Results 1 to 10 of about 461,295 (348)

Ameliorative effect of carveol on scopolamine induced memory impairment in rats [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2022
Objective(s): Carveol is a naturally occurring terpenoid with antispasmodic, carminative, astringent, indigestion, and dyspepsia properties, as well as anti-diabetic, anti-oxidant, anti-hyperlipidemia, and anti-inflammatory properties in the liver ...
Komal Latif   +2 more
doaj   +1 more source

A randomized, open-label clinical trial in mild cognitive impairment with EGb 761 examining blood markers of inflammation and oxidative stress

open access: yesScientific Reports, 2023
Although beta-amyloid (Aβ) and phosphorylated tau remain the preferred targets for disease-modifying treatments (DMT) against Alzheimer’s disease (AD), part of the pathophysiological mechanisms of cognitive impairment are related to neuroinflammation and
Xavier Morató   +46 more
doaj   +1 more source

Automatized FACEmemory® scoring is related to Alzheimer’s disease phenotype and biomarkers in early-onset mild cognitive impairment: the BIOFACE cohort

open access: yesAlzheimer’s Research & Therapy, 2022
Background FACEmemory® is the first computerized, self-administered verbal episodic memory test with voice recognition. It can be conducted under minimal supervision and contains an automatic scoring system to avoid administrator errors.
Montserrat Alegret   +24 more
doaj   +1 more source

Differences in macular vessel density in the superficial plexus across cognitive impairment: the NORFACE cohort

open access: yesScientific Reports, 2022
Optical coherence tomography angiography (OCT-A) allows the detection of retinal vessel density (VD) loss, which is a reflection of brain vascular pathology. We aimed to investigate differences in macular VD in the superficial plexus in a large cohort of
Marta Marquié   +25 more
doaj   +1 more source

Alzheimer’s disease [PDF]

open access: yesNetwork: Computation in Neural Systems, 2011
Over the last three decades, advances in biochemical pathology and human genetics have illuminated one of the most enigmatic subjects in biomedicine--neurodegeneration. Eponymic diseases of the nervous system such as Alzheimer's, Parkinson's, and Huntington's diseases that were long characterized by mechanistic ignorance have yielded striking progress ...
Adam, Gazzaley, Scott A, Small
openaire   +4 more sources

Effect of Beta asarone on concentration of TNF-α in a rat model of Alzheimer’s disease [PDF]

open access: yesĀsīb/shināsī-i Darmāngāhī-i Dāmpizishkī, 2021
Beta asarone which is the major component of Acorus tatarinowii Schott, can pass through the blood-brain-barrier and affect the central nervous system.
Golshid Saki   +4 more
doaj   +1 more source

The effect of aerobic training with saffron extract on plasma levels of apo E4 and presenilin gene in Alzheimer's rats by trimethyltin chloride [PDF]

open access: yesJournal of Exercise & Organ Cross Talk, 2022
There is no treatment for Alzheimer's disease. However, some treatments can have a slowing and controlling effect on the disease process. The aim of this study was to investigate the effect of aerobic training with saffron extract on plasma levels of apo
Saeedeh Shadmehri, Afrooz Ramezanian
doaj   +1 more source

Effects of cromakalim (BRL 34915) on potassium conductances in CA3 neurons of the guinea-pig hippocampus in vitro [PDF]

open access: yes, 1989
The action of the potassium channel activator, cromakalim (BRL 34915), on membrane potential, input resistance and current-voltage-relationship of CA3 neurons in a slice preparation of the guinea-pig hippocampus was investigated by means of intracellular
Alzheimer, Christian   +2 more
core   +1 more source

Alzheimer's Villanelle [PDF]

open access: yesNeurology, 2021
> With each passing day, I lose a yesterday, > > And as yesterdays amass into yesteryears, > > Stacks of color photographs fade to gray.
openaire   +2 more sources

TDP-43 pathology in anterior temporal pole cortex in aging and Alzheimer’s disease

open access: yesActa Neuropathologica Communications, 2018
TDP-43 pathology was investigated in the anterior temporal pole cortex (ATPC) and orbital frontal cortex (OFC), regions often degenerated in frontotemporal lobar degenerations (FTLD), in aging and Alzheimer’s disease (AD).
Sukriti Nag   +5 more
doaj   +1 more source

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