Results 141 to 150 of about 2,671,723 (284)

Apathy in Lewy Body Disorders: A Position Paper

open access: yesMovement Disorders, EarlyView.
Abstract Apathy is one of the most prevalent and disabling non‐motor symptoms in Parkinson's disease (PD) and dementia with Lewy bodies (DLB), collectively referred to as Lewy body disorders (LBDs). It is associated with reduced quality of life, accelerated cognitive decline, increased caregiver burden, and poorer functional outcomes, yet remains ...
Jaime Kulisevsky   +12 more
wiley   +1 more source

Decoding Sleep Architecture from Ambulatory Basal Ganglia Signals in Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Background Sleep architecture and circadian rhythms are frequently disrupted in Parkinson's disease (PD). BrainSense‐enabled neurostimulators combined with wearable technology enable chronic assessment of nocturnal brain activity, with potential for future diagnostics and personalized treatments. Objectives To neurophysiologically characterize
Alberto Averna   +15 more
wiley   +1 more source

Multimodal Magnetic Resonance Imaging and Machine Learning Uncovers Distinct Progression Patterns in Friedreich Ataxia

open access: yesMovement Disorders, EarlyView.
Abstract Background Friedreich ataxia (FRDA) is a rare neurodegenerative disorder with heterogenous clinical progression, complicating prognosis and trial design. Neuroimaging offers objective biomarkers of disease progression, yet variability in progression patterns remains poorly understood.
Susmita Saha   +8 more
wiley   +1 more source

A Systematic Review of the Safety and Tolerability of Theta Burst Stimulation in Children and Adolescents

open access: yesNeuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives Theta burst stimulation (TBS) is often used in clinical practice and research protocols for adults with neuropsychiatric disorders. There are substantial knowledge gaps related to the application of TBS in children and adolescents.
Rana Elmaghraby   +5 more
wiley   +1 more source

Thrombotic thrombocytopenic purpura: prospective neurologic, neuroimaging and neurophysiologic evaluation

open access: yesHaematologica, 2001
BACKGROUND AND OBJECTIVES: Neurologic symptoms are present in 60% of patients with thrombotic thrombocytopenic purpura (TTP) on initial examination and ultimately develop in about 90% of cases during the course of the disease.
G Meloni   +9 more
doaj  

Early and Extensive Degeneration of Sensory Neurons in Spinocerebellar Ataxia Type 3

open access: yesMovement Disorders, EarlyView.
Abstract Background Postmortem studies have shown significant degeneration of the peripheral nervous system (PNS) in spinocerebellar ataxia type 3 (SCA3). Although PNS involvement accelerates overall ataxia progression, PNS biomarkers for therapeutic trials are lacking and our mechanistic understanding of related clinical manifestations remains ...
Milou Baarsma   +3 more
wiley   +1 more source

Local Field Potential‐Based Programming: A Proof‐of‐Concept Pilot Study

open access: yesNeuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives Programming deep brain stimulation (DBS) is still based on a trial‐and‐error approach, often becoming a time‐consuming process for both treating physicians and patients. Several strategies have been proposed to streamline DBS programming, most of which are preliminary and mainly address Parkinson's disease, a condition readily ...
Alfonso Fasano   +10 more
wiley   +1 more source

Diagnostic Accuracy of Intraoperative Neurophysiologic Monitoring in Spinal Deformity Surgery: Systematic Review and Meta-Analysis. [PDF]

open access: yesGlobal Spine J
O'Reilly BT   +14 more
europepmc   +1 more source

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