Results 51 to 60 of about 1,639,688 (287)
A Review of Agents Patented for their Neuroprotective Properties
, 2006 The brain continues to remain an area where little corrective surgery can be performed. Recently, the ability to reverse some brain damage and perhaps prevent further damage has moved closer to hospitals and clinics.
Levi, MS, Brimble, Margaret
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Possible Neuroprotective Therapy for Parkinson's Disease [PDF]
, 1995 Neuroprotective therapy for Parkinson's disease (PD) is a treatment intended to prevent or reduce neuronal degeneration. Since clinical studies to evaluate such an effect would be prolonged, the choice of agents for use as possible neuroprotective ...
Ogawa, Norio
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Discovery of neuroprotective agents that inhibit human prolyl hydroxylase PHD2 [PDF]
, 2021 Prolyl hydroxylase (PHD) enzymes play a critical role in the cellular responses to hypoxia through their regulation of the hypoxia inducible factor α (HIF-α) transcription factors.
Weissberger, Daniel +7 more
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Ischemic stroke, a major cause of mortality and long‐term disability, results from the abrupt cessation of cerebral blood flow due to vascular occlusion or rupture. Icosapent Ethyl (EPA‐EE), approved for hypertriglyceridemia, has anti‐inflammatory and antithrombotic properties that may lessen ischemic damage.
Mitra Mahmoudi Meymand +5 more
wiley +1 more source
Poststroke cognitive impairment and dementia
Медицинский совет, 2016 Post-stroke cognitive impairment and dementia are one of the major causes of the disability and quality of life deterioration following cerebrovascular accident. In this review we cover current views on the prevalence, mechanisms and risk factors of post-
D. V. Sergeev +2 more
doaj +1 more source
Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son +3 more
wiley +1 more source
Synthesis of Fluoroflavones as Potential Neuroprotective Agents [PDF]
, 2019 Flavones are polyphenol natural products that are known to have neuroprotective effects against many diseases caused by the formation of reactive species. Flavonoids are subgroup of flavones and they are believed to function as antioxidants. Specifically,
Alshammari, Maali
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Effect of nicotine on the energy metabolism of substantia nigra cells in mptp-induced Parkinson’s disease [PDF]
Iranian Journal of Basic Medical SciencesObjective(s): Parkinson’s disease (PD) is a progressive neurodegenerative disorder affecting millions globally, with no current cure despite extensive research efforts.
Nikoloz Zhgenti +6 more
doaj +1 more source
Разработка и регистрация лекарственных средств, 2021 Introduction. The search for and development of new drugs capable of reducing the severity of neurological deficit in traumatic brain injury are a critical task for investigational pharmacology.
V. A. Prikhodko +5 more
doaj +1 more source
Chronic Hypertension Aggravates Heat Stress–Induced Cognitive Dysfunction and Brain Pathology
, 2007 Hyperthermia following heat stress results in profound brain edema formation and damage to the central nervous system (CNS). However, whether acute or chronic diseases such as cardiovascular, endocrine, or metabolic ailments further influence the ...
Sharma, Hari S, +3 more
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