Results 41 to 50 of about 701,822 (352)

Exectuive summary: an economic analysis of home care services for people with dementia [PDF]

, 2015
This summary presents Trépel’s expert analysis of home care for people with dementia in the context of currently identified needs in Ireland, focusing on who provides home care, what care is provided and when.
Begley, Emer, Trépel, Dominic, Crean, Mags   +2 more
core   +1 more source

2009 Alzheimer's Disease

, 2009
Alzheimer’s disease triples healthcare costs for Americans aged 65 or older 2009 Alzheimer’s Disease Facts and Figures provides a statistical resource for U.S.
Alzheimer's Association
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Exploring sex differences in Alzheimer’s disease: a comprehensive analysis of a large patient cohort from a memory unit

Alzheimer’s Research & Therapy
Background Alzheimer’s disease (AD) stands as the leading cause of dementia worldwide, and projections estimate over 150 million patients by 2050. AD prevalence is notably higher in women, nearly twice that of men, with discernible sex differences in ...
Maitee Rosende-Roca, Fernando García-Gutiérrez, Yahveth Cantero-Fortiz, Montserrat Alegret, Vanesa Pytel, Pilar Cañabate, Antonio González-Pérez, Itziar de Rojas, Liliana Vargas, Juan Pablo Tartari, Ana Espinosa, Gemma Ortega, Alba Pérez-Cordón, Mariola Moreno, Sílvia Preckler, Susanna Seguer, Miren Jone Gurruchaga, Lluís Tárraga, Agustín Ruiz, Sergi Valero, Mercè Boada, Marta Marquié   +21 more
doaj   +1 more source

2025 Alzheimer's disease facts and figures

Alzheimer's & Dementia
This article describes the public health impact of Alzheimer's disease (AD), including prevalence and incidence, mortality and morbidity, use and costs of care, and the ramifications of AD for family caregivers, the dementia workforce, and society.

semanticscholar   +1 more source

Perusinis II. Fall: Der Alzheimer Patient R.M. Geschichte, Genealogie und Genetik eines psychiatriehistorischen Falls [PDF]

, 2012
1.American Journal of Alzheimer`s Disease and Other Dementias: 2010; 25:189-192 100th anniversary of PERUSINI`S SECOND CASE: PATIENT RM and his KINDRED
Braun, Birgit
core  

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Interest in genetic susceptibility testing and disclosure of AD dementia risk in cognitively normal adults: a survey study

Alzheimer’s Research & Therapy
Background Apolipoprotein-E (APOE) genetic testing for Alzheimer’s disease is becoming more important as clinical trials are increasingly targeting individuals carrying APOE-ε4 alleles. Little is known about the interest in finding out one’s genetic risk
Lisa Waterink, Larissa A. Masselink, Sven J. van der Lee, Leonie N. C. Visser, Solange Cleutjens, Jetske van der Schaar, Argonde C. van Harten, Philip Scheltens, Sietske A. M. Sikkes, Wiesje M. van der Flier, Marissa D. Zwan   +10 more
doaj   +1 more source

Targeting brain, body and heart for cognitive health and dementia prevention [PDF]

, 2012
This report looks into the current research regarding dementia and Alzheimer\u27s disease prevention and offers ideas for possible future solutions. Prevention of dementia is the ultimate aim of a large, albeit under resourced, international ...
Elodie O'Connor, Maree Farrow
core  

Alzheimer's Disease Facts and Figures

, 2010
Includes a Special Report on Race, Ethnicity and Alzheimer’s Disease2010 Alzheimer’s Disease Facts and Figures provides a statistical resource for United States data related to Alzheimer’s disease, the most common type of dementia ...
Alzheimer's Association
core   +1 more source