Results 21 to 30 of about 461,295 (348)

Microglia TREM2R47H Alzheimer-linked variant enhances excitatory transmission and reduces LTP via increased TNF-α levels

open access: yeseLife, 2020
To study the mechanisms by which the p.R47H variant of the microglia gene and Alzheimer’s disease (AD) risk factor TREM2 increases dementia risk, we created Trem2R47H KI rats.
Siqiang Ren   +5 more
doaj   +1 more source

NECESIDADES DEL CUIDADOR DEL ENFERMO DE ALZHEIMER TERMINAL.

open access: yesEnfermería Global, 2005
La enfermedad de Alzheimer es la primera causa de demencia en la población occidental. Su carácter invalidante delega asistencia permanente desde los estadios moderados de la enfermedad por lo que la dependencia de cuidados constituye su principal ...
S. Sánchez Cánovas, R. Mears Baño
doaj   +1 more source

The value of hippocampal and temporal horn volumes and rates of change in predicting future conversion to AD. [PDF]

open access: yes, 2012
Hippocampal pathology occurs early in Alzheimer disease (AD), and atrophy, measured by volumes and volume changes, may predict which subjects will develop AD.
ADNI investigators   +5 more
core   +1 more source

Diyetle K Vitamini Alımı Bilişsel Performansı Etkiler mi?

open access: yesSakarya Tıp Dergisi, 2020
K vitamini yağda çözünen bir vitamin olup doğada filokinon (K1) ve menakinon (K2) formlarında bulunmaktadır. Menadion (K3) formu ise sentetik analog olarak kullanılmaktadır.
Aysegul Ugural, Aylin Ayaz
doaj   +1 more source

The role and therapeutic targeting of α-, β- and γ-secretase in Alzheimer's disease [PDF]

open access: yes, 2015
Alzheimer's disease (AD) is the most common form of dementia in the elderly and its prevalence is set to increase rapidly in coming decades. However, there are as yet no available drugs that can halt or even stabilize disease progression. One of the main
Baillie, George S.   +3 more
core   +1 more source

Attenuation of choroidal tickness in patients with Alzheimer disease: evidence from an Italian prospective study [PDF]

open access: yes, 2017
INTRODUCTION: To compare the 12-month choroidal thickness (CT) change between Alzheimer disease (AD) patients and normal subjects. METHODS: In this prospective, observational study, 39 patients with a diagnosis of mild to moderate AD and 39 age ...
Campanelli, A   +7 more
core   +1 more source

Una escala para medir la aflicción del cuidador del paciente con Alzheimer

open access: yesVoces desde el Trabajo Social, 2018
El objetivo de este estudio fue introducir el concepto de aflicción del cuidador o cuidadora del paciente con la enfermedad de Alzheimer y validar al español una escala breve para medir sus niveles y así evaluar la efectividad de la intervención ...
Jaime Alvelo Burgos   +1 more
doaj   +1 more source

The Role of Ca2+ Signaling in Aging and Neurodegeneration: Insights from Caenorhabditis elegans Models

open access: yesCells, 2020
Ca2+ is a ubiquitous second messenger that plays an essential role in physiological processes such as muscle contraction, neuronal secretion, and cell proliferation or differentiation.
Javier Alvarez   +4 more
doaj   +1 more source

Using the A/T/N framework to examine driving in preclinical Alzheimer’s disease [PDF]

open access: yes, 2018
The A/T/N classification system is the foundation of the 2018 NIA-AA Research Framework and is intended to guide the Alzheimer disease (AD) research agenda for the next 5–10 years.
Ances, Beau M   +9 more
core   +3 more sources

Auditory Agnosia and Alzheimer's Disease: a Cohort Study

open access: yesRevista Finlay, 2023
Foundation: recent evidence suggests that disorders caused by the onset of Alzheimer's disease can cause sound agnosia. Objective: to investigate whether patients with mild cognitive impairment and dementia as a symptom of Alzheimer's recognize ...
Manuel Conrado Ezcurdia Bárzaga   +2 more
doaj  

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