Results 11 to 20 of about 305 (106)

Baseline Results Investigate APOE‐Memory Connection in Latin‐American Population at Risk for Dementia ‐ LatAm‐FINGERS Initial Insights [PDF]

Alzheimers Dement
Abstract Background Latin America (LA) faces heightened vulnerability to modifiable dementia risk factors. Early identification of at‐risk individuals is crucial for implementing effective preventive strategies. The Free and Cued Selective Reminding Test with Immediate Recall (FCSRT‐IR) is promising in early detection of mnemonic impairment, with high ...
Friedlaender C, de Souza L, Barbosa M, Gomes K, Tosatti J, de Faria Rocha J, Cardoso D, Prates M, Lopes A, Vieira V, Jeunon V, de Souza L, Figueiredo L, de Andrades A, Teixeira D, Sosa A, Nitrini R, Allegri R, Sevlever G, Niño D, Acosta D, Crivelli L, Charamelo A, Jimenez‐Velazquez I, Custodio N, Duque L, Leon‐Salas J, Delgado C, Cusicanqui M, Custodio B, Salinas‐Contreras R, Cançado G, Vigil‐Martinez A, Martin M, Damian A, Surace E, Acosta‐Baena N, Calandri I, Yassuda M, Suemoto C, Martin M, Brucki S, Snyder H, Carrillo M, Kivipelto M, Caramelli P.   +45 more
europepmc   +2 more sources

Executive Functions in Latin American Older Adults: Exploring the Concept Shifting Test and Its Relationship with the APOE Gene in a Cross‐Sectional Sample from the LatAm‐FINGERS Study [PDF]

Alzheimers Dement
Abstract Background Latin America (LA) faces high vulnerability to dementia risk factors. Early detection of cognitive decline, particularly in executive functions (EF), is crucial. The Trail Making Test (TMT) has limitations, while the Concept Shifting Test (CST) offers potential advantages but lacks LA adaptation.
Cardoso D, Friedlaender C, Yassuda M, de Souza L, Crivelli L, Suemoto C, Martin M, Calandri I, Acosta‐Baena N, Surace E, Damian A, Martin M, Vigil‐Martinez A, Cançado G, Salinas‐Contreras R, Custodio B, Cusicanqui M, Delgado C, Leon‐Salas J, Duque L, Custodio N, Velazquez I, Charamelo A, Acosta D, Niño D, Sevlever G, Allegri R, Nitrini R, Sosa A, Gomes K, de Andrades A, Teixeira D, Figueiredo L, de Souza L, Jeunon V, Barbosa M, Vieira V, Lopes A, de Faria Rocha J, Prates M, Tossati J, Brucki S, Snyder H, Carrillo M, Kivipelto M, Caramelli P.   +45 more
europepmc   +2 more sources

Recommendations for genetic counseling for individuals at risk of autosomal dominant Alzheimer's disease in Latin America. [PDF]

Alzheimers Dement
Abstract Autosomal dominant Alzheimer's disease (ADAD) represents a small but impactful subset of Alzheimer's cases. Asymptomatic individuals at genetic risk face substantial personal and family implications when considering predictive testing for known familial variants.
Jiménez DA, Bagnati PM, Flores-Montes RE, Fernández ML, Zuno-Reyes A, Aguillon D, Alaez-Verson C, Becerra-Solano LE, Behrens MI, Branda K, Chrem P, Custodio N, Ducaine W, Dumois-Petersen S, Figuera L, Castaño ML, Longoria EM, Matute E, Sánchez V, Slachevsky A, Sosa AL, Surace E, Takada L, Yaeger L, Ziegemeier E, Guerra JJL, Programa de asesoramiento genético en América Latina (PRAGA).   +26 more
europepmc   +2 more sources

The relationship between amyloid‐b and cognition in young‐onset Mild Cognitive Impairment: the influence of disease duration [PDF]

Alzheimers Dement
Abstract Background The effect of amyloid‐b brain deposition on cognition is still debated, since it has been shown that its accumulation begins almost 15 years before cognitive symptoms' onset, then reaches a plateau while cognition continues to decline. We studied if there is a parallel between amyloid‐b deposition and cognitive performances in young‐
Carbone C, Balboni E, Beltrami D, Tondelli M, Gallingani C, Gasparini F, Salvatori D, Salemme S, Vinceti G, Fraternali A, Marti A, Chiari A, Zamboni G.   +12 more
europepmc   +2 more sources

Markers of atrophy progression in patients with young‐onset cognitive complaints not due to Alzheimer’s Disease [PDF]

