Results 61 to 70 of about 619,328 (341)
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Transfer entropy—a model-free measure of effective connectivity for the neurosciences
Journal of Computational Neuroscience, 2010 Understanding causal relationships, or effective connectivity, between parts of the brain is of utmost importance because a large part of the brain’s activity is thought to be internally generated and, hence, quantifying stimulus response relationships ...
Raul Vicente +3 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu +6 more
wiley +1 more source
História, Ciências, Saúde: Manguinhos, 2006 Este artigo analisa o sucesso das novas tecnologias de visualização médica, as quais têm dado relevância ao interior do corpo humano que não encontra precedentes nas nossas sociedades.
Francisco Ortega
doaj +1 more source
The role of empathy in shared intentionality: Contributions from Inter-Processual Self theory
Frontiers in Psychology, 2023 Research in psychology related to the conceptualization of empathy has been on the rise in the last decades. However, we argue that there is still space for further research to help capture the important notion of empathy and its theoretical and ...
Elkin O. Luis +7 more
doaj +1 more source
The impact of Hnrnpl deficiency on transcriptional patterns of developing muscle cells
FEBS Open Bio, EarlyView.We performed nanopore whole‐transcriptome sequencing comparing RNA from Hnrnpl‐knockdown versus control C2C12 myoblasts to investigate the contributions of Hnrnpl to muscle development. Our results indicate that Hnrnpl regulates the expression of genes involved with Notch signaling and skeletal muscle, particularly splicing patterns of specific muscle ...
Hannah R. Littel +8 more
wiley +1 more source
Philosophical and Methodological Problems of Modern Neurotheology
RUDN Journal of Philosophy, 2023 In modern science, research aimed at studying the functioning of the human brain under the influence of various factors of the social and natural environment, including religious practices, both personal and social, is relevant.
Aleksey A. Lagunov, Svetlana Yu. Ivanova
doaj +1 more source
Educación y Educadores, 2012 Ante a efetividade da neurociência no desenvolvimento de diferentes áreas do conhecimento, propõe-se adotar o ensino dessa disciplina nos programas de educação física, com o objetivo de que estudantes e profissionais aprendam estratégias didáticas que ...
André Luiz Monezi-Andrade +3 more
doaj
A scientific rationale for consciousness
Substantia, 2019 Consciousness is a concept that can be easily experimented but not easily defined. We show that the same observation applies to information, entropy and even energy.
Marc Henry, Jean-Pierre Gerbaulet
doaj +1 more source
Somatic comorbidity and the progression of cognitive impairment
Frontiers in Aging Neuroscience, 2023 BackgroundThere are usually multiple factors underlying dementia in old age. Somatic comorbidity is one important element that influences the progression of cognitive impairment.ObjectiveThe goal of this study was to assess the relationship between the ...
Leszek Bidzan +8 more
doaj +1 more source