Results 61 to 70 of about 423,580 (268)

Peripheral neuropathy in prediabetes and the metabolic syndrome

open access: yesJournal of Diabetes Investigation, 2017
Peripheral neuropathy is a major cause of disability worldwide. Diabetes is the most common cause of neuropathy, accounting for 50% of cases. Over half of people with diabetes develop neuropathy, and diabetic peripheral neuropathy (DPN) is a major cause ...
A. Stino, A. G. Smith
semanticscholar   +1 more source

Evidence from web-based dietary search patterns to the role of B12 deficiency in chronic pain [PDF]

open access: yes, 2017
Profound vitamin B12 deficiency is a known cause of disease, but the role of low or intermediate levels of B12 in the development of neuropathy and other neuropsychiatric symptoms as well as the relationship of eating meat and B12 levels is unclear.
arxiv   +1 more source

Galectin-1 and galectin-3 as key molecules for peripheral nerve degeneration and regeneration

open access: yesAIMS Molecular Science, 2016
There is growing evidence that galectin-1 (GAL-1) and galectin-3 (GAL-3) are involved in the process of axonal regeneration after injury and the pathogenesis of peripheral neuropathies, but the precise roles of these galectins in the peripheral nervous ...
Hideji Yako   +8 more
doaj   +1 more source

Nicotinamide Riboside Opposes Type 2 Diabetes and Neuropathy in Mice

open access: yesScientific Reports, 2016
Male C57BL/6J mice raised on high fat diet (HFD) become prediabetic and develop insulin resistance and sensory neuropathy. The same mice given low doses of streptozotocin are a model of type 2 diabetes (T2D), developing hyperglycemia, severe insulin ...
Samuel A. J. Trammell   +9 more
semanticscholar   +1 more source

PARAPROTEINEMIC NEUROPATHIES

open access: yesJournal of the Peripheral Nervous System, 2001
The occurrence of a peripheral neuropathy (PN) in association with a monoclonal gammopathy is quite common and suggests that monoclonal proteins may play a pathogenetic role in peripheral nervous system damage. In fact, paraproteinemic PN constitute an heterogeneous group of disorders related to various pathogenetic factors, and the histopathologic ...
openaire   +3 more sources

The Pain in Neuropathy Study (PiNS): a cross-sectional observational study determining the somatosensory phenotype of painful and painless diabetic neuropathy

open access: yesPain, 2016
Disabling neuropathic pain (NeuP) is a common sequel of diabetic peripheral neuropathy (DPN). We aimed to characterise the sensory phenotype of patients with and without NeuP, assess screening tools for NeuP, and relate DPN severity to NeuP.
Andreas C Themistocleous   +8 more
semanticscholar   +1 more source

Neuropathy in diabetes

open access: yesMedicine, 2006
Diabetic polyneuropathy affects 30–50% of patients with diabetes mellitus. It encompasses several neuropathic syndromes, the commonest being distal symmetrical polyneuropathy or ‘diabetic peripheral neuropathy’ (DPN). Risk factors for DPN include poor glycaemic control and drivers of macrovascular disease including hypertension.
openaire   +2 more sources

Diabetic Neuropathy [PDF]

open access: yesDiabetes Care, 2007
Perspectives on the News commentaries are now part of a new, free monthly CME activity. The Mount Sinai School of Medicine, New York, New York, is designating this activity for 2.0 AMA PRA Category 1 credits. If you wish to participate, review this article and visit www.diabetes.procampus.net to complete a posttest and receive a certificate.
openaire   +4 more sources

Budlein A, a Sesquiterpene Lactone From Viguiera robusta, Alleviates Pain and Inflammation in a Model of Acute Gout Arthritis in Mice

open access: yesFrontiers in Pharmacology, 2018
Background: Gout is the most common inflammatory arthritis worldwide. It is a painful inflammatory disease induced by the deposition of monosodium urate (MSU) crystals in the joints and peri-articular tissues.
Victor Fattori   +11 more
doaj   +1 more source

Long-term neuropathy and quality of life in colorectal cancer patients treated with oxaliplatin containing adjuvant chemotherapy

open access: yesActa oncologica, 2019
Background: Oxaliplatin, combined with capecitabine (CAPOX) or infused 5-fluorouracil (FOLFOX), is standard of care in the adjuvant treatment of colorectal cancer (CRC). Prospective data on prevalence of oxaliplatin induced acute and long-term neuropathy
L. Soveri   +5 more
semanticscholar   +1 more source

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