Quinones as Neuroprotective Agents [PDF]
Antioxidants, 2023 Quinones can in principle be viewed as a double-edged sword in the treatment of neurodegenerative diseases, since they are often cytoprotective but can also be cytotoxic due to covalent and redox modification of biomolecules.
Ángel Cores +4 more
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Neuroprotective Agents with Therapeutic Potential for COVID-19 [PDF]
Biomolecules, 2023 COVID-19 patients can exhibit a wide range of clinical manifestations affecting various organs and systems. Neurological symptoms have been reported in COVID-19 patients, both during the acute phase of the illness and in cases of long-term COVID ...
César A. Zaa +4 more
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Fiscalin Derivatives as Potential Neuroprotective Agents [PDF]
Pharmaceutics, 2022 Neurodegenerative diseases (ND) share common molecular/cellular mechanisms that contribute to their progression and pathogenesis. In this sense, we are here proposing new neuroprotection strategies by using marine-derived compounds as fiscalins.
Sandra Barreiro +6 more
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Thiourea-Based H2S-Releasing Pramipexole Hybrids as Neuroprotective Agents [PDF]
AntioxidantsMultitarget hybrid molecules are a promising strategy for treating complex neurodegenerative disorders such as Parkinson’s disease (PD), where dopaminergic dysfunction, oxidative stress, neuroinflammation, and cellular senescence coexist and drive ...
Angela Corvino +12 more
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Carbon nanotubes as neuroprotective agents [PDF]
Exploration of Neuroprotective TherapyCarbon nanotubes, an emerging class of carbon nanomaterials, possess tremendous potential for application in biotechnology and biomedicine particularly in neurological disorders.
Daisy L. Wilson +2 more
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Mining and evaluation of security alert signals of neuroprotective agents based on the Jinan adverse event reporting system database: a retrospective study [PDF]
Frontiers in PharmacologyBackgroundPharmacologic agents with proposed neuroprotective properties are increasingly investigated; however, limited regulation and heterogeneous evidence raise concerns about their safety profiles. To establish a foundation for its safe clinical use,
Yu-yao Guan +4 more
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Comparative efficacy of neuroprotective agents for improving neurological function and prognosis in acute ischemic stroke: a network meta-analysis [PDF]
Frontiers in NeuroscienceBackgroundIschemic stroke is the second leading cause of death and the third leading cause of combined disability and mortality globally. While reperfusion therapies play a critical role in the management of acute ischemic stroke (AIS), their ...
Yuchen Wang +6 more
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2024 international conference on neuroprotective agents conference proceedings [PDF]
Experimental Biology and MedicineWilliam Slikker +3 more
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Therapeutic potential of agmatine in the experimental autoimmune encephalomyelitis [PDF]
Vojnosanitetski Pregled, 2021 Background/Aim. Experimental autoimmune encephalomyelitis (EAE) is a model of multiple sclerosis (MS), in which we investigated the neuroprotective effect of agmatine (AGM), known as a primary amine produced via the decarboxylation of L-arginine. Methods.
Stevanović Ivana +4 more
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Exploration of Neuroprotective Therapy, 2023 Acute ischemic stroke (AIS) is the leading cause of disability and one of the top causes of mortality worldwide. The current standard of care is reperfusion therapy including intravenous thrombolysis (IVT) and thrombectomy. However, these treatments have
Grace YY Chia +5 more
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