Results 171 to 180 of about 115,701 (249)

TRPM3 regulates fear memory encoding and seizure susceptibility in the lateral amygdala

British Journal of Pharmacology, EarlyView.
Abstract Background and purpose TRPM3 is best known for its role as a peripheral sensor of pain and heat. Recent studies reporting gain‐of‐function TRPM3 mutations in patients with neurodevelopmental and epilepsy‐associated disorders suggest a previously unrecognized role of this channel in the brain.
Attila Gyéresi, Laura Mundrucz, Máté Deák, Angéla Kecskés, Éva Borbély, Viktória Kormos, Balázs Gaszner, Orsolya Mihály, Balázs István Tóth, Joris Vriens, Thomas Voets, Erzsébet Kövesdi, Miklós Kecskés   +12 more
wiley   +1 more source

Oxidative Stress Drives Cell Cycle Stalling, Apoptosis and Metabolic Suppression in Cystatin B Deficient EPM1 Patient iPSCs

Cell Proliferation, EarlyView.
CSTB deficient EPM1 iPS cells manifest increased lysosomal activity and oxidative stress, which lead to DNA damage, cell cycle defects and increased apoptosis. As a protective response, metabolism is suppressed. Image created by BioRender https://BioRender.com/t44oc6h.
Shekhar Singh, Lidiia Plotnikova, Teemu Tiukuvaara, Reetta Kälviäinen, Riikka H. Hämäläinen   +4 more
wiley   +1 more source

A most important gift: the critical role of postmortem brain tissue in autism science

Frontiers in Neurology
Marvin R. Natowicz, Marvin R. Natowicz, Margaret L. Bauman, Stephen M. Edelson   +3 more
doaj   +1 more source

Probing effect modification by socioeconomic status in associations between blood biomarkers of neuropathology and cognitive outcomes in the United States and India. [PDF]

Alzheimers Dement
Nichols E, Kim JK, Aksman LM, Gross AL, Hu P, Kobayashi LC, Thyagarajan B, Lee J, Crimmins EM.   +8 more
europepmc   +1 more source

Aberrant Expression of Multiple T‐Cell Markers in Primary Cutaneous Follicle Center Lymphoma: A Rare Case Report

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Aberrant expression of T‐cell markers in B‐cell lymphomas is rare and can pose diagnostic challenges. We report a case of a 65‐year‐old man presenting with newly developed scalp nodules. Histopathology revealed nodular lymphoid infiltrates composed of large centrocytes and centroblasts.
V. Pfefferle, A. Vogelsberg, M. Maaß, C. M. Schürch, S. Forchhammer   +4 more
wiley   +1 more source

Immune-Enriched Versus Matrix-Remodeling Microenvironments in Psammoma Body-Rich and Psammoma Body-Poor WHO Grade I Meningiomas: An Exploratory Transcriptomic Study. [PDF]

Neuropathology
Fatima T.
europepmc   +1 more source

Minor neurological dysfunction in children with developmental coordination disorder

Developmental Medicine &Child Neurology, EarlyView.
Aim To provide insight into the prevalence and types of minor neurological dysfunction (MND) in subtypes of children with developmental coordination disorder (DCD) and in relation to behavioural‐emotional problems. Method A retrospective medical record study was conducted.
Marina M. Schoemaker, Jessica M. Lust, Anke Verhaegh, Ankie Diepstraten, Peter H. Wilson, Mijna Hadders‐Algra, Bert Steenbergen   +6 more
wiley   +1 more source

Forensic neuropathology: 2026 update. [PDF]

Free Neuropathol
Matschke J.
europepmc   +1 more source

AOSNP-ADAPTR resource level-based recommendations on practical diagnostic strategies for ependymomas. [PDF]

Brain Pathol
Adapting Diagnostic Approaches for Practical Taxonomy in Resource‐Restrained Regions (ADAPTR) recommendations for ependymomas in resource‐restrained settings (RL = resource level; created in BioRender). Abstract Ependymomas are uncommon primary tumors of the central nervous system (CNS) that affect both children and adults.
Satgunaseelan L, Buckland ME, Chacko G, Masui K, Shibahara J, Santosh V, Al-Hussaini M, Park SH, Tihan T, Ng HK, Wesseling P, Louis DN, Sarkar C, Komori T.   +13 more
europepmc   +2 more sources

Enhancement of the leptomeninges in a young man

Brain Pathology, EarlyView.
Jayden Ray, Mohammad Alberawi, Andrew Bauer, Kar‐Ming Fung, Erika Santos Horta, Lorraina J. Robinson   +5 more
wiley   +1 more source