Results 61 to 70 of about 804,053 (383)

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Making Room for Every Voice: Reimagining Person‐Centred Care in the Neurosciences

open access: yesHealth Expectations
Background This Special Issue of Health Expectations brings together 38 articles that exemplify the growing commitment to person‐centred care in the neurosciences. Moving beyond a historically brain‐centric model, these contributions reflect a more human
Miguel Toribio‐Mateas, Gareth Noble
doaj   +1 more source

Psicanálise e neurociências: um mapa dos debates Psicoanálisis y neurociencias: un mapa de los debates Psychoanalysis and neurosciences: a map of the debates

open access: yesPsicologia em Estudo, 2010
Este artigo pretende apresentar um mapa panorâmico dos debates em torno da relação e da possível articulação entre a psicanálise e as neurociências. No campo psicanalítico são identificados três grupos principais, definidos a partir de seus pressupostos:
Marcia Moraes Davidovich, Monah Winograd
doaj   +1 more source

Language acquisition and speech rhythm patterns: an auditory neuroscience perspective

open access: yesRoyal Society Open Science, 2022
All human infants acquire language, but their brains do not know which language/s to prepare for. This observation suggests that there are fundamental components of the speech signal that contribute to building a language system, and fundamental neural ...
Usha Goswami
doaj   +1 more source

Research on motor neuron diseases konzo and neurolathyrism : trends from 1990 to 2010 [PDF]

open access: yes, 2012
Konzo (caused by consumption of improperly processed cassava, Manihot esculenta) and neurolathyrism (caused by prolonged overconsumption of grass pea, Lathyrus sativus) are two distinct non-infectious upper motor neurone diseases with identical clinical ...
Diasolua Ngudi, Delphin   +3 more
core   +2 more sources

Resisting neurosciences and sustaining history

open access: yesHistory of the Human Sciences, 2019
The article began life as, and retains the character of, spoken argument for not allowing the neurosciences to shape the agenda of the history of the human sciences.
Roger Smith
semanticscholar   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Etiopathogenesis of Suicide: A Conceptual Analysis of Risk and Prevention Within a Comprehensive, Deterministic Model

open access: yesFrontiers in Psychology, 2019
Suicide is a rising global health concern receiving disproportionate attention in comparison to other health conditions. In spite of substantial technological and scientific advancements, suicide research has continued to move slowly in terms of clinical
Jack C. Lennon   +2 more
doaj   +1 more source

Consciousness And Self-Identity: A Phenomenological View on a Cognitive Issue [PDF]

open access: yes, 2011
The paper aims at analyzing the inner development of self-identity from its pre-reflective level to the full awareness one. The recent findings of neurosciences and cognitive studies suggest focusing attention on the complex relation between self as ...
Zippel, Nicola
core   +1 more source

Neurosciences in Brazil: a bibliometric study of main characteristics, collaboration and citations

open access: yesScientometrics, 2016
Brazilian scientific output in the field of Neurosciences is analyzed based on articles indexed in Web of Science from 2006 to 2013 according to bibliometric indicators of production, collaboration, impact and keywords analysis.
Natascha Helena Franz Hoppen   +1 more
semanticscholar   +1 more source

Home - About - Disclaimer - Privacy