Soticlestat as adjunctive therapy for Lennox–Gastaut syndrome. Abstract Objective There remains a need for new treatments for Lennox–Gastaut syndrome (LGS), a developmental and epileptic encephalopathy with a heterogenous patient population that often requires polytherapy. The phase 3, randomized SKYWAY study (NCT04938427) investigated the efficacy and
Renzo Guerrini +15 more
wiley +1 more source
A symphony of functioning: exploring the interplay of cognition, movement, and visual demands in adolescents on the autism spectrum using mobile brain-body imaging (MoBI). [PDF]
Nicklas PR +7 more
europepmc +1 more source
Abstract Objective Nonconvulsive epileptic activity is common after acute brain injury and contributes to neuronal injury and poor outcomes. Although intracranial electroencephalography (iEEG) improves detection compared with surface EEG (suEEG), it currently relies on focal recordings of epileptic dynamics.
Steven Smeijers +7 more
wiley +1 more source
Timing matters when using paraclinical tests to assess for optic neuritis under the 2024 McDonald criteria. [PDF]
Jia FF, Ng K.
europepmc +1 more source
Abstract Objective Neonatal developmental and epileptic encephalopathy with movement disorder and arthrogryposis (NDEEMA) represents the most severe end of the gain‐of‐function (GOF) SCN1A disorder spectrum. Sporadic cases of congenital arthrogryposis have also been reported in individuals with SCN2A‐, SCN3A‐, and SCN8A‐related developmental and ...
Sopio Gverdtsiteli +43 more
wiley +1 more source
Letter to the editor regarding "Electrophysiological monitoring of the trigeminal nerve sensory root using sensory-masseter response for microvascular decompression in trigeminal neuralgia". [PDF]
Riaz M, Grassia F.
europepmc +1 more source
Peripheral Neuropathy Expands the Neurological Phenotype in Glutaric Aciduria Type 1. [PDF]
Preisner F +8 more
europepmc +1 more source
Reply to “Perception of Lower Extremity Loading in Stroke” [PDF]
Chu, Virginia W. +2 more
core +1 more source
The Adherence to Anti-seizure Medications in Adolescents is Complex and Requires Consideration of All Influencing Factors. [PDF]
Finsterer J.
europepmc +1 more source

