Results 151 to 160 of about 207,140 (324)

Sex Differences in Associations of Lewy Body Disease with Alzheimer's Disease and Cognitive Decline

open access: yesAnnals of Neurology, EarlyView.
Objective To investigate how sex and age at menopause influence the interplay between Alzheimer's disease (AD) and Lewy body disease (LBD) neuropathologies, and their associations with cognitive decline. Methods We analyzed data from: (1) three Rush Alzheimer's Disease Center cohorts (i.e., the Religious Orders Study, Rush Memory and Aging Project, and
Madeline Wood Alexander   +17 more
wiley   +1 more source

Volumetric MRI Comparing Longitudinal Change in MOGAD to NMOSD, MS and Healthy Controls, and Disability Associations

open access: yesAnnals of Neurology, EarlyView.
Objectives To examine volumetric magnetic resonance imaging (vMRI) in myelin oligodendrocyte glycoprotein antibody‐associated disease (MOGAD), compared to multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and healthy controls (HC). Methods Standardized vMRI in MOGAD were compared to age, sex, and disease duration matched MS (5:1),
Amy Kunchok   +10 more
wiley   +1 more source

Widespread Skin Telangiectasias in Spinocerebellar Ataxia Type 27B

open access: yes
Annals of Neurology, EarlyView.
Victor Alm   +3 more
wiley   +1 more source

Subthalamic Electrophysiological Mapping of Gait Initiation Dynamics and Freezing in Parkinson's Disease

open access: yesAnnals of Neurology, EarlyView.
Objective The objective of this study was to investigate the relationships among subthalamic nucleus (STN) activity, gait initiation (GI), and freezing of gait (FOG) in patients with Parkinson's disease (PD). Methods We recorded GI and STN local field potentials (LFPs) via externalized cables in 38 patients with PD (35 reporting FOG in daily life ...
Antoine Collomb‐Clerc   +12 more
wiley   +1 more source

Exenatide Once Weekly in the Treatment of Patients with Multiple System Atrophy

open access: yesAnnals of Neurology, EarlyView.
Objective Exenatide, a glucagon‐like peptide‐1 (GLP‐1) receptor agonist, has neuroprotective effects in preclinical models of multiple system atrophy (MSA). We investigated these effects in a proof‐of‐concept clinical trial. Methods In this single‐center, randomized, open label trial, participants with MSA were randomly assigned (1:1) to receive ...
Nirosen Vijiaratnam   +29 more
wiley   +1 more source

Frequency of Microvascular Pathology and Hippocampal Atrophy on Magnetic Resonance Imaging in a Community Study of Alzheimer's Disease with Blood‐Based Biomarkers

open access: yesAnnals of Neurology, EarlyView.
Objective Blood‐based biomarkers for Alzheimer's disease (AD), representing antemortem indicators of AD pathophysiology, have greatly improved the accuracy of diagnosis. However, these biomarkers may not capture a frequent coincident pathology, such as cerebrovascular disease.
Tamil Iniyan Gunasekaran   +12 more
wiley   +1 more source

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