Results 91 to 100 of about 448,569 (309)

Rheumatologic Manifestations of Patients With Type B Insulin Resistance

Arthritis Care &Research, EarlyView.
Objective The objectives of this study were to identify laboratory and clinical features associated with type B insulin resistance (TBIR), a rare condition caused by autoantibodies that inhibit the insulin receptor, most frequently occurring in the setting of systemic lupus erythematosus (SLE), and to increase awareness of this rare, life‐threatening ...
S. Amara Ogbonnaya, Sandra G. Williams, Raphael A. Kirou, Marissa Lightbourne, Rebecca J. Brown   +4 more
wiley   +1 more source

A Narrative Review of the Dorsal Root Ganglia and Spinal Cord Mechanisms of Action of Neuromodulation Therapies in Neuropathic Pain

Brain Sciences
Neuropathic pain arises from injuries to the nervous system in diseases such as diabetes, infections, toxicity, and traumas. The underlying mechanism of neuropathic pain involves peripheral and central pathological modifications.
Matheus Deroco Veloso da Silva, Geovana Martelossi-Cebinelli, Kelly Megumi Yaekashi, Thacyana T. Carvalho, Sergio M. Borghi, Rubia Casagrande, Waldiceu A. Verri   +6 more
doaj   +1 more source

High Plasma Tnf-? Levels And Mononuclear Cells Inos And Tnf-? Expression AS Risk Factors For Painful Diabetic Neuropathy [PDF]

, 2010
Painful Diabetic Neuropathy (PDN) is one of the most common and annoyingcomplications of diabetes mellitus. The pathogenesis of PDN is complex and still unclear.Recently it has become clear that nitric oxide (NO) and proinflammatory cytokines playan ...
Purwata, T. E. (Thomas), Raka Sudewi, A. A, Suastika, K. (Ketut), Widjaja, D. (Djoenaidi)   +3 more
core  

OPA1-related auditory neuropathy: site of lesion and outcome of cochlear implantation. [PDF]

, 2015
Hearing impairment is the second most prevalent clinical feature after optic atrophy in Dominant Optic Atrophy associated with mutations in the OPA1 gene.
Arslan, E, Biscaro, A, Cama, Elona, Caporali, L, Carelli, V., La Morgia, C, Liguori, R, Magnavita, V, Monteleone, A, Rossi, R, Santarelli, Rosamaria, Scimemi, Pietro, Valentino, Ml   +12 more
core   +3 more sources

Neuropathy [PDF]

Canadian Journal of Diabetes, 2013
Vera, Bril, Bruce, Perkins, Cory, Toth
openaire   +2 more sources

Cracking the Code: Which Ocular Symptoms Predict Dry Eye Signs? Insights from a large international sicca registry

Arthritis Care &Research, Accepted Article.
Purpose The study aimed to identify symptom‐based predictors of dry eye disease (DED) signs in the Sjögrens International Collaborative Clinical Alliance (SICCA) cohort. Methods Retrospective analysis examining 16 ocular symptoms (most graded 0‐4) and artificial tear (AT) use (graded 0‐3) as predictors of DED signs [abnormal ocular surface staining ...
Pragnya R Donthineni, Chloe Shields, Rohit Muralidhar, Shreya Bhatt, Alan Baer, Robert Fox, Sara S. McCoy, Anat Galor   +7 more
wiley   +1 more source

Ageing Signatures and Disturbed Muscle Regeneration in Muscle Proteome of Inclusion Body Myositis

Journal of Cachexia, Sarcopenia and Muscle
Background Inclusion body myositis (IBM) is the most common acquired myopathy in adults over the age of 50 years, characterised by inflammatory and degenerative features that lead to progressive muscle weakness and physical disability for lack of ...
Geert M. deVries, Bob Asselbergh, Alice Monticelli, Peter De Jonghe, Stuart Maudsley, Peter Y. K. Van Den Bergh, Anne Bigot, Jan L. De Bleecker, Biljana Ermanoska, Willem De Ridder, Jonathan Baets   +10 more
doaj   +1 more source

Synthesis of a Novel Thermoresponsive S53P4 Bioactive Glass Extract–Poloxamer 407 Injectable Hydrogels: Assessment of Biocompatibility and Antimicrobial Properties

Advanced Engineering Materials, EarlyView.
This study investigates innovative thermoreversible hydrogels derived from S53P4 bioactive glass extracts to aid in the healing of infected diabetic foot wounds. These injectable gels, which gel at body temperature, release beneficial ions and remain stable over time.
Marian G. Vargas Guerrero, Adrian Stiller, Alex Nygård, Matej Krivulka, Lars Galema, Erwin Peters, Jimmy Lucchesi, Peter Uppstu, Leena Hupa, Jacobus J. C. Arts   +9 more
wiley   +1 more source

Fructose-1,6-Bisphosphate Reduces Chronic Constriction Injury Neuropathic Pain in Mice by Targeting Dorsal Root Ganglia Nociceptive Neuron Activation

Pharmaceuticals
Background/Objectives: Fructose-1,6-bisphosphate (FBP) is an intermediate product of the glycolytic pathway with analgesic effect in acute inflammatory pain model via the production of adenosine.
Amanda Martins Dionisio, Paula de Azevedo Oliveira Milanez, Ana Carla Zarpelon-Schutz, Sandra Satie Mizokami, Mariana Marques Bertozzi, Kelly Megumi Yaekashi, Doumit Camilios-Neto, Sergio Marques Borghi, Rubia Casagrande, Waldiceu A. Verri   +9 more
doaj   +1 more source

Clinical Features and Genetic Analysis of Drug-resistant Epilepsy in Children [PDF]

Zhongguo quanke yixue
Background At present, the proportion of DRUG-RESISTANT epilepsy (DRE) in children is still maintained at about 30%, and it is often combined with mental retardation, affecting the quality of life, so the diagnosis and treatment of DRE is still a major ...
ZUO Ranran, SUN Suzhen
doaj   +1 more source