Results 131 to 140 of about 2,671,723 (284)

Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers, Zachery R. Gregorich, Megan S. Gant, Zhan Gao, Julia Chamot‐Rooke, Ying Ge   +5 more
wiley   +1 more source

A Randomized Controlled Trial of Dual Upper‐Extremity Training [DUET]: Combining Neurologic Music Therapy® with Noninvasive Brain Stimulation for Upper‐Limb Performance in Corticobasal Syndrome

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Corticobasal syndrome (CBS) is a progressive neurodegenerative condition characterized by asymmetric limb rigidity, apraxia, dystonia, and myoclonus, with no approved symptomatic or disease‐modifying drug treatments. Neurologic music therapy (NMT)® employs evidence‐based techniques targeting sensorimotor rehabilitation, and high ...
Kyurim Kang, Isabella Sterner, Shriya Bakhshi, Chris Bedell, Alexander Pantelyat   +4 more
wiley   +1 more source

Defining the Clinical Phenotypic Ground Truth: Expert Interrater Agreement in Hyperkinetic Movement Disorders

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Reliable clinical phenotyping is crucial for diagnosis, treatment, and research in hyperkinetic movement disorders, yet its interrater reliability remains uncertain. Objectives To quantify interrater agreement in clinical phenotyping of hyperkinetic movement disorders among experts in a large, phenotypically diverse cohort.
Madelein van der Stouwe, Olof Vermeulen, Wieke Eggink, Tove Henriksen, Eavan McGovern, Marenka Smit, Selma Aybek, Agnita Boon, Rick Brandsma, Andres Deik, Roberto Erro, Alberto Espay, Cristian Falup‐Pecurariu, Stephen Frucht, Christos Ganos, Emilia Gatto, Rick Helmich, Christine Klein, Hans Koelman, Vincent Odekerken, Lisette Koens, Abhimanyu Mahajan, Francesca Morgante, Alexander Münchau, Pattamon Panyakaew, Kathryn Peall, Bélen Pérez‐Dueñas, Emanuel Roze, Anna Sadnicka, Susanne Schneider, Petra Schwingenschuh, Tereza Serranova, Matej Skorvanek, Maria Stamelou, Gertrúd Tamas, Michele Tinazzi, Anna Valadas, Wim Vandenberghe, Jeroen de Vries, Rodi Zutt, Sterre van der Veen, Rogier Luiken, Inge Tuitert, Marina Tijssen   +43 more
wiley   +1 more source

Neurophysiologic monitoring for treatment of upper lumbar disc herniation with percutaneous endoscopic lumbar discectomy: A case report on the significance of an increase in the amplitude of motor evoked potential responses after decompression and literature review. [PDF]

Int J Surg Case Rep, 2020
He S, Ren Z, Zhang X, Li J.
europepmc   +1 more source

Dissociable Handwriting Domains in Parkinson's Disease?

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Handwriting abnormalities in Parkinson's disease (PD) extend beyond classical micrographia and may involve multiple graphomotor domains with distinct clinical and mechanistic correlates. Objectives To investigate whether distinct handwriting domains demonstrate dissociable relationships with differential diagnostic performance ...
Beyza Nur Cetin, Selcuk Comoglu, Aycan Cemil Ulker, Halil Onder   +3 more
wiley   +1 more source

Wearable Evidence Linking Dyskinesia Burden to Sleep Quality in Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Sleep disturbances affect 60–80% of people with Parkinson's disease (PD) and worsen quality of life. Dyskinesia is a common complication of dopaminergic therapy, yet its link to sleep quality is poorly understood. Objectives To examine whether clinician‐rated and objectively measured dyskinesia are associated with sleep quality in ...
Viktoria Azoidou, Essa Bhadra, Ellen Camboe, Kamalesh C. Dey, Alexandra Zirra, Kira Rowsell, Corrine Quah, Caroline Budu, Thomas Boyle, David Gallagher, Jonathan P. Bestwick, Laura Pérez‐Carbonell, Alastair J. Noyce, Cristina Simonet   +13 more
wiley   +1 more source

Census Monitoring Board Presidential Members

, 1999
U.S. Census Monitoring Board is a bipartisan board charged with monitoring the Bureau of the Census' preparations for the 2000 Census and reporting its findings to Congress and the ...
U.S. Census Monitoring Board Presidential Members
core  

A Gap Analysis of Deep Brain Stimulation for Childhood‐Onset Movement Disorders

Movement Disorders, EarlyView.
Abstract Background Deep brain stimulation (DBS) is an established and increasingly utilized therapy for childhood‐onset movement disorders. However, pediatric DBS poses unique challenges that are not adequately addressed by adult‐derived paradigms. Objective To identify key gaps in the current use of DBS in childhood‐onset movement disorders and to ...
Daniela Munoz‐Chesta, Carolina Gorodetsky, Todd M. Herrington, Angela L. Hewitt, Daniel E. Lumsden, Jennifer O'Malley, Terence Sanger   +6 more
wiley   +1 more source

Why Use Immersive Virtual Reality to Assess Gait in Functional Motor Disorders?

Movement Disorders, EarlyView.
Abstract Background Functional motor disorders (FMD) are disabling conditions modulated by attentional demands. Immersive virtual reality (iVR) engages multiple attentional and sensory networks, but its application in people with FMD (PwFMD) remains limited.
Marialuisa Gandolfi, Chiara Bonetto, Corrado Perin, Angela Sandri, Giulia Bonardi, Ilaria Antonella Di Vico, Laura Avanzino, Elisa Pelosin, Mauro Crestani, Christian Geroin, Denis Vidale, Marco Pirini, Mirta Fiorio, Michele Tinazzi, Francesca Salaorni   +14 more
wiley   +1 more source

Surgeon-driven neurophysiologic monitoring in a spinal surgery population. [PDF]

J Spine Surg, 2016
Pickell M, Mann SM, Chakravertty R, Borschneck DP.   +3 more
europepmc   +1 more source