Results 21 to 30 of about 701,822 (352)

Mapas de color: Un proyecto de intervención artística con personas con alzheimer y otras demencias.

Encuentros, 2022
Mapas de color, un mundo de memorias, es un proyecto de Arte y Salud (AR.S) financiado por la beca PIRTU de la Junta de Castilla y León y Fondo Social Europeo (ORDEN EDU/1204/2010, de 26 de Agosto), implementado en el Centro de Referencia Estatal de ...
Lorena López-Méndez
doaj   +1 more source

Two Randomized Phase 3 Studies of Aducanumab in Early Alzheimer’s Disease

The journal of prevention of Alzheimer's disease, 2022
Alzheimer’s disease is a progressive, irreversible, and fatal disease for which accumulation of amyloid beta is thought to play a key role in pathogenesis.
S. Budd Haeberlein, P. Aisen, F. Barkhof, S. Chalkias, T. Chen, S. Cohen, G. Dent, O. Hansson, K. Harrison, C. V. von Hehn, T. Iwatsubo, C. Mallinckrodt, C. Mummery, K. K. Muralidharan, I. Nestorov, L. Nisenbaum, R. Rajagovindan, L. Skordos, Y. Tian, C. V. van Dyck, B. Vellas, S. Wu, Y. Zhu, A. Sandrock   +23 more
semanticscholar   +1 more source

Report summary - Prevalence and monetary costs of dementia in Canada (2016): a report by the Alzheimer Society of Canada

Health Promotion and Chronic Disease Prevention in Canada, 2016
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Alzheimer Society of Canada
doaj   +1 more source

Intervención psicológica familiar en la enfermedad de alzheimer

INFAD, 2020
La demencia es un síndrome adquirido, de naturaleza orgánica caracterizado por un deterioro permanente de la memoria y de otras funciones intelectuales, y frecuentemente acompañado de otros trastornos psiquiátricos, que ocurren sin alteración del nivel ...
Francisco Javier Balea Fernández, Javier Alonso Ramírez   +1 more
doaj   +1 more source

Neuroinflammation in Alzheimer's Disease

Lancet Neurology, 2015
Increasing evidence suggests that Alzheimer's disease pathogenesis is not restricted to the neuronal compartment but strongly interacts with immunological mechanisms in the brain. Misfolded and aggregated proteins bind to pattern recognition receptors on
M. Heneka, M. Carson, J. E. El Khoury, G. Landreth, Frederik Brosseron, D. Feinstein, A. Jacobs, T. Wyss-Coray, J. Vitorica, R. Ransohoff, K. Herrup, S. Frautschy, B. Finsen, G. Brown, Alexei Verkhratsky, K. Yamanaka, J. Koistinaho, E. Latz, A. Halle, G. Petzold, T. Town, D. Morgan, Mari L. Shinohara, V. Perry, C. Holmes, N. Bazan, D. Brooks, S. Hunot, B. Joseph, N. Deigendesch, O. Garaschuk, E. Boddeke, C. Dinarello, J. Breitner, G. Cole, D. Golenbock, Markus P. Kummer   +36 more
semanticscholar   +1 more source

Biomarkers in alzheimer’s dementia: health system and ageism

INFAD, 2020
The aging of the population in Spain is an issue that not only concerns the health of the population and Health, but also has important repercussions on the economy, family structure, sustainability of the pension system, etc.
Francisco Javier Balea Fernández, Javier Alonso Ramírez   +1 more
doaj   +1 more source

The diagnosis of mild cognitive impairment due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer’s disease

Alzheimer's & Dementia, 2011
The National Institute on Aging and the Alzheimer's Association charged a workgroup with the task of developing criteria for the symptomatic predementia phase of Alzheimer's disease (AD), referred to in this article as mild cognitive impairment due to AD.
M. Albert, S. DeKosky, D. Dickson, B. Dubois, H. Feldman, Nick C Fox, A. Gamst, D. Holtzman, W. Jagust, R. Petersen, P. Snyder, M. Carrillo, B. Thies, C. Phelps   +13 more
semanticscholar   +1 more source

Pathways to participation – a scoping review outlining barriers and enablers to participation in dementia research

The Journal of Prevention of Alzheimer's Disease
Background: Ongoing participant recruitment challenges in dementia research highlight the need to understand public perspectives on research participation.
Lukas A. Duffner, Soraya Moradi-Bachiller, Dianne Gove, Ana M. Diaz-Ponce, Angela Bradshaw, Jean Georges   +5 more
doaj   +1 more source

Microglia TREM2R47H Alzheimer-linked variant enhances excitatory transmission and reduces LTP via increased TNF-α levels

eLife, 2020
To study the mechanisms by which the p.R47H variant of the microglia gene and Alzheimer’s disease (AD) risk factor TREM2 increases dementia risk, we created Trem2R47H KI rats.
Siqiang Ren, Wen Yao, Marc D Tambini, Tao Yin, Kelly A Norris, Luciano D'Adamio   +5 more
doaj   +1 more source

Alzheimer Disease: An Update on Pathobiology and Treatment Strategies

Cell, 2019
Alzheimer disease (AD) is a heterogeneous disease with a complex pathobiology. The presence of extracellular β-amyloid deposition as neuritic plaques and intracellular accumulation of hyperphosphorylated tau as neurofibrillary tangles remains the primary
Justin M. Long, D. Holtzman
semanticscholar   +1 more source