Results 1 to 10 of about 163,271 (261)
Current Biology, 2018 The German psychiatrist and neuropathologist Alois Alzheimer was fascinated by the symptoms of Auguste D., a 50-year-old woman admitted to the Frankfurt Psychiatric Hospital in 1901 who suffered from memory disturbances, paranoia and progressive confusion. After her death and autopsy, Alzheimer described histological alterations in her brain that later
Grøntvedt, G. +5 more
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Ameliorative effect of carveol on scopolamine induced memory impairment in rats [PDF]
Iranian Journal of Basic Medical Sciences, 2022 Objective(s): Carveol is a naturally occurring terpenoid with antispasmodic, carminative, astringent, indigestion, and dyspepsia properties, as well as anti-diabetic, anti-oxidant, anti-hyperlipidemia, and anti-inflammatory properties in the liver ...
Komal Latif +2 more
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Scientific Reports, 2023 Although beta-amyloid (Aβ) and phosphorylated tau remain the preferred targets for disease-modifying treatments (DMT) against Alzheimer’s disease (AD), part of the pathophysiological mechanisms of cognitive impairment are related to neuroinflammation and
Xavier Morató +46 more
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Nature Reviews Disease Primers, 2021 Alzheimer disease (AD) is biologically defined by the presence of β-amyloid-containing plaques and tau-containing neurofibrillary tangles. AD is a genetic and sporadic neurodegenerative disease that causes an amnestic cognitive impairment in its prototypical presentation and non-amnestic cognitive impairment in its less common variants.
David S. Knopman +7 more
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Alzheimer’s Research & Therapy, 2022 Background FACEmemory® is the first computerized, self-administered verbal episodic memory test with voice recognition. It can be conducted under minimal supervision and contains an automatic scoring system to avoid administrator errors.
Montserrat Alegret +24 more
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Scientific Reports, 2022 Optical coherence tomography angiography (OCT-A) allows the detection of retinal vessel density (VD) loss, which is a reflection of brain vascular pathology. We aimed to investigate differences in macular VD in the superficial plexus in a large cohort of
Marta Marquié +25 more
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Effect of Beta asarone on concentration of TNF-α in a rat model of Alzheimer’s disease [PDF]
Āsīb/shināsī-i Darmāngāhī-i Dāmpizishkī, 2021 Beta asarone which is the major component of Acorus tatarinowii Schott, can pass through the blood-brain-barrier and affect the central nervous system.
Golshid Saki +4 more
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The effect of aerobic training with saffron extract on plasma levels of apo E4 and presenilin gene in Alzheimer's rats by trimethyltin chloride [PDF]
Journal of Exercise & Organ Cross Talk, 2022 There is no treatment for Alzheimer's disease. However, some treatments can have a slowing and controlling effect on the disease process. The aim of this study was to investigate the effect of aerobic training with saffron extract on plasma levels of apo
Saeedeh Shadmehri, Afrooz Ramezanian
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Network: Computation in Neural Systems, 2011 Over the last three decades, advances in biochemical pathology and human genetics have illuminated one of the most enigmatic subjects in biomedicine--neurodegeneration. Eponymic diseases of the nervous system such as Alzheimer's, Parkinson's, and Huntington's diseases that were long characterized by mechanistic ignorance have yielded striking progress ...
Adam, Gazzaley, Scott A, Small
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Neurology, 2021 > With each passing day, I lose a yesterday, > > And as yesterdays amass into yesteryears, > > Stacks of color photographs fade to gray.
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