Results 41 to 50 of about 163,271 (261)

MODELING FACTORS CAUSING ALZHEIMER’S DISEASE USING LOGIT, PROBIT, AND GOMPIT LINK FUNCTIONS IN GENERALIZED LINEAR MODEL

Barekeng
This study addresses the ongoing challenge of clarifying the risk factors contributing to Alzheimer's disease, a neurodegenerative condition marked by progressive cognitive decline and memory dysfunction, with cases rising globally.
Ardi Kurniawan, Gabriella Agnes Budijono, Kimberly Maserati Siagian, Adrian Wahyu Abdillah   +3 more
doaj   +1 more source

Uncovering potential neuroprotective flavonoids for Alzheimer's disease using cutting-edge molecular simulation and in vitro SHSY-5Y analysis [PDF]

Journal of Pharmacy & Pharmacognosy Research
Context: Alzheimer's disease (AD) is a debilitating neurodegenerative condition primarily afflicting the elderly, causing a progressive decline in cognitive function.
Fadilah Fadilah, Immanuelle Kezia, Linda Erlina   +2 more
doaj   +1 more source

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

Macular vessel density in the superficial plexus is not a proxy of cerebrovascular damage in non-demented individuals: data from the NORFACE cohort

Alzheimer’s Research & Therapy
Introduction Optical coherence tomography angiography (OCT-A) is a novel tool that allows the detection of retinal vascular changes. We investigated the association of macular vessel density (VD) in the superficial plexus assessed by OCT-A with measures ...
Ainhoa García-Sánchez, Oscar Sotolongo-Grau, Juan Pablo Tartari, Ángela Sanabria, Ester Esteban - De Antonio, Alba Pérez-Cordón, Montserrat Alegret, Vanesa Pytel, Joan Martínez, Núria Aguilera, Itziar de Rojas, Amanda Cano, Pablo García-González, Raquel Puerta, Clàudia Olivé, Maria Capdevila, Fernando García-Gutiérrez, Assumpta Vivas, Marta Gómez-Chiari, Juan Giménez, Miguel Ángel Tejero, Miguel Castilla-Martí, Luis Castilla-Martí, Lluís Tárraga, Sergi Valero, Agustín Ruiz, Mercè Boada, Marta Marquié, on behalf of the FACEHBI study group , on behalf of the BIOFACE study group   +29 more
doaj   +1 more source

¿Vivir en/entre sonrisas? Envejecimiento y Alzheimer. / To live in/among smiles? Aging and Alzheimer.

Novedades en Población, 2021
This research characterizes the demographic aging in the Artemisa province in the year 2018. The analysis is built from the calculation of demographic indicators that allow the stablishment of an interrelation among ages.
Sahilí Cristiá Lara, Leonardo Cristiá Lara   +1 more
doaj  

Posterior Cortical Atrophy in the Asia‐Pacific: A Report From the PCA Asian Workgroup

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Posterior Cortical Atrophy (PCA) is a distinct dementia syndrome primarily affecting spatial abilities and visual processing. It is associated with degeneration in the posterior part of the brain. PCA is subclassified into PCA‐pure and PCA‐plus syndromes based on consensus criteria.
Yuttachai Likitjaroen, Ya‐Ting Chang, Levinia Lim, Pai‐Yi Chiu, Jung‐Lung Hsu, SangYun Kim, Wataru Narita, Na Young Ryoo, Kyoko Suzuki, Nagaendran Kandiah, Sebastian Crutch, Ming‐Chyi Pai   +11 more
wiley   +1 more source

ADVANCEMENTS IN ALZHEIMER’S DIAGNOSIS THROUGH MRI USING BAYESIAN CONVOLUTIONAL NEURAL NETWORKS AND VARIATIONAL INFERENCE

Barekeng
Alzheimer’s disease is one of the brain disorders that can be deadly in older. The disease is less treated and less recognized, but Alzheimer’s disease is now a significant public health problem.
Alifia Ardha Nareswari, Dina Tri Utari
doaj   +1 more source

Diyetle K Vitamini Alımı Bilişsel Performansı Etkiler mi?

Sakarya Tıp Dergisi, 2020
K vitamini yağda çözünen bir vitamin olup doğada filokinon (K1) ve menakinon (K2) formlarında bulunmaktadır. Menadion (K3) formu ise sentetik analog olarak kullanılmaktadır.
Aysegul Ugural, Aylin Ayaz
doaj   +1 more source

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source

Multicomponent reactions driving the discovery and optimization of agents targeting central nervous system pathologies

Beilstein Journal of Organic Chemistry
The ongoing quest to discover effective treatments for diseases remains a significant challenge for the scientific community. Multicomponent reactions (MCRs) have emerged as powerful tools in accelerating drug discovery, enabling the rapid generation of ...
Lucía Campos-Prieto, Aitor García-Rey, Eddy Sotelo, Ana Mallo-Abreu   +3 more
doaj   +1 more source