Results 231 to 240 of about 97,051 (285)
CDC42‐Effector Proteins Regulate Higher Order Structure of Septins Required for CNS Myelin Integrity
Glia, Volume 74, Issue 3, March 2026.CDC42‐effector proteins 1/2 are present in CNS myelin. They facilitate the higher order structure of myelin septin filaments. Their loss impairs septin‐dependent scaffolding of myelin. Myelin outfoldings do not cause secondary neuropathology per se. ABSTRACT The regular structure of CNS myelin requires specialized structural proteins, including septin ...
Sophie Hümmert +14 more
wiley +1 more source
Brain Pathology, Volume 36, Issue 2, March 2026.Post mortem MRI was combined with neuropathological assessments at 600 μm intervals throughout the brain. Through this approach, a three dimensional account of an entire human brain with an intermediate Alzheimer's disease neuropathologic change was created.
Anneke Alkemade +13 more
wiley +1 more source
Sialylation patterns in cerebral amyloid angiopathy
Brain Pathology, Volume 36, Issue 2, March 2026.This study is the first to localize and evaluate sialylation modifications in the context of Alzheimer's Disease and Cerebral Amyloid Angiopathy, revealing a unique disease‐specific increase in intravascular sialylation. Abstract Glycosylation is the most common form of post‐translational modification in the brain and becomes significantly altered in ...
Caitlyn Fastenau +8 more
wiley +1 more source
Brain Pathology, Volume 36, Issue 2, March 2026.Deep learning tissue mapping can guide region of interest selection for spatial transcriptomic analyses. Using this method, a transcriptional catalogue of focal cortical dysplasia type IIb was generated, revealing enrichment for markers of inhibitory glycinergic signaling in cytomegalic dysmorphic neurons.
Ameesha Paliwal +8 more
wiley +1 more source
Analyses of the Effects of Wild-Type TDP-43 Overexpression in Oxytocin Neurons in Mice. [PDF]
Neuropathol Appl NeurobiolBergh S, Simonsson O, Petersén Å.
europepmc +1 more source