ABSTRACT This study addresses the need to understand human engagement with empathic Generative Artificial Intelligence (GenAI) digital companions (DC), as these systems increasingly fulfil social and emotional roles in daily life. Motivated by the rapid adoption of DC technologies and their potential to reshape human–AI relationships, the study applies
Aitor Ezker‐Galech +3 more
wiley +1 more source
Total Intravenous Anesthesia for Intraoperative Neurophysiological Monitoring in a Child With Diastematomyelia: A Case Report. [PDF]
Sabesan T +4 more
europepmc +1 more source
Proteoforms in Disease: Biomedical Applications of Top‐Down Proteomics
ABSTRACT The proteome is a dynamic landscape of proteoforms arising from genetic mutations, alternative splicing, and post‐translational modifications (PTMs), which collectively drive biological function and disease phenotypes. Mass spectrometry (MS)‐based proteomics has emerged as an essential technique for elucidating this molecular complexity ...
Holden T. Rogers +5 more
wiley +1 more source
Abstract Background Corticobasal syndrome (CBS) is a progressive neurodegenerative condition characterized by asymmetric limb rigidity, apraxia, dystonia, and myoclonus, with no approved symptomatic or disease‐modifying drug treatments. Neurologic music therapy (NMT)® employs evidence‐based techniques targeting sensorimotor rehabilitation, and high ...
Kyurim Kang +4 more
wiley +1 more source
The potential impact of intraoperative neurophysiological monitoring on neurological function outcomes after postnatal spina bifida repair. [PDF]
Krause M +5 more
europepmc +1 more source
Dissociable Handwriting Domains in Parkinson's Disease?
Abstract Background Handwriting abnormalities in Parkinson's disease (PD) extend beyond classical micrographia and may involve multiple graphomotor domains with distinct clinical and mechanistic correlates. Objectives To investigate whether distinct handwriting domains demonstrate dissociable relationships with differential diagnostic performance ...
Beyza Nur Cetin +3 more
wiley +1 more source
The Value of Intraoperative Neurophysiological Monitoring During Patient Positioning in Spine Surgery: A Preventive Strategy. [PDF]
Rebelo P, Sousa CP, Campos MT.
europepmc +1 more source
A Gap Analysis of Deep Brain Stimulation for Childhood‐Onset Movement Disorders
Abstract Background Deep brain stimulation (DBS) is an established and increasingly utilized therapy for childhood‐onset movement disorders. However, pediatric DBS poses unique challenges that are not adequately addressed by adult‐derived paradigms. Objective To identify key gaps in the current use of DBS in childhood‐onset movement disorders and to ...
Daniela Munoz‐Chesta +6 more
wiley +1 more source
Current trends in intraoperative neurophysiological monitoring among Asia-Pacific countries: an Asia-Pacific Spine Society survey. [PDF]
Shigematsu H +13 more
europepmc +1 more source
Abstract Aims To conduct a case–control study to investigate melanopsin‐mediated post‐illumination pupillary response (PIPR) in patients with Parkinson's disease (PD), video‐polysomnography‐confirmed isolated/idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD), and age‐matched healthy controls (HC). Methods PIPR was measured at 6 s after
Joey W.Y. Chan +16 more
wiley +1 more source

