinem Esra Sahingur, Yvonne L. Hernandez‐Kapila   +4 more
wiley   +1 more source

Retraction Note: Neuroinflammation is associated with infiltration of T cells in Lewy body disease and α-synuclein transgenic models. [PDF]

J Neuroinflammation
Iba M, Kim C, Sallin M, Kwon S, Verma A, Overk C, Rissman RA, Sen R, Sen JM, Masliah E.   +9 more
europepmc   +1 more source

Understanding extracellular vesicles in antiaging

Periodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad, Nathan E. Estrin, Anton Sculean, Richard J. Miron   +3 more
wiley   +1 more source

Associations of Alzheimer Disease and Related Dementia Neuropathologies With Timely Diagnosis of Dementia in Healthcare Settings. [PDF]

Neurology
Chen Y, Chen A, Power MC, Grodstein F, Kapasi A, Capuano AW, Lange-Maia BS, Moghtaderi A, Stapp EK, Bhattacharyya J, Shah RC, Barnes LL, Bennett DA, James BD.   +13 more
europepmc   +1 more source

From mouth to brain: Linking periodontal and peri‐implant dysbiosis to systemic inflammation and neuropathology

Periodontology 2000, EarlyView.
Abstract Background/Aim Growing evidence suggests that imbalances occurring within the human microbiota and deregulation of the host immune response may play a significant role in the development of neurodegenerative diseases. Materials and Methods A comprehensive narrative review of the latest experimental, clinical, and epidemiological insights was ...
Emilio A. Cafferata, Frank Schwarz, Jaime Díaz‐Zúñiga, Alpdogan Kantarci   +3 more
wiley   +1 more source