Results 111 to 120 of about 1,582,399 (399)
HPDL Variant Type Correlates With Clinical Disease Onset and Severity
ABSTRACT Objective Recently, a mitochondrial encephalopathy due to biallelic HPDL variants was described, associated with a broad range of clinical manifestations ranging from severe, infantile‐onset neurodegeneration to adolescence‐onset hereditary spastic paraplegia. HPDL converts 4‐hydroxyphenylpyruvate acid (4‐HPPA) into 4‐hydroxymandelate (4‐HMA),
Eun Hye Lee+19 more
wiley +1 more source
Neuroscience: who are we? [PDF]
Writing for the interested public, Gazzaniga marshals recent findings from neuroscience to demonstrate the crucial roles of social interactions and context in the evolution of human ...
Adolphs, Ralph
core
Theoretical Models of Neural Development
Constructing a functioning nervous system requires the precise orchestration of a vast array of mechanical, molecular, and neural-activity-dependent cues.
Geoffrey J. Goodhill
doaj
Neuroscience and the Adjudication of Uncontrollability
During the Italian Renaissance, Leonardo da Vinci conducted research on neuroscience, striving to explain “how the brain processes visual and other sensory input, and integrates that information via the soul”.
Mizuki Hashiguchi
doaj +1 more source
Can Religiosity Be Explained by ‘Brain Wiring’? An Analysis of US Adults’ Opinions
Studies examining how religion shapes individuals’ attitudes about science have focused heavily on a narrow range of topics, such as evolution. This study expands this literature by looking at how religion influences individuals’ attitudes ...
Sharan Kaur Mehta+2 more
doaj +1 more source
The Case of a 67‐Year‐Old Man With Memory Difficulties and Altered Sleep
Annals of Clinical and Translational Neurology, EarlyView.
Wesley Peng, Borna Bonakdarpour
wiley +1 more source
ABSTRACT Objective Increasing evidence shows that patients with intracerebral hemorrhage (ICH) can achieve better‐than‐expected outcomes with aggressive therapy. However, real‐world long‐term data, patient‐centered outcomes, and societal measures after maximal ICH treatment are lacking.
Anne Mrochen+11 more
wiley +1 more source
Learned helplessness at fifty: Insights from neuroscience.
Learned helplessness, the failure to escape shock induced by uncontrollable aversive events, was discovered half a century ago. Seligman and Maier (1967) theorized that animals learned that outcomes were independent of their responses-that nothing they ...
S. Maier, M. Seligman
semanticscholar +1 more source
Clinical Trial Readiness in Limb Girdle Muscular Dystrophy R1 (LGMDR1): A GRASP Consortium Study
ABSTRACT Objective Identifying functional measures that are both valid and reliable in the limb girdle muscular dystrophy (LGMD) population is critical for quantifying the level of functional impairment related to disease progression in order to establish clinical trial readiness in the context of anticipated therapeutic trials.
Stephanie M. Hunn+29 more
wiley +1 more source