Results 41 to 50 of about 88,263 (338)
Разработка и регистрация лекарственных средств, 2021 Introduction. The search for and development of new drugs capable of reducing the severity of neurological deficit in traumatic brain injury are a critical task for investigational pharmacology.
V. A. Prikhodko +5 more
doaj +1 more source
Lichens of Parmelioid Clade as Promising Multitarget Neuroprotective Agents
, 2019 Neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease are multifactorial disorders which are increasing in incidence and prevalence over the world without existing effective therapies.
Dulare Devi, Pradeep Divakar +4 more
core +1 more source
Anthocyanins: Plant-based flavonoid pigments with diverse biological activities
International Journal of Plant Based Pharmaceuticals, 2022 Anthocyanins are flavonoid containing polyphenolic phytochemicals. They are widely present in plants and accounts for different color shades displayed by the plant organs.
Sandip Patra +4 more
doaj
Frontiers in Neurology, 2020 There are virtually no clinically available neuroprotective drugs for the treatment of acute and chronic neurological disorders, hence there is an urgent need for the development of new neuroprotective molecules.
Bruno P. Meloni +7 more
doaj +1 more source
Are Kynurenines Accomplices or Principal Villains in Dementia? Maintenance of Kynurenine Metabolism
Molecules, 2020 Worldwide, 50 million people suffer from dementia, a group of symptoms affecting cognitive and social functions, progressing severely enough to interfere with daily life.
Masaru Tanaka +2 more
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, Volume 20, Issue 6, Page 1398-1419, June 2026.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Potential Role of Olive Oil Phenolic Compounds in the Prevention of Neurodegenerative Diseases
Molecules, 2015 Adherence to the Mediterranean Diet (MD) has been associated with a reduced incidence of neurodegenerative diseases and better cognitive performance.
Jose Rodríguez-Morató +5 more
doaj +1 more source
Current neuroprotective agents in stroke [PDF]
Turk J Phys Med RehabilWhat is expected from neuroprotection is to inhibit neuronal death and halt or decelerate the neuronal loss to lower the mortality rates, decrease disability, and improve the quality of life following an acute ischemic stroke. Several agents were described as neuroprotective up to date; however, there is still debate which to use in the ...
Yanık T, Yanık B.
europepmc +3 more sources
A Review of Agents Patented for their Neuroprotective Properties
, 2006 The brain continues to remain an area where little corrective surgery can be performed. Recently, the ability to reverse some brain damage and perhaps prevent further damage has moved closer to hospitals and clinics.
Levi, MS, Brimble, Margaret
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Molecular Oncology, Volume 20, Issue 6, Page 1591-1611, June 2026.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source