Results 41 to 50 of about 233,218 (311)

New Alzheimer's Association report reveals 1 in 3 seniors dies with Alzheimer's or another dementia

, 2013
2.3 Million Americans are “Long-Distance Caregivers” for people with Alzheimer’s; Costs for Long-Distance Caregivers are Almost Twice as High.According to the Alzheimer\u27s Association 2013 Alzheimer\u27s Disease Facts and Figures ...
Alzheimer's Association
core   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Carolyn Halpin-Healy on her experience as Co-Founder and Executive Director of Arts & Minds in conversation with Sara Torres

Arte, Individuo y Sociedad, 2017
Arts&Minds is a non-for-prfit organization and its goal is to improve well-being for people living with dementia and their cargivers through meaningful contact with art.
Sara Torres, Carolyn Halpin-Healy
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Unveiling the sound of the cognitive status: Machine Learning-based speech analysis in the Alzheimer’s disease spectrum

Alzheimer’s Research & Therapy
Background Advancement in screening tools accessible to the general population for the early detection of Alzheimer’s disease (AD) and prediction of its progression is essential for achieving timely therapeutic interventions and conducting decentralized ...
Fernando García-Gutiérrez, Montserrat Alegret, Marta Marquié, Nathalia Muñoz, Gemma Ortega, Amanda Cano, Itziar De Rojas, Pablo García-González, Clàudia Olivé, Raquel Puerta, Ainhoa García-Sanchez, María Capdevila-Bayo, Laura Montrreal, Vanesa Pytel, Maitee Rosende-Roca, Carla Zaldua, Peru Gabirondo, Lluís Tárraga, Agustín Ruiz, Mercè Boada, Sergi Valero   +20 more
doaj   +1 more source

Investigation of the anti-amyloidogenic and antioxidant effects of silver nanoparticles synthesised with leaf extract of Thymus kotschyanus Boiss [PDF]

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, 2023
Introduction: The extract of Thymus kotschyanus Boiss, in addition to its antioxidant properties, also has a marvellous anti-amyloidogenic effectthat can be used for the treatment of amyloidosis.
Zolfaghar Lotfi, Fatemeh Maleki, Somayeh Farahmand   +2 more
doaj  

Effectiveness of a Family Support Intervention on Caregiving Burden in Family of Elderly Patients With Cognitive Decline After the COVID-19 Lockdown

Frontiers in Psychiatry, 2021
Background: The coronavirus disease 2019 (COVID-19) pandemic had a great impact on patients with cognitive decline or dementia. The lockdown period may exacerbate behavioral disorders and worsen distress of caregivers.
Luca Cravello, Eleonora Martini, Niccolò Viti, Cristina Campanello, Francesca Assogna, Daniele Perotta   +5 more
doaj   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

World Alzheimer Report 2010

, 2010
The World Alzheimer Report 2010 provides the clearest, most comprehensive global picture yet of the economic impact of Alzheimer\u27s disease and dementia. The report includes an estimate of the worldwide cost of dementia, including direct medical costs,
Alzheimer's Disease International
core   +1 more source

Changes in choroidal thickness quantified by Optical Coherence Tomography across cognitive impairment: data from the NORFACE cohort

Alzheimer’s Research & Therapy
Background Optical coherence tomography (OCT) enables high-resolution imaging of ocular structures in health and disease. Choroid thickness (CT) is a key vascular retinal parameter that can be assessed by OCT and might be relevant in the evaluation of ...
Luis Castilla-Martí, Ainhoa García-Sánchez, Joan Martínez, Maitée Rosende-Roca, Liliana Vargas, Juan Pablo Tartari, Federico Casales, José Nelet Rodríguez, Natali Bein, Montserrat Alegret, Gemma Ortega, Ana Espinosa, Ángela Sanabria, Alba Pérez-Cordón, Nathalia Muñoz, Fernando García-Gutiérrez, Josep Blazquez-Folch, Andrea Miguel, Itziar de Rojas, Pablo García-González, Raquel Puerta, Clàudia Olivé, Maria Capdevila, Álvaro Muñoz-Morales, Paula Bayón-Buján, Amanda Cano, Victoria Fernández, Sergi Valero, Lluís Tárraga, Agustín Ruiz, Mercè Boada, Miguel Castilla-Martí, Marta Marquié   +32 more
doaj   +1 more source