Results 291 to 300 of about 174,618 (333)

Neuroprotective Mechanisms of <i>Red Algae</i>-Derived Bioactive Compounds in Alzheimer's Disease: An Overview of Novel Insights. [PDF]

Mar Drugs
Wang T, Shi W, Mao Z, Xie W, Wan G.
europepmc   +1 more source

CCR5 predicts neurotoxicity in CAR‐T‐cell therapy

British Journal of Haematology, EarlyView.
Patients undergoing chimeric antigen receptor T (CAR T)‐cell therapy are at risk of developing immune effector cell‐associated neurotoxicity syndrome (ICANS). We observed an upregulation of CCR5 and CCR2 expression in CD4+ T cells among patients who developed ICANS.
Ayal Rozenberg, Shahar Shelly, Raz Winer, Riva Fineman, Shani Haller, Shimrit Ringelstein‐Harlev, Israel Henig, Dana Yehudai‐Ofir, Tsila Zuckerman, Tamar Tadmor, Reut Harel, Esther Ganelin‐Cohen, Ofrat Beyar‐Katz   +12 more
wiley   +1 more source

A new taxonomy of neuroprotective agents for stroke appropriate for the reperfusion era. [PDF]

Front Neurol
Bahr-Hosseini M, Saver JL.
europepmc   +1 more source

Human amyotrophic lateral sclerosis/motor neuron disease: The disease‐associated microglial pathway is upregulated while APOE genotype governs risk and survival

Brain Pathology, EarlyView.
ALS/MND‐related inflammation is investigated in the motor cortex and spinal cord by both transcriptomics and immunohistochemistry. This reveals greater inflammation in the spinal cord and highlights the disease‐associated microglial (DAM) phenotype characterized by ApoE, TREM2, and TYROBP.
Bridget A. Ashford, Julie E. Simpson, Charlotte Dawson, Delphine Boche, Johnathan Cooper‐Knock, Paul R. Heath, Daniel Fillingham, Charlie Appleby‐Mallinder, Wenbin Wei, Mark Dunning, J. Robin Highley   +10 more
wiley   +1 more source

Mitigating the impact of mechanisms causing neuronal degeneration

Neuroprotection
Xunming Ji, Piotr Walczak, Johannes Boltze   +2 more
doaj   +1 more source

Editorial: Targeting neuroinflammation for novel therapeutics in neurodegenerative diseases. [PDF]

Front Pharmacol
Khanal P, Chikhale R, Machhi J.
europepmc   +1 more source

The physiological and pathological effects of sphingolipid metabolism and signaling in the central nervous system

Brain Pathology, EarlyView.
Sphingolipids are vital components of cell membranes. Metabolic disruptions of sphingolipids, including ceramide and sphingosine‐1‐phosphate, are linked to neurological disorders. This article summarizes the classification, structure, and metabolic processes of sphingolipids, and the physiological and pathological effects of sphingolipid metabolism and
Tian Li, Haoying He, Ejuan Zhang, Fengjiao Hu, Zhuo Wang, Jian Xu, Mengliu Zeng, Biwen Peng   +7 more
wiley   +1 more source

Histone Acetylation in Central and Peripheral Nervous System Injuries and Regeneration: Epigenetic Dynamics and Therapeutic Perspectives. [PDF]

Int J Mol Sci
Palomés-Borrajo G, Navarro X, Penas C.
europepmc   +1 more source

From vulnerability to resilience: unraveling the role of oxidative stress in preterm brain injury. [PDF]

Ital J Pediatr
Jiang Q, Wen J, Ding Y, Cui H.
europepmc   +1 more source