Results 131 to 140 of about 1,627,357 (397)

Childhood Brain Development, the Educational Achievement Gap, and Cognitive Enhancement

open access: yesFrontiers in Pharmacology, 2018
Research on the effects of adversity on the brain of children initially encountered strong skepticism mainly due to the fear of stigmatization and the potential pathologizing of poverty as a disease. Despite initial resistance, an increasing body of work
Fabrice Jotterand, Fabrice Jotterand
doaj   +1 more source

A Novel C19orf47‐AKT2 Chimeric RNA Generated by Cis‐Splicing of Adjacent Genes Is Associated With Glioblastoma Prognosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Malignant gliomas pose significant therapeutic challenges. This study aimed to identify and characterize a novel chimeric RNA in glioma and assess its clinical and functional significance for precision treatment. Methods The C19orf47‐AKT2 chimeric RNAs were identified through RNA sequencing and validated by polymerase chain reaction.
Zihan Wang   +11 more
wiley   +1 more source

Adeno-Associated Virus Technologies and Methods for Targeted Neuronal Manipulation

open access: yesFrontiers in Neuroanatomy, 2019
Cell-type-specific expression of molecular tools and sensors is critical to construct circuit diagrams and to investigate the activity and function of neurons within the nervous system.
Leila Haery   +12 more
doaj   +1 more source

Session 5: Development, Neuroscience and Evolutionary Psychology [PDF]

open access: yes, 2002
Proceedings of the Pittsburgh Workshop in History and Philosophy of Biology, Center for Philosophy of Science, University of Pittsburgh, March 23-24 2001 Session 5: Development, Neuroscience and Evolutionary ...
Machamer, Peter   +3 more
core  

Advances in neuroscience [PDF]

open access: yesScience Advances, 2017
Kevin S. LaBar The burgeoning field of neuroscience is at an important nexus of discovery. The pace of innovation is accelerating along with increased curiosity about how the most mysterious organ of the body works. Emerging technologies, such as optogenetics, permit an inquiry into brain function at unprecedented levels of detail and sophistication.
openaire   +3 more sources

Neuroethics: the institutionalization of ethics in neuroscience

open access: yesRevista Bioética
Recent advances in neuroscience have led to numerous ethical questions. Neuroethics is the study of ethical, legal and social advancements in neuroscience which, despite being a recently developed discipline, has a long historical tradition.
Amer Cavalheiro Hamdan
doaj   +1 more source

In Vitro Modeling of Natural Killer Cell Cytotoxicity to Inform Personalized ALS Therapeutics

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Natural killer (NK) cells might contribute to motor neuron death in amyotrophic lateral sclerosis (ALS) through direct cytotoxicity, a process that could be inhibited with the FDA‐approved JAK/STAT pathway inhibitor, tofacitinib. This study aimed to verify that tofacitinib can suppress NK cell cytotoxicity, investigate if immune cell
Benjamin J. Murdock   +8 more
wiley   +1 more source

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