Results 231 to 240 of about 123,545 (372)

Neurocognitive and Neuroplastic Mechanisms of Novel Clinical Signs in CRPS [PDF]

open access: gold, 2016
Anoop Kuttikat   +5 more
openalex   +1 more source

A PK/PD study on antihyperalgesia by an α2/3‐GABAA receptor PAM in mice: Lack of tolerance liability and potential involvement of γ1‐GABAA receptors

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose GABAA receptors (GABAARs) are heteropentameric ion channels that control almost all CNS functions, including spinal nociception. Most GABAARs contain a γ2 subunit but differ in their α and β subunit composition. TPA023B is an α2/α3 subtype selective, non‐sedative, positive allosteric modulator (PAM) with antihyperalgesic
Elena Neumann   +12 more
wiley   +1 more source

Enhanced neural plasticity of the primary visual cortex in visual snow syndrome: evidence from magnetoencephalographic gamma oscillations. [PDF]

open access: yesBrain Commun
Orekhova EV   +7 more
europepmc   +1 more source

Intermittent metabolic switching, neuroplasticity and brain health

open access: yesNature Reviews Neuroscience, 2018
M. Mattson   +4 more
semanticscholar   +1 more source

Epigenetic mechanisms and therapeutic innovations in chronic pain‐associated neuropsychiatric co‐morbidities

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang   +18 more
wiley   +1 more source

Huntingtin in the amygdaloid basolateral complex is correlated with Vonsattel staging in Huntington's disease. [PDF]

open access: yesBrain Commun
Sanchez-Migallon P   +10 more
europepmc   +1 more source

Stress Induced Neuroplasticity and Mental Disorders 2018 [PDF]

open access: gold, 2018
Fushun Wang   +3 more
openalex   +1 more source

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

open access: yesBritish Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman   +3 more
wiley   +1 more source

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