Results 21 to 30 of about 97,051 (285)
Amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) lie at opposing ends of a clinical, genetic, and neuropathological continuum.
David Reyes-Leiva +27 more
doaj +1 more source
Microglia are dependent on signaling through the colony stimulating factor-1 receptor (CSF-1R/CD115) for growth and survival. Activation of CSF-1R can lead to cell division, while blocking CSF-1R can lead to rapid microglia cell death.
Douglas G. Walker +4 more
doaj +1 more source
Greenfield's Neuropathology [PDF]
Greenfield's Neuropathology Editors: S. Love, D. N. Louis, D. W. Ellison Hodder Arnold, London, UK Copyright © 2008 2244 pages, $475. The editors' preface to the 2 volumes of the eighth edition of Greenfield's succinctly outlines the text's role and purpose in the neuropathology cosmos: "Our aim has been to ensure that Greenfield's Neuropathology ...
openaire +2 more sources
Inflammation is considered a key pathological process in neurodegenerative diseases, including Alzheimer’s disease (AD) and Parkinson’s disease (PD), but there are still mechanisms not understood.
Douglas G. Walker +3 more
doaj +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Cerebral spinal fluid - cytology tumours - applications of light microscopic methods tumours - applications of ultrastructural methods tumours - applications of immunocytochemical methods tumours of the pituitary region vascular diseases bacterial, fungal, protozoal and parasitic infections viral infections AIDS and the central nervous system ...
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ABSTRACT Introduction Neuronal pentraxin 2 (NPTX2) is a synaptic protein involved in synaptic plasticity and regulation of neuronal excitability. Lower baseline cerebrospinal fluid (CSF) NPTX2 levels have been shown to be associated with an earlier onset of mild cognitive impairment (MCI), a pre‐dementia syndrome, even after CSF Alzheimer's Disease (AD)
Juan P. Vazquez +12 more
wiley +1 more source

