Results 1 to 10 of about 22,415 (298)
The adult mouse hippocampal progenitor is neurogenic but not a stem cell [PDF]
, 2005 The aim of this investigation was to characterize the proliferative precursor cells in the adult mouse hippocampal region. Given that a very large number of new hippocampal cells are generated over the lifetime of an animal, it is predicted that a neural
Bartlett, P. F., Bull, N. D.
core +2 more sources
How Growth Cones Sense Extracellular Cues and Drive Neuronal Migration
BioEssays, EarlyView.Migrating neurons and growing axons utilize structurally and functionally similar growth cones to detect guidance cues. Shared receptors and signaling pathways mediate cytoskeletal reorganization to direct movement. This conserved mechanism underlies both neuronal migration and axon extension, providing insights into neuronal development and potential ...
Takahiro Kanzawa +3 more
wiley +1 more source
Antigenic and Genotypic Similarity between Primary Glioblastomas and Their Derived Neurospheres [PDF]
Journal of Oncology, 2011 Formation of neurospheres (NS) in cultures of glioblastomas (GBMs), with self-renewal, clonogenic capacities, and tumorigenicity following transplantation into immunodeficient mice, may denounce the existence of brain tumor stem cells (BTSCs) in vivo. In sixteen cell lines from resected primary glioblastomas, NS showed the same genetic alterations as ...
Valentina Caldera +6 more
openaire +3 more sources
Exploring Multi‐Organ Crosstalk via the TissUse HUMIMIC Chip System: Lessons Learnt So Far
Biotechnology and Bioengineering, EarlyView.ABSTRACT Three‐dimensional (3D) in vitro cell culture models have revolutionized biomedical research by mimicking the complex 3D in vivo environment in the human body. Different types of 3D models have been established, including heterotypic systems such as, organ‐on‐a‐chips which have been further developed into multiorgan‐on‐chip systems that ...
Filsan Ahmed Abokor +5 more
wiley +1 more source
BMC Neuroscience, 2005 Background The fetal cortical neuroepithelium is a mosaic of distinct progenitor populations that elaborate diverse cellular fates. Ethanol induces apoptosis and interferes with the survival of differentiating neurons.
Tingling Joseph D +5 more
doaj +1 more source
Somatic cell reprogramming for Parkinson's disease treatment
Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley +1 more source
Development of Circadian Oscillators in Neurosphere Cultures during Adult Neurogenesis
PLoS ONE, 2015 Circadian rhythms are common in many cell types but are reported to be lacking in embryonic stem cells. Recent studies have described possible interactions between the molecular mechanism of circadian clocks and the signaling pathways that regulate stem ...
Astha Malik +3 more
semanticscholar +1 more source
Adipose stem cell neurospheres for Huntington's disease
Cytotherapy, 2017 restriction
Seung Chan Kim, Wooseok Im
openaire +4 more sources
The doublecortin-expressing population in the developing and adult brain contains multipotential precursors in addition to neuronal-lineage cells [PDF]
, 2007 Doublecortin (DCX) has recently been promulgated as a selective marker of cells committed to the neuronal lineage in both the developing and the adult brain.
Adams, D. J. +3 more
core +1 more source
International Journal of Cancer, EarlyView.What's New? The anti‐aging protein klotho (KL) is a potential tumor suppressor and prognostic marker in glioblastoma. Little is known, however, about its mechanism of action and clinical relevance. This study examined KL expression in the setting of persistent inflammation and other stressors, including radiotherapy.
Andrea Galluzzo +19 more
wiley +1 more source