Alzheimers Dement
Abstract Background In clinical settings, the prognosis of patients with subtle cognitive complaints and no imaging evidence of neurodegeneration is often challenging, especially in conditions unrelated to Alzheimer’s Disease (AD). We aimed to identify which baseline indicators can help in the clinical decision‐making process of patients with ...
Carbone C, Balboni E, Luchetti L, Urbano T, Beltrami D, Maramotti R, Tondelli M, Gallingani C, Gasparini F, Vinceti G, Marti A, Chiari A, Zamboni G.   +12 more
europepmc   +2 more sources

Exploring Social Networks in the LatAmFINGERS Trial: The Importance of Pre‐Intervention Social Involvement [PDF]

Alzheimers Dement
Abstract Background LatAm‐FINGERS is a non‐pharmacological multicenter randomized clinical trial aimed at preventing cognitive impairment. The intervention advocates for a lifestyle change based on diet, exercise, risk factor control, cognitive training, and socialization.
Cristalli C, Crivelli L, Caramelli P, Lopera F, Nitrini R, Sosa A, Salinas‐Contreras R, Suemoto C, Yassuda M, Sevlever G, Snyder H, Kivipelto M, Carrillo M, Acosta D, Charamelo A, Cusicanqui M, Custodio N, Delgado C, Duque L, Velazquez I, Leon‐Salas J, Allegri R, Calandri I.   +22 more
europepmc   +2 more sources

Frequency, entity and determinants of fatigue in Charcot–Marie–Tooth disease

European Journal of Neurology, Volume 30, Issue 3, Page 710-718, March 2023., 2023
Abstract Background and purpose Fatigue, a disabling symptom in many neuromuscular disorders, has been reported also in Charcot–Marie–Tooth disease (CMT). The presence of fatigue and its correlations in CMT was investigated. Methods The Modified Fatigue Impact Scale (MFIS) was administered to CMT patients from the Italian Registry and a control group ...
Marta Bellofatto, Alessandro Bertini, Irene Tramacere, Fiore Manganelli, Gian Maria Fabrizi, Angelo Schenone, Lucio Santoro, Tiziana Cavallaro, Marina Grandis, Stefano C. Previtali, Yuri Falzone, Isabella Allegri, Luca Padua, Costanza Pazzaglia, Daniela Calabrese, Paola Saveri, Aldo Quattrone, Paola Valentino, Stefano Tozza, Luca Gentile, Massimo Russo, Anna Mazzeo, Giuseppe Vita, Sylvie Piacentini, Chiara Pisciotta, Davide Pareyson, for the Italian CMT Network   +26 more
wiley   +1 more source

Inclusive Clinical Trials in Alzheimer’s Disease: A Latin American Perspective from LatAm FINGERS [PDF]

Alzheimers Dement
Abstract Background The LatAm‐FINGERS trial marks a pioneering initiative as the first non‐pharmacological clinical trial encompassing participants from 12 Latin American countries, including Argentina, Brazil, Bolivia, Chile, Colombia, Costa Rica, Ecuador, Dominican Republic, Mexico, Peru, Puerto Rico, and Uruguay.
Crivelli L, Calandri I, Caramelli P, Lopera F, Nitrini R, Sosa A, Salinas‐Contreras R, Suemoto C, Velilla L, Yassuda M, Sevlever G, Acosta D, Charamelo A, Cusicanqui M, Custodio N, Delgado C, Duque L, Velazquez I, Leon‐Salas J, Snyder H, Kivipelto M, Carrillo M, Allegri R, Consortium L.   +23 more
europepmc   +2 more sources

LatAm‐FINGERS: Navigating Diversity in the Engagement of a Subcontinental Trial for Dementia Prevention [PDF]

Alzheimers Dement
Abstract Background LatAm‐FINGERS is the first non‐pharmacological multicenter randomized clinical trial aimed at preventing cognitive impairment in Latin America. It encompasses twelve countries that collectively represent 45% of the territory in the Americas.
Calandri I, Crivelli L, Caramelli P, Lopera F, Nitrini R, Sosa A, Vellila L, Salinas‐Contreras R, Suemoto C, Yassuda M, Sevlever G, Acosta D, Charamelo A, Cusicanqui M, Custodio N, Delgado C, Duque L, Velazquez I, Leon‐Salas J, Snyder H, Carrillo M, Kivipelto M, Allegri R.   +22 more
europepmc   +2 more sources

El uso del estudio de casos en la investigación en psicoterapia

Psicodebate, 2015
Este trabajo revisa el estado actual de la investigación mediante Estudio de Casos (EC) en psicoterapia. El uso de esta metodología se remonta a los comienzos de la disciplina y es hoy una forma de investigación utilizada ampliamente.
Mariano G. Scandar
doaj   +1 more source