Results 11 to 20 of about 14,706 (161)
Kynurenine pathway metabolite alterations in Down syndrome and Alzheimer's disease. [PDF]
Alzheimers DementAbstract INTRODUCTION Down syndrome (DS) is a genetic disorder that leads to intellectual disability and accelerated aging, increasing the risk of Alzheimer's disease (AD). The pathophysiology of AD and DS is multifactorial, involving amyloid precursor protein overexpression, neuroinflammation, and oxidative stress.
Dos Reis RG +4 more
europepmc +2 more sources
Implementation of the Montessori model as a non‐pharmacological intervention for dementia in Latin America [PDF]
Alzheimers DementAbstract Almost 9.9 million people develop dementia each year, the majority (63%) of whom reside in low‐ and middle–income countries. In Latin America, this represents a major burden for health systems and society, that directly impacts quality of life of those living with dementia, family members and caregivers. Therefore, in the absence of accessible
Leon‐Salas J.
europepmc +2 more sources
Dementia diagnosis inequality between high‐income countries and Brazil: how challenging the diagnosis can be [PDF]
Alzheimers DementAbstract Background Early diagnosis is essential for effective dementia management, but LMICs, including Brazil, face a significant disparity in terms of resources for diagnosis compared to high‐income countries. Therefore, we aim to assess diagnostic methods and clinical practice tools available in specialized dementia care centers across Brazil ...
Silva I +14 more
europepmc +2 more sources
Nursing Open, Volume 10, Issue 8, Page 5749-5757, August 2023., 2023 Abstract Aims To evaluate the effectiveness of the ‘reserved therapeutic space’ intervention for improving the nurse–patient therapeutic relationship in acute mental health units in Spain. Design Multicentre intervention study with control group. Methods The study will be carried out in 12 mental health units.
Antonio R. Moreno‐Poyato +5 more
wiley +1 more source
Journal of Clinical Nursing, Volume 32, Issue 15-16, Page 5135-5146, August 2023., 2023 Abstract Aims and Objectives To explore the process of change within the clinical practice of nurses in mental health inpatient units in the context of a participatory process to improve the nurse–patient therapeutic relationship. Design Participatory Action Research. Methods Ninety‐six nurses from 18 mental health units participated.
Diana Tolosa‐Merlos +6 more
wiley +1 more source
A systematic review on the use of action research methods in mental health nursing care
Journal of Advanced Nursing, Volume 79, Issue 1, Page 372-384, January 2023., 2023 Abstract Aims To identify and synthesize evidence on the use of action research methods in mental health nursing care. Design Systematic review. Data Sources CINAHL, Web of Science, PubMed and Scopus databases were searched in January 2021. Review Methods Data were selected using the updated Preferred Reporting Items for Systematic Reviews and Meta ...
Antonio R. Moreno‐Poyato +12 more
wiley +1 more source
Journal of Clinical Nursing, Volume 32, Issue 1-2, Page 253-263, January 2023., 2023 Abstract Aims and objectives To explore the therapeutic relationship through the reflective practice of nurses in acute mental health units. Background In mental health units, the therapeutic relationship is especially relevant for increasing the effectiveness of nursing interventions. Reflective practice is considered an essential aspect for improving
Diana Tolosa‐Merlos +6 more
wiley +1 more source
Atypical astroglial pTDP‐43 pathology in astroglial predominant tauopathy
Neuropathology and Applied Neurobiology, Volume 47, Issue 7, Page 1109-1113, December 2021., 2021 We observed atypical astrocytic pTDP‐43 pathology in astroglial predominant tauopathy.
Ellen Gelpi +17 more
wiley +1 more source
JIMD Reports, Volume 62, Issue 1, Page 49-55, November 2021., 2021 Abstract Adenosine kinase (ADK) deficiency is a very rare inborn error of methionine and adenosine metabolism. It is characterized by developmental delay, hypotonia, epilepsy, facial dysmorphism, failure to thrive, transient liver dysfunction with cholestasis, recurrent hypoglycemia, and cardiac defects.
José A. Paz +9 more
wiley +1 more source
JCPP Advances, Volume 1, Issue 3, October 2021., 2021 There are currently no clinically useful, reliable and reproducible MRI classifiers for ASD. Prior studies with small sample sizes often reported inflated estimates from overfitted models. Our ensemble classifier using the largest structural MRI dataset from the ENIGMA consortium showed good fit and achieved a modest but significant classification AUC ...
Yanli Zhang‐James +4 more
wiley +1 more source